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plasmodium

Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates

December 12, 2018 - 16:13 -- Open Access
Author(s): 
Jyotsana Dixit, Arun Zachariah, Sajesh P. K., Bathrachalam Chandramohan, Vinoth Shanmuganatham, K. Praveen Karanth
Reference: 
PLoS Negl Trop Dis 12(12): e0006801

Many human parasites and pathogens have closely related counterparts among non-human primates.

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Neddylation contributes to CD4+ T cell-mediated protective immunity against blood-stage Plasmodium infection

November 28, 2018 - 15:26 -- Open Access
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Author(s): 
Qianqian Cheng, Jian Liu, Yujun Pei, Yaolin Zhang, Dawang Zhou, Weiqing Pan, Jiyan Zhang
Reference: 
PLoS Pathog 14(11): e1007440

Plasmodium infection, both for IFN-γ-dependent effector mechanisms and providing B cell helper signals.

An Anopheles aquasalis GATA factor Serpent is required for immunity against Plasmodium and bacteria

October 2, 2018 - 16:35 -- Open Access
Author(s): 
Ana C. Bahia, Marina S. Kubota, Yara M. Traub-Csekö, et al.
Reference: 
PLoS Negl Trop Dis 12(9): e0006785

Innate immunity is an ancient and conserved defense system that provides an early effective response against invaders.

NOT Open Access | Malaria parasite translocon structure and mechanism of effector export

September 11, 2018 - 14:53 -- NOT Open Access
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Author(s): 
Chi-Min Ho, Josh R. Beck, Mason Lai, Yanxiang Cui, Daniel E. Goldberg, Pascal F. Egea & Z. Hong Zhou
Reference: 
Nature volume 561, pages70–75 (2018)

The putative Plasmodium translocon of exported proteins (PTEX) is essential for transport of malarial effector proteins across a parasite-encasing vacuolar membrane into host erythrocytes, but the mechanism of this process remains unknown.

Avian malaria co-infections confound infectivity and vector competence assays of Plasmodium homopolare

July 26, 2018 - 16:14 -- Open Access
Author(s): 
Jenny S. Carlson, Brittany Nelms, Christopher M. Barker, William K. Reisen, Ravinder N. M. Sehgal & Anthony J. Cornel
Reference: 
Parasitology Research August 2018, Volume 117, Issue 8, pp 2385–2394

Currently, there are very few studies of avian malaria that investigate relationships among the host-vector-parasite triad concomitantly.

Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments

July 19, 2018 - 16:52 -- Open Access
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Author(s): 
Ross G. Douglas, Prajwal Nandekar, Friedrich Frischknecht, et al.
Reference: 
PLoS Biol 16(7): e2005345

Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments.

NOT Open Access | Combination of artemisinin-based natural compounds from Artemisia annua L. for the treatment of malaria: Pharmacodynamic and pharmacokinetic studies

July 6, 2018 - 14:27 -- NOT Open Access
Author(s): 
Jing Li, Chao Zhang, Muxin Gong and Manyuan Wang
Reference: 
Phytotherapy Research banner Volume32, Issue7 July 2018 Pages 1415-1420

Currently, the most effective antimalarial is artemisinin, which is extracted from the leaves of medicinal herb Artemisia annua L. (A. annua).

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NOT Open Access | Can Wolbachia modulate the fecundity costs of Plasmodium in mosquitoes?

July 3, 2018 - 16:30 -- NOT Open Access
Tags: 
Author(s): 
F Zélé, J Denoyelle, O Duron and A Rivero
Reference: 
Parasitology, Volume 145 / Issue 6, May 2018, pp 770 – 774

Although Wolbachia-infected mosquitoes fare overall better than uninfected ones, Wolbachia does not confer a sufficiently high reproductive boost to mosquitoes to compensate for the reproductive losses inflicted by Plasmodium.

Paleopathological Considerations on Malaria Infection in Korea before the 20th Century

May 10, 2018 - 15:48 -- Open Access
Author(s): 
Dong Hoon Shin, Min Seo, Jong Ha Hong, and Eunju Lee
Reference: 
BioMed Research International, Volume 2018, Article ID 8516785, 14 pages

In this article, we first review the history of malarial infection in Korea by means of studies on Joseon documents and the related scientific data on the evolutionary history of P. vivax in Asia. 

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Molecular approaches to determine the multiplicity of Plasmodium infections

April 24, 2018 - 15:31 -- Open Access
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Author(s): 
Daibin Zhong, Cristian Koepfli, Liwang Cui and Guiyun Yan
Reference: 
Malaria Journal 2018 17:172, 23 April 2018

Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the number of genetically distinct parasite strains co-infecting a single host, which is an important indicator of malaria epidemiology.

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