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plasmodium

NOT Open Access | The risk of malaria infection for travelers visiting the Brazilian Amazonian region: A mathematical modeling approach

August 10, 2020 - 16:14 -- NOT Open Access
Author(s): 
Massad E, Laporta GZ, Conn JE, Chaves LS, Bergo ES, Guimarães Figueira EA, Bezerra Coutinho FA, Lopez LF, Struchiner C, Mureb Sallum MA
Reference: 
Travel Med Infect Dis. 2020 Aug 6:101792

Human mobility between malaria endemic and malaria-free areas can hinder control and elimination efforts in the Amazon basin, maintaining Plasmodium circulation and introduction to new areas.

Not Open Access | Under the Radar: Epidemiology of Plasmodium ovale in the Democratic Republic of the Congo

August 10, 2020 - 15:56 -- NOT Open Access
Author(s): 
Mitchell CL, Brazeau NF, Keeler C, Mwandagalirwa MK, Tshefu AK, Juliano JJ, Meshnick SR
Reference: 
J Infect Dis. 2020 Aug 7:jiaa478

Plasmodium ovale is an understudied malaria species prevalent throughout much of sub-Saharan Africa. Little is known about the distribution of ovale malaria and risk factors associated with infection in areas of high malaria endemicity.

Cerebral and Plasmodium ovale Malaria in Rhode Island

August 5, 2020 - 16:25 -- Open Access
Author(s): 
Kaine J, Moran-Guiati J, Tanch J, Clyne B
Reference: 
R I Med J (2013). 2020 Aug 3; 103(6):64-67

We report two cases of malaria diagnosed in Rhode Island. First, a 21-year-old female who presented with 5 days of fevers, chills, headache, and myalgias after returning from a trip to Liberia, found to have uncomplicated malaria due to P. ovale which was treated successfully with atovaquone/proguanil and primaquine.

Heparin Administered to Anopheles in Membrane Feeding Assays Blocks Plasmodium Development in the Mosquito

August 5, 2020 - 16:24 -- Open Access
Author(s): 
Lantero E, Fernandes J, Aláez-Versón CR, Gomes J, Silveira H, Nogueira F, Fernàndez-Busquets X
Reference: 
Biomolecules. 2020 Aug 1;10(8):E1136

Innovative antimalarial strategies are urgently needed given the alarming evolution of resistance to every single drug developed against Plasmodium parasites. The sulfated glycosaminoglycan heparin has been delivered in membrane feeding assays together with Plasmodium berghei-infected blood to Anopheles stephensi mosquitoes.

Method for Malaria Diagnosis Based on Extractions of Samples Using Non-Invasive Techniques: An Opportunity for the Nursing Clinical Practice

August 5, 2020 - 16:17 -- Open Access
Author(s): 
Gómez-Luque A, Parejo JC, Clavijo-Chamorro MZ, López-Espuela F, Munyaruguru F, Belinchón Lorenzo S, Monroy I, Gómez-Nieto LC
Reference: 
Int J Environ Res Public Health. 2020 Jul 31;17(15):E5551

Malaria has been for millennia one of the best known and most destructive diseases affecting humans. Its high impact has aroused great interest for the development of new effective and reliable diagnostic techniques. Recently it has been recently published that hairs from mammal hosts are able to capture, hold and finally remove foreign DNA sequences of Leishmania parasites.

NOT Open Access | Plasmodium chabaudi-infected mice spleen response to synthesized silver nanoparticles from Indigofera oblongifolia extract

August 5, 2020 - 16:13 -- NOT Open Access
Author(s): 
Al-Quraishy S, Murshed M, Delic D, Al-Shaebi EM, Qasem MAA, Mares MM, Dkhil MA
Reference: 
Lett Appl Microbiol. 2020 Aug 4

Malaria is a worldwide serious-threatening infectious disease caused by Plasmodium and the parasite resistance to antimalarial drugs has confirmed a significant obstacle to novel therapeutic antimalarial drugs. In this article, we assessed the antioxidant and anti-inflammatory activity of nanoparticles prepared from Indigofera oblongifolia extract (AgNPs) against the infection with Plasmodium chabaudi caused in mice spleen.

Organoarsenic Compounds with In Vitro Activity against the Malaria Parasite Plasmodium falciparum

August 5, 2020 - 16:11 -- Open Access
Author(s): 
Basova S, Wilke N, Koch JC, Prokop A, Berkessel A, Pradel G, Ngwa CJ
Reference: 
Biomedicines. 2020 Aug 2;8(8):E260

The rapid development of parasite drug resistance as well as the lack of medications targeting both the asexual and the sexual blood stages of the malaria parasite necessitate the search for novel antimalarial compounds. Eleven organoarsenic compounds were synthesized and tested for their effect on the asexual blood stages and sexual transmission stages of the malaria parasite Plasmodium falciparum using in vitro assays.

Spatial and Temporal Patterns of Malaria in Phu Yen Province, Vietnam, from 2005 to 2016

August 5, 2020 - 16:09 -- Open Access
Author(s): 
Wangdi K, Canavati S, Duc TN, Nguyen TM, Tran LK, Kelly GC, Martin NJ, Clements ACA
Reference: 
J Trop Med Hyg. 2020 Aug 3

Malaria in Vietnam has become focal to a few provinces, including Phu Yen. This study aimed to assess correlations between intervention (population proportion protected by insecticide-treated nets and indoor residual spraying) and climatic variables with malaria incidence in Phu Yen Province. The Vietnam National Institute of Malariology, Parasitology, and Entomology provided incidence data for Plasmodium falciparum and Plasmodium vivax for 104 communes of Phu Yen Province from January 2005 to December 2016.

Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys

August 5, 2020 - 14:21 -- Open Access
Author(s): 
Aunin E, Böhme U, Sanderson T, Simons ND, Goldberg TL, Ting N, Chapman CA, Newbold CI, Berriman M, Reid AJ
Reference: 
PLoS Pathog 16(8): e1008717

Hepatocystis is a genus of single-celled parasites infecting, amongst other hosts, monkeys, bats and squirrels. Although thought to have descended from malaria parasites (Plasmodium spp.), Hepatocystis spp. are thought not to undergo replication in the blood–the part of the Plasmodium life cycle which causes the symptoms of malaria. Furthermore, Hepatocystis is transmitted by biting midges, not mosquitoes.

NOT Open Access | Virus-like particles expressing Plasmodium berghei MSP-8 induce protection against P. berghei infection

August 5, 2020 - 14:10 -- NOT Open Access
Author(s): 
Lee SH, Chu KB, Kang HJ, Basak S, Kim MJ, Park H, Jin H, Moon EK, Quan FS
Reference: 
Parasite Immunol. 2020 Aug 1:e12781

Merozoite surface protein 8 (MSP‐8) of Plasmodium parasites play an important role in erythrocyte invasion and is a potential malaria vaccine candidate.

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