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plasmodium

Interactions between Asaia, Plasmodium and Anopheles: new insights into mosquito symbiosis and implications in Malaria Symbiotic Control

June 28, 2013 - 18:16 -- Open Access
Author(s): 
Capone A, Ricci I, Damiani C, Mosca M, Rossi P, Scuppa P, Crotti E, Epis S, Angeletti M, Valzano M, Sacchi L, Bandi C, Daffonchio D, Mandrioli M, Favia G
Reference: 
Parasites & Vectors 2013, 6:182 (18 June 2013)
MalariaWorld

We have provided important information about the relationship of Asaia with both Plasmodium and Anopheles.

Host immune constraints on malaria transmission: insights from population biology of within-host parasites

June 19, 2013 - 20:37 -- Open Access
Author(s): 
McQueen PG, Williamson KC, McKenzie FE
Reference: 
Malaria Journal 2013, 12:206 (15 June 2013)
MalariaWorld

This report consists of a theoretical population biology-based analysis to determine constraints that host immunity impose upon gametocyte population growth.

Asymptomatic Plasmodium Infection and Cognition among Primary Schoolchildren in a High Malaria Transmission Setting in Uganda

June 6, 2013 - 15:49 -- Open Access
Author(s): 
Joaniter Nankabirwa, Bonnie Wandera, Noah Kiwanuka, Sarah G. Staedke, Moses R. Kamya and Simon J. Brooker
Reference: 
Am J Trop Med Hyg 2013 88:1102-1108
MalariaWorld

To investigate associations between asymptomatic parasitemia, anemia, and cognition among primary schoolchildren living in a high malaria transmission setting, we studied 740 children enrolled in a clinical trial in Tororo, Uganda.

Country: 

Not Open Access | AP-1/Fos-TGase2 Axis Mediates Wounding-induced Plasmodium falciparum Killing in Anopheles gambiae

June 3, 2013 - 16:33 -- NOT Open Access
Author(s): 
Sandrine E. Nsango, Julien Pompon, Ting Xie, Annika Rademacher, Malou Fraiture, Martine Thoma, Parfait H. Awono-Ambene, Roger S. Moyou, Isabelle Morlais and Elena A. Levashina
Reference: 
The Journal of Biological Chemistry, 288, 16145-16154
MalariaWorld

Here, using genome-wide transcriptional profiling, bioinformatics, and functional gene analysis, we identify a new axis of mosquito resistance to monoclonal Plasmodium falciparum infections that includes the AP-1 transcription factor Fos and the transglutaminase 2 (TGase2), a cross-linking enzyme with known roles in wound responses.

Laboratory diagnosis of malaria: conventional and rapid diagnostic methods

June 3, 2013 - 16:21 -- Open Access
Author(s): 
Wilson ML.
Reference: 
Arch Pathol Lab Med. 2013 Jun;137(6):805-11.
MalariaWorld

To review the current literature regarding diagnostic methods available to detect clinical malaria, with an emphasis on comparing the strengths and limitations of each method.

New insights into the protective power of platelets in malaria infection.

May 29, 2013 - 16:36 -- Open Access
Author(s): 
McMorran BJ, Burgio G, Foote SJ.
Reference: 
Commun Integr Biol. 2013 May 1;6(3)
MalariaWorld

We previously reported that platelets protect during malaria infection by binding Plasmodium-infected erythrocytes (IE) and killing the parasite within.

Not Open Access | Plasmodium rhoptry proteins: why order is important

May 15, 2013 - 16:51 -- NOT Open Access
Author(s): 
Natalie A. Counihan, Ming Kalanon, Ross L. Coppel, Tania F. de Koning-Ward
Reference: 
Trends in Parasitology, Volume 29, Issue 5, May 2013, Pages 228-236
MalariaWorld

Here we discuss recent work that has advanced our knowledge of rhoptry protein trafficking and function, and highlight areas of research that require further investigation.

Identification of Targets of CD8+ T Cell Responses to Malaria Liver Stages by Genome-wide Epitope Profiling

May 14, 2013 - 12:22 -- Open Access
Author(s): 
Julius Clemence R. Hafalla, Karolis Bauza, Johannes Friesen, Gloria Gonzalez-Aseguinolaza, Adrian V. S. Hill, Kai Matuschewski
Reference: 
PLoS Pathog 9(5): e1003303
MalariaWorld

CD8+ T cells mediate immunity against Plasmodium liver stages.

False Positivity of Non-Targeted Infections in Malaria Rapid Diagnostic Tests: The Case of Human African Trypanosomiasis

April 30, 2013 - 07:15 -- Open Access
Author(s): 
Philippe Gillet, Dieudonné Mumba Ngoyi, Albert Lukuka, Viktor Kande, Benjamin Atua, Johan van Griensven, Jean-Jacques Muyembe, Jan Jacobs, Veerle Lejon
Reference: 
PLoS Negl Trop Dis 7(4): e2180.
MalariaWorld

Specificity of some malaria RDT products in HAT was surprisingly low, and constitutes a risk for misdiagnosis of a fatal but treatable infection.

Medical Treatment: 

Not Open Access | A T-cell response to a liver-stage Plasmodium antigen is not boosted by repeated sporozoite immunizations

April 11, 2013 - 08:11 -- NOT Open Access
Author(s): 
Sean C. Murphy, Arnold Kas, Brad C. Stone, and Michael J. Bevan
Reference: 
PNAS April 9, 2013 vol. 110 no. 15 6055-6060
MalariaWorld

Development of an antimalarial subunit vaccine inducing protective cytotoxic T lymphocyte (CTL)-mediated immunity could pave the way for malaria eradication.

Medical Treatment: 

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