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plasmodium infection

NOT Open Access | B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection

February 17, 2020 - 12:05 -- NOT Open Access
Author(s): 
Arroyo EN, Pepper M
Reference: 
J Exp Med. 2020 Feb 3;217(2). pii: e20190849

CD4+ T follicular helper (Tfh) cells dominate the acute response to a blood-stage Plasmodium infection and provide signals to direct B cell differentiation and protective antibody expression.

Correction to: Occurrence and seasonal variation of human Plasmodium infection in Punjab Province, Pakistan

January 14, 2020 - 10:21 -- Open Access
Author(s): 
Qureshi NA, Fatima H, Afzal M, Khattak AA, Nawaz MA
Reference: 
BMC Infect Dis. 2020 Jan 8; 20(1):25

After publication of the original article [1], we were notified that an author’s name has been erroneously spelled. Aamir Ali Khattak should be replaced with Aamer Ali Khattak.

NOT Open Access | Reactivation of Plasmodium infection during a treatment with Infliximab: a case report

November 26, 2019 - 13:34 -- NOT Open Access
Author(s): 
Haeseleer C, Martiny D, Van Laethem Y, Cantinieaux B, Martin C.
Reference: 
International Journal of Infectious Diseases, 20 November 2019

We describe a symptomatic Plasmodium falciparum infection in a 29-year-old Guinean man receiving Infliximab since one year and without recent travel. The reactivation of submicroscopic malaria following the inhibition of TNF-alpha by infliximab is suspected.

Occurrence and seasonal variation of human Plasmodium infection in Punjab Province, Pakistan

November 8, 2019 - 16:47 -- Open Access
Author(s): 
Naveeda Akhtar Qureshi, Huma Fatima, Muhammad Afzal, Aamir Ali Khattak & Muhammad Ali Nawaz
Reference: 
BMC Infectious Diseases 19, Article number: 935 (2019)

Malaria is the fifth leading cause of death worldwide. Pakistan is considered as a moderate malaria-endemic country but still, 177 million individuals are at risk of malaria. Roughly 60% of Pakistan’s population, live in malaria-endemic regions. The present study is based upon the survey of various health care centers in 10 major cities of Northern and Southern Punjab to find out the malarial infection patterns in 2015. The diagnosis, seasonal variations, age and gender-wise distribution of Plasmodium spp. circulating in the study area were also included in the objectives.

Medical Condition: 

Introgression between Anopheles gambiae and Anopheles coluzzii in Burkina Faso and its associations with kdr resistance and Plasmodium infection

April 14, 2019 - 16:37 -- Open Access
Author(s): 
Mark J. Hanemaaijer, Hannah Higgins, Ipek Eralp, Youki Yamasaki, Norbert Becker, Oscar D. Kirstein, Gregory C. Lanzaro and Yoosook Lee
Reference: 
Malaria Journal 2019 18:127, 11 April 2019

This paper is the first report providing divergence island SNP genotypes for natural population of Burkina Faso and corresponding Plasmodium infection rates.

Country: 

Non-invasive surveillance of Plasmodium infection by real-time PCR analysis of ethanol preserved faeces from Ugandan school children with intestinal schistosomiasis

April 4, 2019 - 15:36 -- Open Access
Author(s): 
Hajri Al-Shehri, B. Joanne Power, J. Russell Stothard, et al.
Reference: 
Malaria Journal 2019 18:109, 1 April 2019

In this high transmission setting, EPF sampling with rtPCR analysis has satisfactory diagnostic performance in estimation of mean prevalence and prevalence by school upon direct comparison with POC-RDTs.

Country: 
Medical Treatment: 

Not Open Access | Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection

July 26, 2017 - 17:46 -- NOT Open Access
Author(s): 
David S. Khoury, Deborah Cromer, Miles P. Davenport, et al.
Reference: 
PNAS July 18, 2017 vol. 114 no. 29 7701-7706

Severe malaria and associated high parasite burdens occur more frequently in humans lacking robust adaptive immunity to Plasmodium falciparum.

NOT Open Access | Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations

June 21, 2017 - 15:40 -- NOT Open Access
Author(s): 
Maxmillian Mpina, Nicholas J. Maurice, Martin Prlic, et al.
Reference: 
The Journal of Immunology, Vol. 199, Issue 1, 1 Jul 2017

Animal model studies highlight the role of innate-like lymphocyte populations in the early inflammatory response and subsequent parasite control following Plasmodium infection.

Not Open Access | Platelets activate a pathogenic response to blood-stage Plasmodium infection but not a protective immune response

April 18, 2017 - 15:26 -- NOT Open Access
Author(s): 
Irene Gramaglia, Joyce Velez, Valery Combes, Georges E. R. Grau, Melanie Wree, and Henri C. van der Heyde
Reference: 
Blood 129, Volume: 129, Issue: 12, Pages: 1669-1679

Clinical studies indicate that thrombocytopenia correlates with the development of severe falciparum malaria, suggesting that platelets either contribute to control of parasite replication, possibly as innate parasite killer cells or function in eliciting pathogenesis.

Anti-malarial activity of a polyherbal product (Nefang) during early and established Plasmodium infection in rodent models

December 5, 2014 - 07:22 -- Open Access
Author(s): 
Protus Arrey Tarkang, Faith A Okalebo, Lawrence S Ayong, Gabriel A Agbor, Anastasia N Guantai
Reference: 
Malaria Journal 2014, 13:456 (25 November 2014)

This study aimed at investigating the suppressive, prophylactic and curative activities of Nefang in Plasmodium infected rodent models.

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