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Artesunate/Amodiaquine Malaria Treatment for Equatorial Guinea (Central Africa)

June 6, 2013 - 15:41 -- Open Access
Pilar Charle, Pedro Berzosa, Aida de Lucio, José Raso, Gloria Nseng Nchama and Agustín Benito
Am J Trop Med Hyg 2013 88:1087-1092

Our study showed the good efficacy of combination AS/AQ therapy. This finding enabled this treatment to be recommended to Equatorial Guinea's National Malaria Control Program to change the official treatment policy as of March 2008.

NOT Open Access | Novel in vivo active anti-malarials based on a hydroxy-ethyl-amine scaffold

January 22, 2013 - 07:52 -- NOT Open Access
Claire-Lise Ciana, Romain Siegrist, Christoph Boss, et al.
Bioorganic & Medicinal Chemistry Letters, Volume 23, Issue 3, 1 February 2013, Pages 658–662

A novel series of anti-malarials, based on a hydroxy-ethyl-amine scaffold, initially identified as peptidomimetic protease inhibitors is described.

A lactate dehydrogenase ELISA-based assay for the in vitro determination of Plasmodium berghei sensitivity to anti-malarial drugs

November 12, 2012 - 08:55 -- Open Access
Orjuela-Sánchez P, Duggan E, Nolan J, Frangos JA, Carvalho LJ
Malaria Journal 2012, 11:366 (5 November 2012)

This ELISA-based in vitro drug assay is easy to implement, fast, and avoids the use radioisotopes or expensive equipment.

Medical Treatment: 


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