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plasmodium spp.

NOT Open Access | Kerteszia cruzii and extra-Amazonian malaria in Brazil: Challenges due to climate change in the Atlantic Forest

July 16, 2020 - 07:56 -- NOT Open Access
de Azevedo TS, Lorenz C, Chiaravalloti-Neto F, Sallum MAM
Infect Genet Evol. 2020 Jul 12:104456

Kerteszia cruzii is a sylvatic mosquito and the primary vector of Plasmodium spp., which can cause malaria in humans in areas outside the Amazon River basin in Brazil. Anthropic changes in the natural environments are the major drivers of massive deforestation and local climate change, with serious impacts on the dynamics of mosquito communities and on the risk of acquiring malaria.

Plasmodium spp. mixed infection leading to severe malaria: a systematic review and meta-analysis

July 8, 2020 - 15:36 -- Open Access
Kotepui M, Kotepui KU, De Jesus Milanez G, Masangkay FR
Sci Rep. 2020 Jul 6;10(1):11068

Mixed Plasmodium malaria infections can lead to severe malaria. This systematic review and meta-analysis aimed to explore the prevalence of severe mixed Plasmodium malaria infection and to compare it with the prevalence of severe P. falciparum malaria mono-infection across the included studies. Original English-language research articles from PubMed, Scopus, and ISI Web of Science were identified and screened.

Different distribution of malaria parasite in left and right extremities of vertebrate hosts translates into differences in parasite transmission

June 26, 2020 - 12:00 -- Open Access
Pigeault R, Isaïa J, Yerbanga RS, Dabiré KR, Ouédraogo JB, Cohuet A, Lefèvre T, Christe P
Sci Rep. 2020 Jun 23;10(1):10183

Malaria, a vector-borne disease caused by Plasmodium spp., remains a major global cause of mortality. Optimization of disease control strategies requires a thorough understanding of the processes underlying parasite transmission. While the number of transmissible stages (gametocytes) of Plasmodium in blood is frequently used as an indicator of host-to-mosquito transmission potential, this relationship is not always clear. Significant effort has been made in developing molecular tools that improve gametocyte density estimation and therefore prediction of mosquito infection rates.

Prevalence and proportion of Plasmodium spp. triple mixed infections compared with double mixed infections: a systematic review and meta-analysis

June 26, 2020 - 11:09 -- Open Access
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez and Frederick R. Masangkay
Malaria Journal 2020 19:224, 24 June 2020

Although mixed infection by two Plasmodium species has been recognized, mixed infection by three different Plasmodium species within one individual has not been clarified. This study sought to determine the pooled prevalence and proportion of triple mixed Plasmodium spp. infection compared with double mixed infection.

Diagnosis of Malaria Parasites Plasmodium spp. in Endemic Areas: Current Strategies for an Ancient Disease

December 23, 2019 - 14:25 -- Open Access
Gitta B, Kilian N
Bioessays, 2019 Dec 12:e1900138

Fast and effective detection of the causative agent of malaria in humans, protozoan Plasmodium parasites, is of crucial importance for increasing the effectiveness of treatment and to control a devastating disease that affects millions of people living in endemic areas. The microscopic examination of Giemsa‐stained blood films still remains the gold‐standard in Plasmodium detection today.

Prevalence of Plasmodium spp. in the Amazonian Border Context (French Guiana-Brazil): Associated Factors and Spatial Distribution

November 27, 2019 - 16:08 -- Open Access
Mosnier E, Roux E, Musset L, et al.
Am. J. Trop. Med. Hyg., 00(0), 2019, pp. 1–12

To implement future malaria elimination strategies in French Guiana, a characterization of the infectious reservoir is recommended. A cross-sectional survey was conducted between October and December 2017 in the French Guianese municipality of St Georges de l’Oyapock, located along the Brazilian border. The prevalence of Plasmodium spp. was determined using a rapid diagnostic test (RDT) and a polymerase chain reaction (PCR).


Assessment of asymptomatic Plasmodium spp. infection by detection of parasite DNA in residents of an extra-Amazonian region of Brazil

March 15, 2018 - 07:01 -- Open Access
Filomena E. C. de Alencar, Rosely dos Santos Malafronte, Angelica Espinosa Miranda, et al.
Malaria Journal 2018 17:113, 14 March 2018

The low incidence of cases and the low frequency of asymptomatic malaria carriers investigated make it unlikely that the transmission chain in the region is based solely on human hosts, as cases are isolated one from another by hundreds of kilometers and frequently by long periods of time, reinforcing instead the hypothesis of zoonotic transmission.

Phylogenetic analysis of simian Plasmodium spp. infecting Anopheles balabacensis Baisas in Sabah, Malaysia

October 12, 2017 - 15:24 -- Open Access
Tock H. Chua, Benny O. Manin, Sylvia Daim, Indra Vythilingam, Chris Drakeley
PLoS Negl Trop Dis 11(10): e0005991


Anopheles balabacensis of the Leucospyrus group has been confirmed as the primary knowlesi malaria vector in Sabah, Malaysian Borneo for some time now. Presently, knowlesi malaria is the only zoonotic simian malaria in Malaysia with a high prevalence recorded in the states of Sabah and Sarawak.

Methodology/Principal findings


NOT Open Access | Development of a rapid HRM qPCR for the diagnosis of the four most prevalent Plasmodium lineages in New Zealand

June 27, 2017 - 18:06 -- NOT Open Access
E. R. Schoener, S. Hunter & L. Howe
Parasitology Research, July 2017, Volume 116, Issue 7, pp 1831–1841

Although wildlife rehabilitation and translocations are important tools in wildlife conservation in New Zealand, disease screening of birds has not been standardized.


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