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parasitemia

Pediatric cerebral malaria: a scourge of Africa

December 19, 2012 - 11:44 -- Open Access
Author(s): 
Douglas G Postels, Yamikani F Chimalizeni, Macpherson Mallewa, Michael J Boivin & Karl B Seydel
Reference: 
Future Neurology, January 2013, Vol. 8, No. 1, Pages 67-85
MalariaWorld

Although adjunctive therapy trials continue, the best hope for African children may lie in disease prevention. Strategies include bednets, chemoprophylaxis and vaccine development.

Interactions and Potential Implications of Plasmodium falciparum-Hookworm Coinfection in Different Age Groups in South-Central Côte d'Ivoire

November 12, 2012 - 08:14 -- Open Access
Author(s): 
Aurélie A. Righetti, Dominik Glinz, Lukas G. Adiossan, Ahou-Yah G. Koua, Sébastien Niamké, Richard F. Hurrell, Rita Wegmüller, Eliézer K. N'Goran, Jürg Utzinger
Reference: 
PLoS Negl Trop Dis 6(11): e1889
MalariaWorld

Our findings suggest that interaction between P. falciparum and light-intensity hookworm infections vary with age and, in school-aged children, may benefit the host through preventing iron deficiency anemia.

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Filariasis Attenuates Anemia and Proinflammatory Responses Associated with Clinical Malaria: A Matched Prospective Study in Children and Young Adults

November 12, 2012 - 07:57 -- Open Access
Author(s): 
Housseini Dolo, Yaya I. Coulibaly, Amy D. Klion, et al.
Reference: 
PLoS Negl Trop Dis 6(11): e1890
MalariaWorld

These data suggest that pre-existent filarial infection attenuates immune responses associated with severe malaria and protects against anemia, but has little effect on susceptibility to or severity of acute malaria infection.

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