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parasitemia

Effect of chronic khat (Catha edulis, Forsk) use on outcome of Plasmodium berghei ANKA infection in Swiss albino mice

April 7, 2015 - 15:34 -- Open Access
Author(s): 
Tsige Ketema, Moti Yohannes, Esayas Alemayehu and Argaw Ambelu
Reference: 
BMC Infectious Diseases 2015, 15:170

The finding of this study showed that khat use was strongly associated with increment of levels of liver and kidney biomarkers, leucopenia, severe anemia, rise in level of inflammation biomarkers: C-reactive protein (CRP), uric acid (UA), increased monocyte-lymphocyte count ratio (MLCR), manifestation of cerebral malaria symptoms such as ataxia, paralysis and deviation of the head but with no pulmonary edema.

Randomized Controlled Trial of Levamisole Hydrochloride as Adjunctive Therapy in Severe Falciparum Malaria With High Parasitemia

December 17, 2013 - 19:06 -- Open Access
Author(s): 
Richard J. Maude, Kamolrat Silamut, Arjen M. Dondorp, et al.
Reference: 
Clin Infect Dis. (2014) 58 (1): 11-21.

Cytoadherence and sequestration of erythrocytes containing mature stages of Plasmodium falciparum are central to the pathogenesis of severe malaria.

Not Open Access | Genetic characterization of Plasmodium falciparum allelic variants infecting mothers at delivery and their children during their first plasmodial infections

October 16, 2013 - 18:43 -- NOT Open Access
Author(s): 
Célia Dechavanne, Charlotte Pierrat, Florence Migot-Nabias, et al.
Reference: 
Infection, Genetics and Evolution, Volume 20, December 2013, Pages 16-25
MalariaWorld

The hypothesis of this study is that this increased susceptibility might be related to infections by parasites expressing the same blood stage allele’s antigens as those to which the infants were exposed in utero.

VAR2CSA Signatures of High Plasmodium falciparum Parasitemia in the Placenta

August 5, 2013 - 15:36 -- Open Access
Author(s): 
Eduard Rovira-Vallbona, Isadora Monteiro, Alfredo Mayor, et al.
Reference: 
PLoS ONE 8(7): e69753.
MalariaWorld

These results suggest that a higher binding efficiency to CSA rather than reduced antigenicity might provide a biological advantage to parasites with high parasite density signatures in VAR2CSA.

Home- or community-based programmes for treating malaria.

June 10, 2013 - 14:52 -- Open Access
Author(s): 
Okwundu CI, Nagpal S, Musekiwa A, Sinclair D.
Reference: 
Cochrane Database Syst Rev. 2013 May 31;5
MalariaWorld

Randomized controlled trials (RCTs) and non-RCTs that evaluated the effects of a home- or community-based programme for treating malaria in a malaria endemic setting.

Not Open Access | Impact of Indoor Residual Spraying of Lambda-Cyhalothrin on Malaria Prevalence and Anemia in an Epidemic-Prone District of Muleba, North-Western Tanzania

May 6, 2013 - 16:19 -- NOT Open Access
Author(s): 
Fabian M. Mashauri, Safari M. Kinung'hi, Godfrey M. Kaatano, Stephen M. Magesa, Coleman Kishamawe, Joseph R. Mwanga, Soori E. Nnko, Robert C. Malima, Chacha N. Mero, and Leonard E. G. Mboera
Reference: 
Am J Trop Med Hyg 2013 88:841-849
MalariaWorld

The Government of Tanzania introduced indoor residual spraying (IRS) in Muleba district in north-western Tanzania after frequent malaria epidemics.

Preconditioning with Hemin Decreases Plasmodium chabaudi adami Parasitemia and Inhibits Erythropoiesis in BALB/c Mice

February 11, 2013 - 18:08 -- Open Access
Author(s): 
Esther Dalko, Véronique Gaudreault, Jaime Sanchez Dardon, Robert Moreau, Tatiana Scorza
Reference: 
PLoS ONE 8(1): e54744
MalariaWorld

Herein, we investigated the impact of heme (hemin) administration on immune parameters and steady state erythropoiesis in BALB/c mice, and on parasitemia and anemia during Plasmodium chabaudi adami infection.

Evaluation of the Performances of Two Rapid Diagnostic Tests (Cyscope®mini and Paracheck-Pf®) in the Diagnosis of Malaria among Febrile Children in Southwest Nigeria

February 5, 2013 - 16:35 -- Open Access
Author(s): 
Rabiu O.R. • Kosoko A.M. • Falade C.O. • Ademowo O.G.
Reference: 
Med Princ Pract
MalariaWorld

 The aim of this study was to test the diagnostic performances of Cyscope®mini and Paracheck-Pf® for Plasmodium falciparum relative to microscopy.

Not Open Access | Evidence and Implications of Mortality Associated with Acute Plasmodium vivax Malaria

January 9, 2013 - 14:55 -- NOT Open Access
Author(s): 
J. Kevin Baird
Reference: 
Clin. Microbiol. Rev. January 2013 vol. 26 no. 1 36-57
MalariaWorld

The very well-documented course of this infection, with the exception of parasitemia, carries all of the attributes of “perniciousness” historically linked to falciparum malaria, including severe disease and fatal outcomes.

NOT Open Access | Substantiation of the ethnopharmacological use of Conyza sumatrensis (Retz.) E.H.Walker in the treatment of malaria through in-vivo evaluation in Plasmodium berghei infected mice

January 8, 2013 - 12:54 -- NOT Open Access
Author(s): 
Pone Kamdem Boniface, Anirban Pal
Reference: 
Journal of Ethnopharmacology, Volume 145, Issue 1, 9 January 2013, Pages 373-377
MalariaWorld

Our study has tried to address this gap by authenticating its traditional use for the treatment of malaria.

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