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Artesunate-amodiaquine efficacy in Congolese children with acute uncomplicated falciparum malaria in Brazzaville

February 11, 2013 - 16:29 -- Open Access
Ndounga M, Mayengue P, Casimiro P, Loumouamou D, Basco LK, Ntoumi F, Brasseur P
Malaria Journal 2013, 12:53 (5 February 2013)

This study has shown the high efficacy of AS + AQ in Congolese patients of all ages with acute uncomplicated falciparum malaria and serves as the baseline efficacy and tolerance of this ACT in Brazzaville.

Medical Condition: 

Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial

November 12, 2012 - 07:38 -- Open Access
Kayentao K, Doumbo OK, Fleckenstein L, et al.
Malaria Journal 2012, 11:364 (31 October 2012)

Following the recent successes of malaria control in sub-Saharan Africa, the gametocytocidal drug primaquine needs evaluation as a tool to further reduce the transmission of Plasmodium falciparum malaria. The drug has scarcely been used in Africa because of concerns about its safety in people with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The evidence base for the use of primaquine as a transmission blocker is limited by a lack of comparable clinical and parasitological endpoints between trials.

Medical Treatment: 


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