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plasmodium falciparum

Not Open Access | Plasmodium: Yet More Don’ts

February 9, 2019 - 18:51 -- NOT Open Access
Miles B. Markus
Trends in Parasitology, Letter| Volume 35, Issue 2, P101-102, February 01, 2019

Anopheline’ is both an adjective (‘anopheline mosquito’) and a noun. Don’t use an upper case ‘A’, except at the beginning of a sentence; and do not italicize the word as if it is a Latinized genus name.

Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure

February 9, 2019 - 18:45 -- Open Access
Victor Yman, Michael T. White, Muhammad Asghar, Christopher Sundling, Klara Sondén, Simon J. Draper, Faith H. A. Osier and Anna Färnert
BMC Medicine 201917:22

Prospective studies of travellers with different levels of prior exposure, returning to malaria-free countries with Plasmodium infection, offer a unique opportunity to investigate the kinetics and composition of the antibody response after natural infection.


Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study

February 6, 2019 - 15:50 -- Open Access
Dorothy Wavinya Nyamai and Özlem Tastan Bishop
Malaria Journal 2019 18:34, 6 February 2019

This study showed that, despite, functional and structural conservation, Plasmodium aaRSs have key differences from the human homologues.

Genetic variability of Plasmodium falciparum histidine-rich proteins 2 and 3 in Central America

February 5, 2019 - 16:22 -- Open Access
Gustavo Fontecha, Alejandra Pinto, Denis Escobar, Gabriela Matamoros and Bryan Ortiz
Malaria Journal 2019 18:31, 31 January 2019

It is unlikely that the variability of the pfhrp2 and pfhrp3 genes has a significant impact on the ability of the RDTs to detect the PfHRP antigens in Central America.


Does artemether–lumefantrine administration affect mosquito olfactory behaviour and fitness?

January 30, 2019 - 16:08 -- Open Access
Jetske G. de Boer, Annette O. Busula, Jet ten Berge, Tessa S. van Dijk and Willem Takken
Malaria Journal 2019 18:28, 28 January 2019

Based on the results, AL does not appear to influence malaria transmission through modification of vector mosquito olfactory behaviour or fitness.

Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies

January 30, 2019 - 16:04 -- Open Access
Kristina Haeussler, Isabell Berneburg, Katja Becker, et al.
Malaria Journal 2019 18:22, 25 January 2019

The characterization of PvG6PD makes this enzyme accessible to further drug discovery activities.

Streamlined SMFA and mosquito dark-feeding regime significantly improve malaria transmission-blocking assay robustness and sensitivity

January 29, 2019 - 16:11 -- Open Access
Tibebu Habtewold, Sofia Tapanelli, Ellen K. G. Masters, Astrid Hoermann, Nikolai Windbichler and George K. Christophides
Malaria Journal 2019 18:24, 25 January 2019

A robust SMFA protocol that enhances the evaluation of interventions targeting human malaria transmission in laboratory setting is reported

Medical Condition: 

Comparative analysis of IgG and IgG subclasses against Plasmodium falciparum MSP-119 in children from five contrasting bioecological zones of Cameroon

January 22, 2019 - 15:07 -- Open Access
Tebit Emmanuel Kwenti, Tufon Anthony Kukwah, Theresa Nkuo-Akenji, et al.
Malaria Journal 2019 18:16, 22 January 2019

This study showed that antibody responses against MSP-119 vary considerably in children from the different bioecological strata in Cameroon and could be linked to the differential exposure to malaria in the different strata.


Risk of transfusion-transmitted malaria: evaluation of commercial ELISA kits for the detection of anti-Plasmodium antibodies in candidate blood donors

January 22, 2019 - 15:06 -- Open Access
Valentina D. Mangano, Francesca Perandin, Fabrizio Bruschi, et al.
Malaria Journal 2019 18:17, 22 January 2019

These preliminary results indicate how the lack of a gold standard for malaria serology must be taken into account in the application and future revision of current legislation.

An online mapping database of molecular markers of drug resistance in Plasmodium falciparum: the ACT Partner Drug Molecular Surveyor

January 22, 2019 - 14:56 -- Open Access
Sabina Dahlström Otienoburu, Ignacio Suay, Steven Garcia, Nigel V. Thomas, Suttipat Srisutham, Anders Björkman and Georgina S. Humphreys
Malaria Journal 2019 18:12, 18 January 2019

The WWARN ACT Partner Drugs Molecular Surveyor summarizes data on resistance markers in the pfmdr1 and pfcrt genes.


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