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plasmodium falciparum

Not Open Access | Epidemiological aspects of severe child anemia due to malaria in the socio-economic crisis zone at the Bangassou Regional University Hospital in Central Africa: In French

December 13, 2018 - 08:54 -- NOT Open Access
Author(s): 
E. Kalthan, A. Moboy, G. Tekpa, C.M. Pamatika, D.E.R. Nakoune, B. Kofi
Reference: 
Publié dans Médecine d'Afrique Noire 6511 - Novembre 2018 - pages 531-538

One of the major complications of malaria due to Plasmodium falciparum is hemolytic anemia. The generalized military-political crisis of 2013 in the country has led to the dysfunction of the health system, thus promoting the resurgence of cases of diseases including malaria in Bagassou. The objective of this study was to describe the epidemiological aspects of anemia during the malaria of the Child in Bangassou.

NOT Open Access | Cutting Edge: FHR-1 Binding Impairs Factor H–Mediated Complement Evasion by the Malaria Parasite Plasmodium falciparum

December 12, 2018 - 16:29 -- NOT Open Access
Author(s): 
Timo Reiss, Thiago F. de A. Rosa, Katharina Blaesius, Rebecca P. Bobbert, Peter F. Zipfel, Christine Skerka and Gabriele Pradel
Reference: 
The Journal of Immunology Vol. 201, Issue 12, 15 Dec 2018

Human complement is the first line of defense against invading pathogens, including the malaria parasite Plasmodium falciparum.

Plasmodium falciparum artemisinin resistance monitoring in Sabah, Malaysia: in vivo therapeutic efficacy and kelch13 molecular marker surveillance

December 12, 2018 - 16:07 -- Open Access
Author(s): 
Matthew J. Grigg, Timothy William, Nicholas M. Anstey, et al.
Reference: 
Malaria Journal 2018 17:463, 10 December 2018

There is no suspected or confirmed evidence of endemic artemisinin-resistant P. falciparum in this pre-elimination setting in Sabah, Malaysia.

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Genetic diversity and allele frequencies of Plasmodium falciparum msp1 and msp2 in parasite isolates from Bioko Island, Equatorial Guinea

December 11, 2018 - 16:29 -- Open Access
Author(s): 
Jiang-Tao Chen, Jian Li, Min Lin, et al.
Reference: 
Malaria Journal 2018 17:458, 7 December 2018

The present data showed high genetic diversity and MOI values among the P. falciparum population in the study, reflecting both the high endemic level and malaria transmission on Bioko Island.

Insecticide space spraying for preventing malaria transmission

December 11, 2018 - 13:32 -- Open Access
Author(s): 
Joseph Pryce, Leslie Choi, Marty Richardson, David Malone
Reference: 
Cochrane Database of Systematic Reviews2018, Issue 11.

For the review's secondary objective, we identified a further two studies in addition to the two ITS studies; both used a CBA design and were conducted between 1973 and 2000. The four studies used a range of delivery methods including handheld, vehicle‐mounted, and aircraft‐mounted spraying equipment.

Cryogenically preserved RBCs support gametocytogenesis of Plasmodium falciparum in vitro and gametogenesis in mosquitoes

December 6, 2018 - 17:05 -- Open Access
Author(s): 
Ashutosh K. Pathak, Justine C. Shiau, Matthew B. Thomas and Courtney C. Murdock
Reference: 
Malaria Journal 2018 17:457, 6 December 2018

Basic guidelines are presented for integrating cryo-preserved RBCs into an existing laboratory/insectary framework for P. falciparum SMFAs with significant potential for reducing running costs while achieving greater reliability.

Interplay between Plasmodium falciparum haemozoin and l-arginine: implication for nitric oxide production

December 6, 2018 - 17:03 -- Open Access
Author(s): 
Yolanda Corbett, Sarah D’Alessandro, Nicoletta Basilico, et al.
Reference: 
Malaria Journal 2018 17:456, 6 December 2018

It is proposed that haemozoin interacts with l-arginine reducing its availability for iNOS, and thus decreasing nitric oxide production.

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways

December 5, 2018 - 16:30 -- Open Access
Author(s): 
Susana Campino, Alejandro Marin-Menendez, Julian C. Rayner, et al.
Reference: 
PLoS Pathog 14(11): e1007436

Invasion of human erythrocytes is essential for Plasmodium falciparum parasite survival and pathogenesis, and is also a complex phenotype.

Inhibition of JNK signaling in the Asian malaria vector Anopheles stephensi extends mosquito longevity and improves resistance to Plasmodium falciparum infection

December 5, 2018 - 16:29 -- Open Access
Author(s): 
Lattha Souvannaseng, Lewis Vibul Hun, Shirley Luckhart, et al.
Reference: 
PLoS Pathog 14(11): e1007418

Malaria is a global health concern caused by infection with Plasmodium parasites.

Accuracy of One Step malaria rapid diagnostic test (RDT) in detecting Plasmodium falciparum placental malaria infection in women living in Yaoundé, Cameroon

December 5, 2018 - 15:53 -- Open Access
Author(s): 
Rosette Megnekou, Jean Claude Djontu, Benderli C. Nana, Jude D. Bigoga, Maurice Fotso, Balotin Fogang and Rose F. G. Leke
Reference: 
Malaria Journal 2018 17:450, 4 December 2018

These results depict One Step malaria HRP-II RDT to be better in detecting placental P. falciparum infection in pregnant women compared to Giemsa-stained peripheral thick blood smear.

Medical Treatment: 

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