This study is the first to report on the genetic diversity and natural selection of full-length pktrap.
These data provide support for the validation of in vitro growth inhibition assay using antibodies of DBPα and AMA1 in human-adapted P. knowlesi parasite PkA1-H.1 strain.
This is the first study to describe serological exposure to P. knowlesi and associated risk factors within endemic communities.
The PkSERA3 antigen 2 had the highest relative variable importance in all models.
Plasmodium knowlesi is primarily responsible for zoonotic malaria in several Southeast Asian countries. Precise identification of the parasite in the blood of patients presently relies on an expensive and elaborate PCR procedure because microscopic examination of blood and other available field identification techniques lack adequate specificity.
In malaria elimination areas, malaria cases are sporadic and consist predominantly of imported cases.
On July 17, 2016, a 12-year-old Laotian boy living in Bengvilay village, Sanamxay district, Attapeu province (adjacent to Cambodia) in Laos visited Bengvilay Health Center.
This study is the first to report on the genetic diversity and natural selection of pkmsp1p.
Plasmodium knowlesi is a simian malaria of primarily the macaque species of South East Asia.
Consequently, malaria research was, and still is, underpinned by the quest to understand, control and prevent malaria caused by P. falciparum.