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spatial repellent

Behavioral response of insecticide-resistant mosquitoes against spatial repellent: A modified self-propelled particle model simulation

January 1, 2021 - 16:06 -- Open Access
Zhou G, Yu L, Wang X, Zhong D, Lee MC, Kibret S, Yan G
PLoS One. 2020 Dec 29;15(12):e0244447

Rapidly increasing pyrethroid insecticide resistance and changes in vector biting and resting behavior pose serious challenges in malaria control. Mosquito repellents, especially spatial repellents, have received much attention from industry. We attempted to simulate interactions between mosquitoes and repellents using a machine learning method, the Self-Propelled Particle (SPP) model, which we modified to include attractiveness/repellency effects. We simulated a random walk scenario and scenarios with insecticide susceptible/resistant mosquitoes against repellent alone and against repellent plus attractant (to mimic a human host).

NOT Open Access | Field Evaluation of a Spatial Repellent Emanation Vest for Personal Protection Against Outdoor Biting Mosquitoes

October 21, 2020 - 09:36 -- NOT Open Access
Sukkanon C, Tisgratog R, Muenworn V, Bangs MJ, Hii J, Chareonviriyaphap T
J Med Entomol. 2020 Oct 20:tjaa213

Exophilic vectors are an important contributor to residual malaria transmission. Wearable spatial repellents (SR) can potentially provide personal protection in early evening hours before people retire indoors. An SR prototype for passive delivery of transfluthrin (TFT) for protecting humans against nocturnal mosquitoes in Kanchanaburi, western Thailand, is evaluated. A plastic polyethylene terephthalate (PET) sheet (676 cm2) treated with 55-mg TFT (TFT-PET), attached to the back of short-sleeve vest worn by human collector, was evaluated under semifield and outdoor conditions.

Efficacy of a Spatial Repellent for Control of Malaria in Indonesia: A Cluster-Randomized Controlled Trial

May 21, 2020 - 06:41 -- Open Access
Syafruddin D, Asih PBS, Achee NL, et al.
Am J Trop Med Hyg. 2020 May 18

A cluster-randomized, double-blinded, placebo-controlled trial was conducted to estimate the protective efficacy (PE) of a spatial repellent (SR) against malaria infection in Sumba, Indonesia. Following radical cure in 1,341 children aged ≥ 6 months to ≤ 5 years in 24 clusters, households were given transfluthrin or placebo passive emanators (devices designed to release vaporized chemical).

Time to give spatial repellency its rightful role in vector control

June 19, 2012 - 19:19 -- Bart G.J. Knols

The following Guest editorial was provided by Richard Tren, Kimberly Hess, and Donald Roberts.

Progress is being made against malaria. As reported by the World Health Organization (WHO), malaria cases have declined by more than 50% between 2000 and 2010, and malaria-specific mortality has declined by 26% [1].  These gains are mainly due to the use of insecticides to control disease-spreading insects (vector control) through insecticide-treated bednets and indoor residual spraying (IRS). Despite the importance of public health insecticides in vector control, there is very little appreciation and understanding of how insecticides actually work in disease prevention.

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