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NOT Open Access | How can we develop an effective subunit vaccine to achieve successful malaria eradication

September 23, 2021 - 09:00 -- NOT Open Access
Pirahmadi S, Afzali S, Zargar M, Zakeri S, Mehrizi AA
Microb Pathog. 2021 Sep 18:105203

Malaria, a mosquito-borne infection, is the most widespread parasitic disease. Despite numerous efforts to eradicate malaria, this disease is still a health concern worldwide. Owing to insecticide-resistant vectors and drug-resistant parasites, available controlling measures are insufficient to achieve a malaria-free world. Thus, there is an urgent need for new intervention tools such as efficient malaria vaccines.

NOT Open Access | The End of the Artemisinin Era-We Should Aim at Malaria Eradication in Asia Using Free, Effective Treatment

August 4, 2021 - 12:17 -- NOT Open Access
Petersen E, Picot S
Clin Infect Dis. 2021 Aug 2;73(3):414-415

No abstract available

Researchers’ perceptions of malaria eradication: findings from a mixed-methods analysis of a large online survey

October 8, 2020 - 15:19 -- Open Access
Joe Brew, Menno Pradhan, Jacqueline Broerse and Quique Bassat
Malaria Journal 2020 19:359, 8 October 2020

The value of malaria eradication, the permanent reduction to zero of the worldwide incidence of malaria infection caused by human malaria parasites, would be enormous. However, the expected value of an investment in an intended, but uncertain, outcome hinges on the probability of, and time until, its fulfilment. Though the long-term benefits of global malaria eradication promise to be large, the upfront costs and uncertainty regarding feasibility and timeframe make it difficult for policymakers and researchers to forecast the return on investment.

NOT Open Access | Maximizing Impact: Can Interventions to Prevent Clinical Malaria Reduce Parasite Transmission

September 15, 2020 - 14:30 -- NOT Open Access
McCann RS, Cohee LM, Goupeyou-Youmsi J, Laufer MK
Trends Parasitol. 2020 Sep 8:S1471-4922(20)30196-3

Malaria interventions may reduce the burden of clinical malaria disease, the transmission of malaria parasites, or both. As malaria interventions are developed and evaluated, including those interventions primarily targeted at reducing disease, they may also impact parasite transmission.

NOT Open Access | Long-lasting insecticidal nets and the quest for malaria eradication: a mathematical modeling approach

May 25, 2020 - 08:13 -- NOT Open Access
Enahoro I, Eikenberry S, Gumel AB, Huijben S, Paaijmans K
J Math Biol. 2020 May 23

Recent dramatic declines in global malaria burden and mortality can be largely attributed to the large-scale deployment of insecticidal-based measures, namely long-lasting insecticidal nets (LLINs) and indoor residual spraying. However, the sustainability of these gains, and the feasibility of global malaria eradication by 2040, may be affected by increasing insecticide resistance among the Anopheles malaria vector.

NOT Open Access | The efficacy of intermittent preventive therapy in the eradication of peripheral and placental parasitemia in a malaria-endemic environment, as seen in a tertiary hospital in Abuja, Nigeria

December 23, 2019 - 14:30 -- NOT Open Access
Umemmuo MU, Agboghoroma CO, Iregbu KC
Int J Gynaecol Obstet. 2019 Dec 12.

To determine whether intermittent preventive therapy in pregnancy (IPTp) eradicates peripheral and placental malaria and improves birth weight.

Should there be a World Health Assembly resolution for malaria eradication? Opinion against

October 28, 2019 - 16:24 -- Open Access
T. Jacob John
Malaria Journal 2019 18:353, 21 October 2019

A resolution for eradicating malaria, if passed by the World Health Assembly (WHA), will have a distracting effect on all countries with malaria. The continued prevalence of malaria is indicative of weak public health infrastructure.

Medical Condition: 

Malaria eradication within a generation: ambitious, achievable, and necessary

September 11, 2019 - 16:03 -- Open Access
Richard G A Feachem, Ingrid Chen, Winnie Mpanju-Shumbusho, et al.
The Lancet, September 08, 2019

In the first report of its kind and with a bold vision, the Commission lays the out the necessary steps, including an even greater financial outlay, strengthening malaria programmes and global leadership, and acceleration of research and development, to eradicate malaria within a generation.

Is the bednet era coming to an end?

June 22, 2012 - 12:47 -- Bart G.J. Knols

Whenever I teach on the history of malaria, I talk about the different time periods when certain ideas were fashionable and implemented, and then disappeared, and sometimes came back much later.

Take the 'chloroquine era'. Discovered by Bayer scientists in the early 1930s and saved millions of lives around the globe, followed by resistance popping up in SE Asia and Colombia in the late 1950s. Resistance spreading to Africa in the late 1970s, and its use now largely reduced. End of the 'chloroquine era'.


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