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prevalence

Data-driven malaria prevalence prediction in large densely populated urban holoendemic sub-Saharan West Africa

September 30, 2020 - 11:48 -- Open Access
Author(s): 
Brown BJ, Manescu P, Fernandez-Reyes D, et al.
Reference: 
Sci Rep. 2020 Sep 28;10(1):15918

Over 200 million malaria cases globally lead to half-million deaths annually. The development of malaria prevalence prediction systems to support malaria care pathways has been hindered by lack of data, a tendency towards universal "monolithic" models (one-size-fits-all-regions) and a focus on long lead time predictions. Current systems do not provide short-term local predictions at an accuracy suitable for deployment in clinical practice.

Potential drug–drug interactions associated with adverse clinical outcomes and abnormal laboratory findings in patients with malaria

September 1, 2020 - 10:32 -- Open Access
Author(s): 
Sidra Noor, Mohammad Ismail and Faiza Khadim
Reference: 
Malaria Journal 2020 19:316, 31 August 2020

Hospitalized patients with malaria often present with comorbidities or associated complications for which a variety of drugs are prescribed. Multiple drug therapy often leads to drug–drug interactions (DDIs). Therefore, the current study investigated the prevalence, levels, risk factors, clinical relevance, and monitoring parameters/management guidelines of potential DDIs (pDDIs) among inpatients with malaria.

Prevalence and determinants of malaria infection among children of local farmers in Central Malawi

September 1, 2020 - 09:52 -- Open Access
Author(s): 
Emmanuel Chilanga, Delphine Collin-Vézina, Heather MacIntosh, Claudia Mitchell and Katrina Cherney
Reference: 
Malaria Journal 2020 19:308, 27 August 2020

Malaria is a leading cause of morbidity and mortality among children under 5 years in Malawi, and especially among those from rural areas of central Malawi. The goal of this study was to examine the prevalence and determinants of malaria infection among children in rural areas of Dowa district in central Malawi.

A multicenter study of the prevalence and risk factors of malaria and anemia among pregnant women at first antenatal care visit in Ghana

August 25, 2020 - 07:57 -- Open Access
Author(s): 
Fondjo LA, Addai-Mensah O, Annani-Akollor ME, Quarshie JT, Boateng AA, Assafuah SE, Owiredu EW
Reference: 
PLoS One. 2020 Aug 21;15(8):e0238077

Malaria in pregnancy remains a major public health problem in Africa and Ghana and has been associated with a variety of pregnancy-related adverse complications. The development of effective and timely health policies for the prevention and control of malaria and anemia in pregnancy; requires current and consistent data on the prevalence and risk factors. We report the prevalence and risk factors of malaria and anemia from three major hospitals across three regions in Ghana.

Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania

August 24, 2020 - 14:07 -- Open Access
Author(s): 
Jacklin F. Mosha, Eliud Lukole, Natacha Protopopoff, et al.
Reference: 
Malaria Journal 2020 19:297, 20 August 2020

Long-lasting insecticidal nets (LLINs) are the most widely deployed vector control intervention in sub-Saharan Africa to prevent malaria. Recent reports indicate selection of pyrethroid insecticide resistance is widespread in mosquito vectors. This paper explores risk factors associated with malaria infection prevalence and vector density between mass distribution campaigns, changes in net coverage, and loss of protection in an area of high pyrethroid resistance in Northwest Tanzania.

Performance of IRS on malaria prevalence and incidence using pirimiphos-methyl in the context of pyrethroid resistance in Koulikoro region, Mali

August 17, 2020 - 13:22 -- Open Access
Author(s): 
Fousseyni Kané, Moussa Keïta, Boïssé Traoré, Sory Ibrahim Diawara, Sidy Bane, Souleymane Diarra, Nafomon Sogoba and Seydou Doumbia
Reference: 
Malaria Journal 2020 19:286, 12 August 2020

Koulikoro Health District is one of three districts of Mali where the indoor residual spray (IRS) has been implemented from 2008 to 2016. With widespread of resistance to pyrethroid, IRS was shifted from pyrethroid to pirimiphos-methyl from 2014 to 2016. The objective of this study was to assess the added value of IRS to LLINs on the prevalence of parasitaemia and malaria incidence among children under 10 years old.

Prevalence and associated factors of malaria among pregnant women in Sherkole district, Benishangul Gumuz regional state, West Ethiopia

August 10, 2020 - 14:38 -- Open Access
Author(s): 
Gontie GB, Wolde HF, Baraki AG
Reference: 
BMC Infect Dis. 2020 Aug 5;20(1):573

Malaria during pregnancy leads to serious adverse effects on mothers and the fetus. Approximately 25 million pregnant women in sub-Saharan Africa live at risk of malaria. This study would help to achieve Sustainable Development Goals (SDGs) by improving programs that deal with the prevention of malaria. Therefore, this study aimed to assess the prevalence and associated factors of malaria among pregnant women.

Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis

August 4, 2020 - 15:51 -- Open Access
Author(s): 
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez and Frederick R. Masangkay
Reference: 
Malaria Journal 2020 19:274, 31 July 2020

Severe complications among patients with Plasmodium malariae infection are rare. This is the first systematic review and meta-analysis demonstrating the global prevalence and mortality of severe P. malariae infection in humans.

Point prevalence of asymptomatic Plasmodium infection and the comparison of microscopy, rapid diagnostic test and nested PCR for the diagnosis of asymptomatic malaria among children under 5 years in Ghana

July 28, 2020 - 14:06 -- Open Access
Author(s): 
Okyere B, Owusu-Ofori A, Dickerson T, et al.
Reference: 
PLoS ONE 15(7): e0232874

Plasmodium infection among children is a serious public health problem. Asymptomatic malaria infection among humans serves as a significant reservoir for transmitting Plasmodium to uninfected Anopheles mosquitoes, fueling malaria endemicity and asymptomatic malaria may progress to clinical malaria. Therefore, prompt and accurate diagnosis of malaria infection is crucial for the management and control of malaria, especially in endemic areas. This study assessed the point prevalence of asymptomatic malaria infection and evaluated the performance of malaria Rapid Diagnostic Tests (RDT), light microscopy and nested PCR (nPCR) for the diagnosis of asymptomatic malaria infection in a paediatric population in the Atwima Nwabiagya North district, Ghana.

NOT Open Access | Prevalence of Asymptomatic and/or Low-Density Malaria Infection among High-Risk Groups in Peninsular Malaysia

July 7, 2020 - 12:50 -- NOT Open Access
Author(s): 
Noordin NR, Lee PY, Mohd Bukhari FD, Fong MY, Abdul Hamid MH, Jelip J, Mudin RN, Lau YL
Reference: 
Am J Trop Med Hyg. 2020 Jul 6

Asymptomatic and/or low-density malaria infection has been acknowledged as an obstacle to achieving a malaria-free country. This study aimed to determine the prevalence of asymptomatic and/or low-density malaria infection in previously reported malarious localities using nested PCR in four states, namely, Johor, Pahang, Kelantan, and Selangor, between June 2019 and January 2020. Blood samples (n = 585) were collected and were extracted using a QIAamp blood kit.

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