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NOT Open Access | Prevalence of Cardiovascular Complications in Malaria: A Systematic Review and Meta-Analysis

March 17, 2021 - 17:03 -- NOT Open Access
Holm AE, Gomes LC, Farias Marinho CR, Silvestre OM, Vestergaard LS, Biering-Sørensen T, Brainin P
Am J Trop Med Hyg. 2021 Mar 15:tpmd201414

Recent studies have suggested that malaria may affect the cardiovascular system. The aim of this systematic review and meta-analysis was to determine the prevalence of cardiovascular complications in symptomatic malaria patients. We searched databases such as Pubmed, Embase, Cochrane, and Web of Science (January 1950-April 2020) for studies reporting on cardiovascular complications in adults and children with malaria.

NOT Open Access | Prevalence and association of malaria with ABO blood group and hemoglobin level in individuals visiting Mekaneeyesus Primary Hospital, Estie District, northwest Ethiopia: a cross-sectional study

March 4, 2021 - 11:11 -- NOT Open Access
Tazebew B, Munshea A, Nibret E
Parasitol Res. 2021 Mar 3

Malaria is a serious and sometimes fatal mosquito-borne disease caused by protozoan parasite of the genus Plasmodium. ABO blood group antigens represent polymorphic traits inherited among individuals and populations. Differences in blood group antigen expression can increase or decrease host susceptibility to many infections. This study was undertaken to determine the prevalence of malaria and its possible association with ABO blood group and hemoglobin level among individuals attending Mekaneeyesus Primary Hospital, Estie District, northwestern Ethiopia.

Prevalence of malaria and associated factors among under-five children in Sherkole refugee camp, Benishangul-Gumuz region, Ethiopia. A cross-sectional study

February 23, 2021 - 14:03 -- Open Access
Ahmed A, Mulatu K, Elfu B
PLoS One. 2021 Feb 19;16(2):e0246895

Under-five year children are the most vulnerable group affected by malaria, they accounted for 61% of all malaria deaths worldwide. Sherkole refugee camp is stratified under high risk for malaria. Knowledge on malaria prevalence and associated factors among under-five children in Sherkole refugee camp is lacking.

Multi-Indicator and Multistep Assessment of Malaria Transmission Risks in Western Kenya

February 10, 2021 - 09:41 -- Open Access
Zhou G, Zhong D, Lee MC, Wang X, Atieli HE, Githure JI, Githeko AK, Kazura J, Yan G
Am J Trop Med Hyg. 2021 Feb 8:tpmd201211

Malaria risk factor assessment is a critical step in determining cost-effective intervention strategies and operational plans in a regional setting. We develop a multi-indicator multistep approach to model the malaria risks at the population level in western Kenya. We used a combination of cross-sectional seasonal malaria infection prevalence, vector density, and cohort surveillance of malaria incidence at the village level to classify villages into malaria risk groups through unsupervised classification. Generalized boosted multinomial logistics regression analysis was performed to determine village-level risk factors using environmental, biological, socioeconomic, and climatic features.

Molecular characterization of G6PD mutations reveals the high frequency of G6PD Aures in the Lao Theung population

January 13, 2021 - 09:57 -- Open Access
Amkha Sanephonasa, Chalisa Louicharoen Cheepsunthorn, Naly Khaminsou, Onekham Savongsy, Issarang Nuchprayoon and Kamonlak Leecharoenkiat
Malaria Journal 2021 20:30, 7 January 2021

The prevalence and genotypes of G6PD deficiency vary worldwide, with higher prevalence in malaria endemic areas. The first-time assessment of G6PD deficiency prevalence and molecular characterization of G6PD mutations in the Lao Theung population were performed in this study.

Is the source of domestic water associated with the risk of malaria infection? Spatial variability and a mixed-effects multilevel analysis

December 29, 2020 - 15:41 -- Open Access
Shayo FK, Nakamura K, Saber AS, Seino K
Int J Infect Dis. 2020 Dec 23:S1201-9712(20)32585-6

There is a dearth of information about the influence of sources of domestic water and malaria infection in endemic regions such as Tanzania. This study examined geospatial variability and association between the source of domestic water and the malaria prevalence in Tanzania.

NOT Open Access | Diarrhea in Children with Plasmodium falciparum Malaria: A Case-Control Study on the Prevalence and Response to Antimalarial Treatment

December 16, 2020 - 10:10 -- NOT Open Access
Lo Vecchio A, Basile FW, Bruzzese D, Di Dato F, Aol P, Omona V, Smarrazzo A, Guarino A
Am J Trop Med Hyg. 2020 Dec 14

The role of Plasmodium in the etiology of acute diarrhea in developing countries remains controversial, and gastrointestinal (GI) symptoms are inconsistently reported in malaria. In this observational case-control study, we investigated the prevalence and risk factors for GI symptoms in hospitalized malarious children aged 1 month to 5 years in northern Uganda. Children with a diagnosis of Plasmodium falciparum malaria were enrolled as cases, and feverish children in whom malaria was excluded were enrolled as controls.

Increased malaria parasitaemia among adults living with HIV who have discontinued cotrimoxazole prophylaxis in Kitgum district, Uganda

November 12, 2020 - 15:47 -- Open Access
Orishaba P, Kalyango JN, Nankabirwa JI, et al.
PLoS One. 2020 Nov 11;15(11):e0240838

Although WHO recommends cotrimoxazole (CTX) discontinuation among HIV patients who have undergone immune recovery and are living in areas of low prevalence of malaria, some countries including Uganda recommend CTX discontinuation despite having a high malaria burden. We estimated the prevalence and factors associated with malaria parasitaemia among adults living with HIV attending hospital outpatient clinic before and after discontinuation of CTX prophylaxis.

Prevalence and Risk Factors Associated with Malaria among Children Aged Six Months to 14 Years Old in Rwanda: Evidence from 2017 Rwanda Malaria Indicator Survey

November 4, 2020 - 15:13 -- Open Access
Habyarimana F, Ramroop S
Int J Environ Res Public Health. 2020 Oct 30;17(21):E7975

Malaria is a major public health risk in Rwanda where children and pregnant women are most vulnerable. This infectious disease remains the main cause of morbidity and mortality among children in Rwanda. The main objectives of this study were to assess the prevalence of malaria among children aged six months to 14 years old in Rwanda and to identify the factors associated with malaria in this age group.

Malaria in children and women of childbearing age: infection prevalence, knowledge and use of malaria prevention tools in the province of Nyanga, Gabon

November 4, 2020 - 10:00 -- Open Access
Roméo Karl Imboumy-Limoukou, Sydney Maghendji-Nzondo, Jean-Bernard Lekana-Douki, et al.
Malaria Journal 2020 19:387, 2 November 2020

There is little information on the social perception of malaria and the use of preventative measures in Gabon, especially in rural areas. Adequate knowledge of malaria prevention and control can help in reducing the burden of malaria among vulnerable groups, particularly pregnant women and children under 5 years old living in malaria-endemic settings. This study was designed to assess the prevalence of malaria and the knowledge and attitude towards this disease in households in Nyanga Province.


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