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The relationship between facility-based malaria test positivity rate and community-based parasite prevalence

October 8, 2020 - 08:01 -- Open Access
Kamau A, Mtanje G, Mataza C, Malla L, Bejon P, Snow RW
PLoS One. 2020 Oct 7;15(10):e0240058

Malaria surveillance is a key pillar in the control of malaria in Africa. The value of using routinely collected data from health facilities to define malaria risk at community levels remains poorly defined.

NOT Open Access | Asymptomatic Malaria Co-infection of HIV-infected Adults in Nigeria. Prevalence of and Impact on Cognition, Mood and Biomarkers of Systemic Inflammation

October 7, 2020 - 15:43 -- NOT Open Access
Bharti AR, McCutchan JA, Umlauf A, Okwuegbuna OK, Letendre S, Cherner M, Burdo T, Jumare J, Williams K, Blattner W, Royal W
J Acquir Immune Defic Syndr. 2020 Oct 1

HIV and malaria are associated with immunological perturbations and neurocognitive disorders even when asymptomatic. However, the effect of asymptomatic malaria (AM) in HIV-infected adults on neurocognitive impairment (NCI) is not well understood. This study investigated the biomarkers of systemic inflammation and neurocognition in dually-infected Nigerian adults.

Data-driven malaria prevalence prediction in large densely populated urban holoendemic sub-Saharan West Africa

September 30, 2020 - 11:48 -- Open Access
Brown BJ, Manescu P, Fernandez-Reyes D, et al.
Sci Rep. 2020 Sep 28;10(1):15918

Over 200 million malaria cases globally lead to half-million deaths annually. The development of malaria prevalence prediction systems to support malaria care pathways has been hindered by lack of data, a tendency towards universal "monolithic" models (one-size-fits-all-regions) and a focus on long lead time predictions. Current systems do not provide short-term local predictions at an accuracy suitable for deployment in clinical practice.

Potential drug–drug interactions associated with adverse clinical outcomes and abnormal laboratory findings in patients with malaria

September 1, 2020 - 10:32 -- Open Access
Sidra Noor, Mohammad Ismail and Faiza Khadim
Malaria Journal 2020 19:316, 31 August 2020

Hospitalized patients with malaria often present with comorbidities or associated complications for which a variety of drugs are prescribed. Multiple drug therapy often leads to drug–drug interactions (DDIs). Therefore, the current study investigated the prevalence, levels, risk factors, clinical relevance, and monitoring parameters/management guidelines of potential DDIs (pDDIs) among inpatients with malaria.

Prevalence and determinants of malaria infection among children of local farmers in Central Malawi

September 1, 2020 - 09:52 -- Open Access
Emmanuel Chilanga, Delphine Collin-Vézina, Heather MacIntosh, Claudia Mitchell and Katrina Cherney
Malaria Journal 2020 19:308, 27 August 2020

Malaria is a leading cause of morbidity and mortality among children under 5 years in Malawi, and especially among those from rural areas of central Malawi. The goal of this study was to examine the prevalence and determinants of malaria infection among children in rural areas of Dowa district in central Malawi.

A multicenter study of the prevalence and risk factors of malaria and anemia among pregnant women at first antenatal care visit in Ghana

August 25, 2020 - 07:57 -- Open Access
Fondjo LA, Addai-Mensah O, Annani-Akollor ME, Quarshie JT, Boateng AA, Assafuah SE, Owiredu EW
PLoS One. 2020 Aug 21;15(8):e0238077

Malaria in pregnancy remains a major public health problem in Africa and Ghana and has been associated with a variety of pregnancy-related adverse complications. The development of effective and timely health policies for the prevention and control of malaria and anemia in pregnancy; requires current and consistent data on the prevalence and risk factors. We report the prevalence and risk factors of malaria and anemia from three major hospitals across three regions in Ghana.

Risk factors for malaria infection prevalence and household vector density between mass distribution campaigns of long-lasting insecticidal nets in North-western Tanzania

August 24, 2020 - 14:07 -- Open Access
Jacklin F. Mosha, Eliud Lukole, Natacha Protopopoff, et al.
Malaria Journal 2020 19:297, 20 August 2020

Long-lasting insecticidal nets (LLINs) are the most widely deployed vector control intervention in sub-Saharan Africa to prevent malaria. Recent reports indicate selection of pyrethroid insecticide resistance is widespread in mosquito vectors. This paper explores risk factors associated with malaria infection prevalence and vector density between mass distribution campaigns, changes in net coverage, and loss of protection in an area of high pyrethroid resistance in Northwest Tanzania.

Performance of IRS on malaria prevalence and incidence using pirimiphos-methyl in the context of pyrethroid resistance in Koulikoro region, Mali

August 17, 2020 - 13:22 -- Open Access
Fousseyni Kané, Moussa Keïta, Boïssé Traoré, Sory Ibrahim Diawara, Sidy Bane, Souleymane Diarra, Nafomon Sogoba and Seydou Doumbia
Malaria Journal 2020 19:286, 12 August 2020

Koulikoro Health District is one of three districts of Mali where the indoor residual spray (IRS) has been implemented from 2008 to 2016. With widespread of resistance to pyrethroid, IRS was shifted from pyrethroid to pirimiphos-methyl from 2014 to 2016. The objective of this study was to assess the added value of IRS to LLINs on the prevalence of parasitaemia and malaria incidence among children under 10 years old.

Prevalence and associated factors of malaria among pregnant women in Sherkole district, Benishangul Gumuz regional state, West Ethiopia

August 10, 2020 - 14:38 -- Open Access
Gontie GB, Wolde HF, Baraki AG
BMC Infect Dis. 2020 Aug 5;20(1):573

Malaria during pregnancy leads to serious adverse effects on mothers and the fetus. Approximately 25 million pregnant women in sub-Saharan Africa live at risk of malaria. This study would help to achieve Sustainable Development Goals (SDGs) by improving programs that deal with the prevention of malaria. Therefore, this study aimed to assess the prevalence and associated factors of malaria among pregnant women.

Global prevalence and mortality of severe Plasmodium malariae infection: a systematic review and meta-analysis

August 4, 2020 - 15:51 -- Open Access
Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni D. Milanez and Frederick R. Masangkay
Malaria Journal 2020 19:274, 31 July 2020

Severe complications among patients with Plasmodium malariae infection are rare. This is the first systematic review and meta-analysis demonstrating the global prevalence and mortality of severe P. malariae infection in humans.


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