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Africa

Free Book for MalariaWorld Members!

November 27, 2012 - 21:45 -- Bart G.J. Knols

This week I was contacted by Dr. Dana Dalrymple with a very unusual offer. He wishes to provide all MalariaWorld subscribers free access to his book 'Artemisia annua, Artemisinin, ACTs & Malaria Control in Africa' published just seven months ago. This is truly remarkable and we highly appreciate this gesture!

In his email he said: "This will get it to the heart of the international malaria community and doubtless reach many who otherwise may not have heard of, or had access to, it." That is the spirit of truly open and global collaboration we aim to achieve with MalariaWorld. So a big 'Thank you' to Dr. Dalrymple! If you download it, why not send him a private message through the platform (available to subcribers) to let him know you appreciate his action...

WHO's interim position statement on larviciding for malaria control in Africa

April 30, 2012 - 16:05 -- Bart G.J. Knols

Last week, WHO published a statement regarding the potential of larviciding for malaria control in Africa. This followed the circulation of a draft version of the statement in August 2011. That draft was sent to a limited group of people (how many I don't know) for comments (including myself). I attach the official version to this editorial.

Guest Editorial: Don't fake it!

January 26, 2012 - 13:22 -- Bart G.J. Knols

This guest editorial was written by Dr. Lotte Van Dijk in The Netherlands.

 

Many of you will have come across counterfeit or substandard drugs in your careers and I’m sure many of you will understand my frustration. Therefore, I was really happy to see that the study on poor-quality anti-malarials by Dr Paul Newton and his team got the attention of the media. Even though their study was not large-scale and even though it cannot provide an accurate estimation of the prevalence of the fake anti-malarials all over Africa, it does provide an insight into the seriousness of the problem: it is severe!

Malaria can be eliminated from Africa

October 6, 2011 - 09:30 -- Bart G.J. Knols

A perspective article carrying the above title appeared in the American Journal of Tropical Medicine and Hygiene this month. As it was freely accessible I have taken the liberty to attach it to this editorial (hoping the publisher will not come after me...) for those of you that have not seen it. 

In it, Carlos Campbell and Rick Steketee inject encouragement into all of us that we have made substantial gains in the battle against malaria over the last decade, and that with the same relentlessness we may actually succeed in wiping the scourge off the continent. The article is a pleasant read when one starts up the computer and reads this first thing in the morning...

Climate & malaria

March 22, 2010 - 13:51 -- Sander Koenraadt

These days, not only scientists are debating about the existence and potential impact of climate change. Since the mishaps in the fourth assessment report of the IPCC were revealed and received enormous media exposure, even my parents in law (non-scientists) have been asking me about it. Now I wonder when my 3-year old daughter will start casting doubts…

Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting

October 25, 2009 - 13:48 -- Bart G.J. Knols
Tags: 
Author(s): 
Noranate N et al.
Reference: 
BMC Microbiology 2009, 9:219 (15 October 2009)

The Pfmsp1 block2 locus presents a very large population sequence diversity. The lack of stable acquisition of novel antibody specificities despite exposure to novel allelic forms is reminiscent of clonal imprinting. The locus appears under antibody-mediated diversifying selection in a variable environment that maintains a balance between the various family types without selecting for sequence variant allelic forms. There is no evidence of positive selection for intra-family sequence diversity, consistent with the observed characteristics of the antibody response.

 

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