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Malaria serology data from the Guiana shield: first insight in IgG antibody responses to Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae antigens in Suriname

October 8, 2020 - 15:21 -- Open Access
Mergiory Y. Labadie-Bracho, Farah T. van Genderen and Malti R. Adhin
Malaria Journal 2020 19:360, 8 October 2020

Suriname has accomplished a steep decline in malaria burden, even reaching elimination levels. Plasmodium serology data are not available for Suriname and even extremely scarce within the region, therefore malaria serology testing was introduced, country customized cut-off values were determined and a study was performed to explore the antibody status for Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae.

Researchers’ perceptions of malaria eradication: findings from a mixed-methods analysis of a large online survey

October 8, 2020 - 15:19 -- Open Access
Joe Brew, Menno Pradhan, Jacqueline Broerse and Quique Bassat
Malaria Journal 2020 19:359, 8 October 2020

The value of malaria eradication, the permanent reduction to zero of the worldwide incidence of malaria infection caused by human malaria parasites, would be enormous. However, the expected value of an investment in an intended, but uncertain, outcome hinges on the probability of, and time until, its fulfilment. Though the long-term benefits of global malaria eradication promise to be large, the upfront costs and uncertainty regarding feasibility and timeframe make it difficult for policymakers and researchers to forecast the return on investment.

Uncomplicated falciparum malaria among schoolchildren in Bajil district of Hodeidah governorate, west of Yemen: association with anaemia and underweight

October 8, 2020 - 08:12 -- Open Access
Talal S. Alwajeeh, Rashad Abdul-Ghani, Amal F. Allam, Hoda F. Farag, Safia S. M. Khalil, Amel Y. Shehab, Mona H. El-Sayad, Raed A. Alharbi, Shaia S. R. Almalki and Ahmed A. Azazy
Malaria Journal 2020 19:358, 7 October 2020

Malaria, malnutrition and anaemia are major public health problems in Yemen, with Hodeidah being the most malaria-afflicted governorate. To address the lack of relevant studies, this study was conducted to determine the prevalence of Plasmodium falciparum and its relation to nutritional status and haematological indices among schoolchildren in Bajil district of Hodeidah governorate, west of Yemen.

Lure, retain, and catch malaria mosquitoes. How heat and humidity improve odour-baited trap performance

October 8, 2020 - 08:10 -- Open Access
Antoine Cribellier, Jeroen Spitzen, Henry Fairbairn, Cedric van de Geer, Johan L. van Leeuwen and Florian T. Muijres
Malaria Journal 2020 19:357, 7 October 2020

When seeking a human for a blood meal, mosquitoes use several cues to detect and find their hosts. From this knowledge, counter-flow odour-baited traps have been developed that use a combination of CO2, human-mimicking odour, visual cues and circulating airflow to attract and capture mosquitoes. Initially developed for monitoring, these traps are now also being considered as promising vector control tools. The traps are attractive to host-seeking mosquitoes, but their capture efficiency is low. It has been hypothesized that the lack of short-range host cues, such as heat and increased local humidity, often prevent mosquitoes from getting close enough to get caught; this lack might even trigger avoidance manoeuvres near the capture region.

History of malaria control in Rwanda: implications for future elimination in Rwanda and other malaria-endemic countries

October 8, 2020 - 08:08 -- Open Access
Corine Karema, Shawn Wen, Abigail Sidibe, Jennifer L. Smith, Roly Gosling, Emmanuel Hakizimana, Marcel Tanner, Abdisalan M. Noor and Allison Tatarsky
Malaria Journal 2020 19:356, 7 October 2020

Malaria was first reported in Rwanda in the early 1900s with significant heterogeneity and volatility in transmission over subsequent decades. Here, a comprehensive literature review of malaria transmission patterns and control strategies in Rwanda between 1900 and 2018 is presented to provide insight into successes and challenges in the country and to inform the future of malaria control in Rwanda.

Plasmodium vivax malaria across South America: management guidelines and their quality assessment

October 8, 2020 - 08:02 -- Open Access
Rodríguez JAI, Rodríguez SNI, Olivera MJ
Rev Soc Bras Med Trop. 2020 Oct 5;53:e20200179

Plasmodium vivax malaria represents a major public health problem. This study presents the quality assessment of clinical practice guidelines for the management of P. vivax malaria.

The relationship between facility-based malaria test positivity rate and community-based parasite prevalence

October 8, 2020 - 08:01 -- Open Access
Kamau A, Mtanje G, Mataza C, Malla L, Bejon P, Snow RW
PLoS One. 2020 Oct 7;15(10):e0240058

Malaria surveillance is a key pillar in the control of malaria in Africa. The value of using routinely collected data from health facilities to define malaria risk at community levels remains poorly defined.

Importance of kelch 13 C580Y mutation in the studies of artemisinin resistance in Plasmodium falciparum in Greater Mekong Subregion

October 7, 2020 - 16:23 -- Open Access
Zaw MT, Lin Z, Emran NA
J Microbiol Immunol Infect. 2020 Oct;53(5):676-681

The mortality caused by Plasmodium falciparum was reduced by Artemisinin (ART) and ART combination therapy (ACT). However, Artemisinin resistance (ART-R) emerge during 2008 in Cambodia and spread to Greater Mekong Subregion (GMS).

Not Open Access | Flagging performance of Sysmex XN-10 haematology analyser for malaria detection

October 7, 2020 - 16:20 -- NOT Open Access
Dumas C, Tirard-Collet P, Mestrallet F, Girard S, Jallades L, Picot S, Bienvenu AL.
J Clin Pathol. 2020 Oct;73(10):676-677

The aim was to assess the flagging performance of Sysmex XN-10 haematology analyser for malaria detection through the parasitic red blood cell ('pRBC') alarm.

NOT Open Access | Sequential classification system for recognition of malaria infection using peripheral blood cell images

October 7, 2020 - 16:17 -- NOT Open Access
Molina A, Alférez S, Boldú L, Acevedo A, Rodellar J, Merino A
J Clin Pathol. 2020 Oct;73(10):665-670

Morphological recognition of red blood cells infected with malaria parasites is an important task in the laboratory practice. Nowadays, there is a lack of specific automated systems able to differentiate malaria with respect to other red blood cell inclusions. This study aims to develop a machine learning approach able to discriminate parasitised erythrocytes not only from normal, but also from other erythrocyte inclusions, such as Howell-Jolly and Pappenheimer bodies, basophilic stippling as well as platelets overlying red blood cells.


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