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Not Open Access | Antimalarial chemoprophylaxis and the risk of neuropsychiatric disorders

April 24, 2013 - 16:30 -- NOT Open Access
Author(s): 
Cornelia Schneider, Miriam Adamcova, Susan S. Jick, Patricia Schlagenhauf, Mary K. Miller, Hans-Georg Rhein, Christoph R. Meier
Reference: 
Travel Medicine and Infectious Disease, Volume 11, Issue 2, March–April 2013, Pages 71-80
MalariaWorld

We used the General Practice Research Database to conduct a follow-up study with a nested case–control analysis.

Use of Bacillus thuringiensis var israelensis as a viable option in an Integrated Malaria Vector Control Programme in the Kumasi Metropolis, Ghana

April 24, 2013 - 16:16 -- Open Access
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Author(s): 
Nartey R, Owusu-Dabo E, Kruppa T, Baffour-Awuah S, Annan A, Oppong S, Becker N, Obiri-Danso K
Reference: 
Parasites & Vectors 2013, 6:116 (22 April 2013)
MalariaWorld

This study reveals that Bti at a very low dosage of 0.2 kg/ha is highly effective against Anopheles larvae and therefore offers viable options for the management of vector mosquitoes.

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Molecular and epidemiological characterization of Plasmodium vivax recurrent infections in southern Mexico

April 23, 2013 - 16:21 -- Open Access
Author(s): 
Gonzalez-Ceron L, Mu J, Santillán F, Joy D, Sandoval MA, Camas G, Su X, Choy EV, Torreblanca R
Reference: 
Parasites & Vectors 2013, 6:109 (18 April 2013)
MalariaWorld

 

Symptomatic patients with more than one P. vivax infection were followed up, and blood samples were collected from primary and recurrent infections. DNA extracted from infected blood samples was analyzed for restriction fragment length polymorphism (RFLP) in genes encoding csp and msp3alpha, as well as size variation in seven microsatellites.

Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

April 23, 2013 - 07:16 -- Open Access
Author(s): 
McCoy ME, Golden HE, Doll TA, Yang Y, Kaba SA, Burkhard P, Lanar DE
Reference: 
Malaria Journal 2013, 12:136 (22 April 2013)
MalariaWorld

This paper describes the examination of humoral and cellular immune mechanisms induced by PfCSP-SAPN vaccination which result in sterile host protection against a transgenic P. berghei malaria sporozoite expressing the P. falciparum CSP, and which significantly inhibits native P. falciparum sporozoites from invading and developing within cultured human hepatocytes.

Artemisinin-based combination therapy availability and use in the private sector of five AMFm phase 1 countries

April 23, 2013 - 07:15 -- Open Access
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Author(s): 
Davis B, Ladner J, Sams K, Tekinturhan E, de Korte D, Saba J
Reference: 
Malaria Journal 2013, 12:135 (22 April 2013)
MalariaWorld

Results from this study indicate that the AMFm has not fully achieved its affordability and crowd-out objectives

Temporal evaluation of commitment to sexual development in Plasmodium falciparum

April 23, 2013 - 07:11 -- Open Access
Author(s): 
Peatey CL, Dixon MW, Gardiner DL, Trenholme KR
Reference: 
Malaria Journal 2013, 12:134 (22 April 2013)
MalariaWorld

The observation that cholera toxin treatment did not affect cAMP levels indicates that while addition of cholera toxin does increase gametocytogenesis the method by which it induces increased commitment is not immediately obvious, except that is unlikely to be via heterotrimeric G proteins.

A multi-locus approach to barcoding in the Anopheles strodei subgroup (Diptera: Culicidae)

April 23, 2013 - 06:54 -- Open Access
Author(s): 
Bourke BP, Oliveira TM, Suesdek L, Bergo ES, Sallum MA
Reference: 
Parasites & Vectors 2013, 6:111 (19 April 2013)
MalariaWorld

Our study corroborates the existence of An. albertoi, An. CP Form and An. strodei in the An. strodei subgroup and identifies four species under An. arthuri informally named A-D herein. 

Population-Based Laboratory Surveillance of Imported Malaria in Metropolitan Calgary, 2000–2011

April 22, 2013 - 12:58 -- Open Access
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Author(s): 
Clara S. Lee, Daniel B. Gregson, Deirdre Church, Kevin B. Laupland, Rose Eckhardt, Terry Ross, Wilson Chan, Dylan R. Pillai
Reference: 
PLoS ONE 8(4): e60751
MalariaWorld

Increased travel leads to a heightened risk of imported infectious diseases.

Quantitative Bioluminescent Imaging of Pre-Erythrocytic Malaria Parasite Infection Using Luciferase-Expressing Plasmodium yoelii

April 22, 2013 - 12:34 -- Open Access
Author(s): 
Jessica L. Miller, Sara Murray, Ashley M. Vaughan, Anke Harupa, Brandon Sack, Michael Baldwin, Ian N. Crispe, Stefan H. I. Kappe
Reference: 
PLoS ONE 8(4): e60820.
MalariaWorld

The liver stages of Plasmodium parasites are important targets for the development of anti-malarial vaccine candidates and chemoprophylaxis approaches that aim to prevent clinical infection.

Early parasitological response following artemisinin-containing regimens: a critical review of the literature

April 22, 2013 - 12:29 -- Open Access
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Author(s): 
Das D, Price RN, Bethell D, Guerin PJ, Stepniewska K
Reference: 
Malaria Journal 2013, 12:125 (19 April 2013)
MalariaWorld

These results highlight the normal distribution of early parasitological responses following ACT, and the influence that heterogeneity in study design, host and parasite factors have in confounding a surveillance system based on Day 3 parasite positivity.

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