The world's scientific and social network for malaria professionals
9377 malaria professionals are enjoying the free benefits of MalariaWorld today

malaria

Informing new or improved vector control tools for reducing the malaria burden in Tanzania: a qualitative exploration of perceptions of mosquitoes and methods for their control among the residents of Dar es Salaam

October 12, 2017 - 15:32 -- Open Access
Tags: 
Author(s): 
Christina Makungu, Stephania Stephen, Salome Kumburu, Nicodem J. Govella, Stefan Dongus, Zoe Jane-Lara Hildon, Gerry F. Killeen and Caroline Jones
Reference: 
Malaria Journal 2017 16:410, 11 October 2017

Outdoor transmission is widely accepted as an obstacle to malaria elimination.

Country: 

Modelling dynamic change of malaria transmission in holoendemic setting (Dielmo, Senegal) using longitudinal measures of antibody prevalence to Plasmodium falciparum crude schizonts extract

October 12, 2017 - 15:30 -- Open Access
Author(s): 
Oumy Niass, Philippe Saint-Pierre, Aïssatou Toure Balde, et al.
Reference: 
Malaria Journal 2017 16:409, 11 October 2017

The results of the study suggested that crude extract was a good serological tool that could be used to assess the level of malaria exposure in areas where malaria transmission is declining.

NOT Open Access | Synthesis, characterization, and cellular localization of a fluorescent probe of the antimalarial 8-aminoquinoline primaquine

October 12, 2017 - 15:26 -- NOT Open Access
Author(s): 
Adonis McQueen, Lynn D. Blake, Dennis E. Kyle, et al.
Reference: 
Bioorganic & Medicinal Chemistry Letters, Volume 27, Issue 20, 15 October 2017, Pages 4597-4600

Primaquine (PQ) is the only commercially available drug that clears dormant liver stages of malaria and blocks transmission to mosquito vectors.

Medical Treatment: 

The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito

October 12, 2017 - 15:19 -- Open Access
Tags: 
Author(s): 
Andrew M. Hammond, Kyros Kyrou, Tony Nolan, et al.
Reference: 
PLoS Genet 13(10): e1007039

Gene drives have enormous potential for the control of insect populations of medical and agricultural relevance.

NOT Open Access | Mother-Newborn Pairs in Malawi Have Similar Antibody Repertoires to Diverse Malaria Antigens

October 12, 2017 - 15:18 -- NOT Open Access
Author(s): 
Sarah Boudová, Jenny A. Walldorf, Miriam K. Laufer, et al.
Reference: 
Clin Vaccine Immunol October 2017 vol. 24 no. 10 e00136-17

Maternal antibodies may play a role in protecting newborns against malaria disease.

Not Open Access | Near-atomic structure of jasplakinolide-stabilized malaria parasite F-actin reveals the structural basis of filament instability

October 12, 2017 - 15:17 -- NOT Open Access
Author(s): 
Sabrina Pospich, Esa-Pekka Kumpula, Julian von der Ecken, Juha Vahokoski, Inari Kursula, and Stefan Raunser
Reference: 
PNAS October 3, 2017 vol. 114 no. 40 10636-10641

During their life cycle, apicomplexan parasites, such as the malaria parasite Plasmodium falciparum, use actomyosin-driven gliding motility to move and invade host cells.

Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana

October 12, 2017 - 15:16 -- Open Access
Author(s): 
Kwadwo A. Kusi, Emmanuel A. Manu, Kwadwo A. Koram, et al.
Reference: 
PLoS ONE 12(9): e0185303

The data contribute to understanding the underlying mechanism of the acquisition of strain-transcending antibody immunity following repeated exposure to diverse parasite strains.

NOT Open Access | Optimal antimalarial dose regimens for chloroquine in pregnancy based on population pharmacokinetic modelling

October 12, 2017 - 15:14 -- NOT Open Access
Tags: 
Author(s): 
Sam Salman, Francesca Baiwog, Timothy M.E. Davis, et al.
Reference: 
International Journal of Antimicrobial Agents, Volume 50, Issue 4, October 2017, Pages 542-551

Despite extensive use and accumulated evidence of safety, there have been few pharmacokinetic studies from which appropriate chloroquine (CQ) dosing regimens could be developed specifically for pregnant women.

Medical Treatment: 

Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells

October 12, 2017 - 15:12 -- Open Access
Tags: 
Author(s): 
Nyamekye Obeng-Adjei, Silvia Portugal, Peter D. Crompton, et al.
Reference: 
PLoS Pathog 13(9): e1006576

Many chronic infections, including malaria and HIV, are associated with a large expansion of CD21−CD27− ‘atypical’ memory B cells (MBCs) that exhibit reduced B cell receptor (BCR) signaling and effector functions.

Can the collection of expired long-lasting insecticidal nets reduce their coverage and use? Sociocultural aspects related to LLIN life cycle management and use in four districts in Madagascar

October 11, 2017 - 14:15 -- Open Access
Tags: 
Author(s): 
Ambinina Ramanantsoa, Marta Wilson-Barthes, Koen Peeters Grietens, et al.
Reference: 
Malaria Journal 2017 16:404, 10 October 2017

The collection of LLINs for recycling/disposal can lead to lower coverage under certain conditions.

Country: 

Pages

Subscribe to RSS - malaria