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Age and geographic patterns of Plasmodium falciparum malaria infection in a representative sample of children living in Burkitt lymphoma-endemic areas of northern Uganda

March 22, 2017 - 15:23 -- Open Access
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Author(s): 
Marlena Maziarz, Tobias Kinyera, Sam M. Mbulaiteye, et al.
Reference: 
Malaria Journal 2017 16:124, 20 March 2017

The study observed high but geographically and demographically heterogenous patterns of asymptomatic malaria prevalence among children living in northern Uganda.

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Clinical and molecular surveillance of drug resistant vivax malaria in Myanmar (2009–2016)

March 22, 2017 - 14:55 -- Open Access
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Author(s): 
Myat Htut Nyunt, Jin-Hee Han, Bo Wang, Khin Myo Aye, Kyin Hla Aye, Seong-Kyun Lee, Ye Htut, Myat Phone Kyaw, Kay Thwe Han and Eun-Taek Han
Reference: 
Malaria Journal 2017 16:117, 16 March 2017

Although clinical failure rate was low, widespread distribution of chloroquine and antifolate resistance molecular makers alert to the emergence and spread of drug resistance vivax malaria in Myanmar.

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NOT Open Access | Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

March 16, 2017 - 16:22 -- NOT Open Access
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Author(s): 
Benjamin Mordmüller, Güzin Surat, Peter G. Kremsner, et al.
Reference: 
Nature 542, 445–449 (23 February 2017)

A highly protective malaria vaccine would greatly facilitate the prevention and elimination of malaria and containment of drug-resistant parasites1.

Housing Improvements and Malaria Risk in Sub-Saharan Africa: A Multi-Country Analysis of Survey Data

March 16, 2017 - 16:21 -- Open Access
Author(s): 
Lucy S. Tusting, Christian Bottomley, Harry Gibson, Immo Kleinschmidt, Andrew J. Tatem, Steve W. Lindsay, Peter W. Gething
Reference: 
PLoS Med 14(2): e1002234

Housing quality is an important risk factor for malaria infection across the spectrum of malaria endemicity in SSA, with a strength of association between housing quality and malaria similar to that observed between ITN use and malaria.

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Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes

March 15, 2017 - 16:28 -- Open Access
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Author(s): 
Timothy W. Phares, Anthony D. May, Christopher J. Genito, Nathan A. Hoyt, Farhat A. Khan, Michael D. Porter, Margot DeBot, Norman C. Waters, Philippe Saudan and Sheetij Dutta
Reference: 
Malaria Journal 2017 16:115, 13 March 2017

Despite some immunologic parallels between models, these data demonstrate that differences between the immune responses induced in the two models risk conflicting decisions regarding potential vaccine utility in humans.

Combining indoor and outdoor methods for controlling malaria vectors: an ecological model of endectocide-treated livestock and insecticidal bed nets

March 15, 2017 - 16:00 -- Open Access
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Author(s): 
Laith Yakob, Mary Cameron and Jo Lines
Reference: 
Malaria Journal 2017 16:114, 13 March 2017

Targeting blood-feeding mosquitoes by treating livestock with endectocides offers a potentially useful complement to existing malaria control programmes centred on LLIN distribution.

Burden of malaria in mobile populations in the Greater Accra region, Ghana: a cross- sectional study

March 14, 2017 - 13:08 -- Open Access
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Author(s): 
Nouhoum Diallo, Patricia Akweongo, Ernest Maya, Moses Aikins and Bismark Sarfo
Reference: 
Malaria Journal 2017 16:109, 9 March 2017

This study demonstrated that the prevalence of malaria is high among hawkers and long distance truck drivers.

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Prevalence and determinants of malaria among children in Zambézia Province, Mozambique

March 14, 2017 - 13:07 -- Open Access
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Author(s): 
James G. Carlucci, Meridith Blevins Peratikos, Charlotte B. Cherry, Melanie L. Lopez, Ann F. Green, Lazaro González-Calvo and Troy D. Moon
Reference: 
Malaria Journal 2017 16:108, 9 March 2017

Self-reported symptomatic malaria is highly prevalent among children in Zambézia Province, Mozambique and varies significantly between diverse districts.

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A systematic review on malaria sero-epidemiology studies in the Brazilian Amazon: insights into immunological markers for exposure and protection

March 14, 2017 - 13:02 -- Open Access
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Author(s): 
Pedro M. Folegatti, André M. Siqueira, Wuelton M. Monteiro, Marcus Vinícius G. Lacerda, Chris J. Drakeley and Érika M. Braga
Reference: 
Malaria Journal 2017 16:107, 7 March 2017

This systematic review identifies potential biomarkers of P. falciparum and P. vivax exposure in areas with variable and unstable malaria transmission in Brazil.

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Rapid diagnostic tests failing to detect Plasmodium falciparum infections in Eritrea: an investigation of reported false negative RDT results

March 14, 2017 - 13:01 -- Open Access
Author(s): 
Araia Berhane, Mulugeta Russom, Iyassu Bahta, Filmon Hagos, Michael Ghirmai and Selam Uqubay
Reference: 
Malaria Journal 2017 16:105, 6 March 2017

The investigation confirmed high false-negativity rate in PfHRP-2 detecting RDTs and has ruled out quality of RDTs, storage, handling and operator error as causes of the reported problem.

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