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NOT Open Access | Malaria fighters' latest chemical weapon may not last long

September 8, 2020 - 11:56 -- NOT Open Access
Makoni M
Science. 2020 Sep 4;369(6508):1153

Two years ago, the World Health Organization (WHO) gave the green light for clothianidin, long used to kill crop pests, to be added to the current mainstays of indoor mosquito control, which are losing their effectiveness as the insects develop resistance.

Antibodies to full-length and the DBL5 domain of VAR2CSA in pregnant women after long-term implementation of intermittent preventive treatment in Etoudi, Cameroon

August 18, 2020 - 14:55 -- Open Access
Djontu JC, Lloyd YM, Megnekou R, Seumko'o RMN, Salanti A, Taylor DW, Leke RGF
PLoS ONE 15(8): e0237671

In high malaria transmission settings, the use of sulfadoxine-pyrimethamine-based intermittent preventive treatment during pregnancy (IPTp-SP) has resulted in decreased antibody (Ab) levels to VAR2CSA. However, information of Ab levels in areas of low or intermediate malaria transmission after long-term implementation of IPTp-SP is still lacking. The present study sought to evaluate antibody prevalence and levels in women at delivery in Etoudi, a peri-urban area in the capital of Yaoundé, Cameroon, that is a relatively low-malaria transmission area.

NOT Open Access | Malaria in the third trimester and maternal-perinatal outcome

June 9, 2020 - 11:41 -- NOT Open Access
Nkwabong E, Mayane DN, Meka E, Essiben F
Int J Gynaecol Obstet. 2020 Jun 8

To evaluate maternal and perinatal outcomes in cases of third-trimester malaria (TTM).

The effect of improved housing on indoor mosquito density and exposure to malaria in the rural community of Minkoameyos, Centre Region of Cameroon

May 6, 2020 - 15:06 -- Open Access
Rachel L. Nguela, Jude D. Bigoga, Rose G. F. Leke, et al.
Malaria Journal 2020 19:172, 3 May 2020

This study evaluated the effectiveness of improved housing on indoor residual mosquito density and exposure to infected Anophelines in Minkoameyos, a rural community in southern forested Cameroon.

Severe malaria in Cameroon: Pattern of disease in children at the Yaounde Gynaeco-Obstetric and Pediatric hospital

May 5, 2020 - 13:11 -- Open Access
Chiabi A, Djimafo ANM, Nguefack S, Mah E, Nguefack Dongmo F, Angwafo F
J Infect Public Health. 2020 Apr 29. pii: S1876-0341(20)30393-2

Malaria is the most widely spread parasitic disease in the world, especially in the tropics affecting mostly children and pregnant women. In children, mostly under-fives carry the heaviest burden in terms of morbidity and mortality. The aim of this study was to determine the epidemiological and clinical aspects, and outcome of children 3 months to 15 years old with severe malaria at the Yaounde Gynaeco-Obstetric and Pediatric Hospital (YGOPH), a referral hospital in Yaounde, Cameroon.

Influence of malaria, soil-transmitted helminths and malnutrition on haemoglobin level among school-aged children in Muyuka, Southwest Cameroon: A cross-sectional study on outcomes

April 6, 2020 - 08:02 -- Open Access
Sumbele IUN, Nkain AJ, Ning TR, Anchang-Kimbi JK, Kimbi HK
PLoS One. 2020 Mar 30;15(3):e0230882

The health of school-aged children (SAC) is often compromised by malaria parasitaemia (MP), soil-transmitted helminths (STH), and malnutrition in the tropics. The aim of this study was to determine the prevalence and influence of MP, STH and malnutrition on haemoglobin (Hb) levels as well as identify its predictors.

Genetic diversity of Plasmodium falciparum and genetic profile in children affected by uncomplicated malaria in Cameroon

March 23, 2020 - 11:35 -- Open Access
Theresia Njuabe Metoh, Jun-Hu Chen, Philip Fon-Gah, Xia Zhou, Roger Moyou-Somo and Xiao-Nong Zhou
Malaria Journal 2020 19:115, 8 March 2020

Malaria is a major public health problem in Cameroon. The study of the genetic diversity within parasite population is essential for understanding the mechanism underlying malaria pathology and to determine parasite clones profile in an infection, for proper malaria control strategies. The objective of this study was to perform a molecular characterization of highly polymorphic genetic markers of Plasmodium falciparum, and to determine allelic distribution with their influencing factors valuable to investigate malaria transmission dynamics in Cameroon.

Coverage and effectiveness of intermittent preventive treatment in pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) on adverse pregnancy outcomes in the Mount Cameroon area, South West Cameroon

March 9, 2020 - 13:51 -- Open Access
Judith K. Anchang-Kimbi, Laken N. Kalaji, Harry F. Mbacham, Godlove B. Wepnje, Tobias O. Apinjoh, Irene U. Ngole Sumbele, Jodie Dionne-Odom, Alan T. N. Tita and Eric A. Achidi
Malaria Journal 2020 19:100, 2 March 2020

Growing concerns about the waning efficacy of IPTp-SP warrants continuous monitoring and evaluation. This study determined coverage of IPTp-SP and compared the effectiveness of the 3-dose to 2-dose regimen on placental malaria (PM) infection and low birth weight (LBW) in the Mount Cameroon area.

Implication of Anopheles funestus in malaria transmission in the city of Yaoundé, Cameroon

February 22, 2020 - 16:52 -- Open Access
Djamouko-Djonkam L, Nkahe DL, Kopya E, Talipouo A, Ngadjeu CS, Doumbe-Belisse P, Bamou R, Awono-Ambene P, Tchuinkam T, Wondji CS, Antonio-Nkondjio C
Parasite, Volume 27, 2020

The contribution of Anopheles funestus to malaria transmission in the urban environment is still not well documented. The present study assesses the implication of An. funestus in malaria transmission in two districts, Nsam and Mendong, in the city of Yaoundé. Adult mosquitoes were collected using Centers for Disease Control and Prevention miniature light traps (CDC-LT) and human landing catches from April 2017 to March 2018 and were identified morphologically to the species level. Those belonging to the Anopheles gambiae complex and to the Anopheles funestus group were further processed by PCR to identify members of each complex/group.

Influence of house characteristics on mosquito distribution and malaria transmission in the city of Yaoundé, Cameroon

February 3, 2020 - 17:24 -- Open Access
Carmene S. Ngadjeu, Patricia Doumbe-Belisse, Abdou Talipouo, Landre Djamouko-Djonkam, Parfait Awono-Ambene, Sevilor Kekeunou, Wilson Toussile, Charles S. Wondji and Christophe Antonio-Nkondjio
Malaria Journal 2020 19:53, 30 January 2020

Improving house structure is known to limit contact between humans and mosquitoes and reduce malaria transmission risk. In the present study, the influence of house characteristics on mosquito distribution and malaria transmission risk was assessed in the city of Yaoundé.


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