In a recent article about the spread of resistance to ACT in SE Asia, the authors recommend new drugs and better drug strategies:
'FEMS Microbiol Rev. 2016 Sep 8. pii: fuw037. [Epub ahead of print]
The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.
Woodrow CJ1, White NJ2'.
Similarly, multiple resistance of Anopheline vectors is supposedly to be met with more careful selection of insecticides!