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Malaria Minute Podcast: Cyclone Idai Causes ‘Spike’ in Malaria Cases

March 29, 2019 - 07:14 -- Malaria World

Cyclone Idai Causes ‘Spike’ in Malaria Cases
By Thomas Locke
Cyclone Idai causes ‘spike’ in malaria cases, Oxford Uni researchers head to Africa to sequence mosquito DNA and the NothingButNets Leader Summit takes place in the US capitol.
Listen to this podcast

 

New edition of the MESA Correspondents Programme

March 19, 2019 - 09:14 -- MESA Alliance

The University of Malaya hosted the "Current Tools to Combat Malaria - with Special Focus on Plasmodium knowlesi" workshop on March 4 - 8, 2019, which had 20 participants from eight different countries. Dr Lucas Low Van Lun covered this intensive week of lectures and practical sessions and reported the daily lessons learnt in a series of reports posted in the Resource Hub.

WHO guidelines for malaria vector control

March 7, 2019 - 13:35 -- Malaria World

The Guidelines for malaria vector control provide a “one-stop shop” for all countries and partners working to implement effective malaria vector control measures. They cover the 2 core malaria vector control interventions – ITNs and IRS – as well as supplementary interventions, namely chemical and biological larvicides, and personal protection measures, such as the use of topical repellents.

Book: History of the successful struggle against malaria in the Islamic Republic of Iran

February 28, 2019 - 17:17 -- Malaria World

This report has been prepared to provide a comprehensive account of the history of malaria and its control in the Islamic Republic of Iran for specialists and lay readers alike. It is based on published and unpublished reports, especially from the Ministry of Health and Medical Education, Tehran, and from the World Health Organization. The main findings are summarized below.

Malaria: Writing Precisely

February 9, 2019 - 00:08 -- Miles Markus

 

Attention is drawn to the following three publications that are relevant to the preparation of manuscripts on malaria:

 

Markus, M.B. 2019. Plasmodium – Yet More Don’ts. Trends in Parasitology 35 (2): 101–102.

https://doi.org/10.1016/j.pt.2018.11.006

McFadden, G.I. 2019. Plasmodium – More Don’ts. Trends in Parasitology 35 (1): 4–6.

https://doi.org/10.1016/j.pt.2018.10.002

Why does vivax malaria recur?

January 24, 2019 - 23:14 -- Miles Markus

An article on vivax malarial recurrences was highlighted in the "Global Malaria News" section of last week's MalariaWorld Newsletter. Below (in the next paragraph) is a relevant explanation concerning the article (http://theconversation.com/why-does-malaria-recur-how-pieces-of-the-puzz...):

New from MESA: Open consultation on WHO prioritization framework for the R&D of malaria health products

January 18, 2019 - 14:42 -- MESA Alliance

WHO is undertaking a consultative process to solicit inputs into a prioritization framework for the research and development (R&D) of malaria health products. A draft report “Analysis of Malaria R&D Priorities” identifies five key challenges that represent threats or barriers to achieving the WHO Global Technical Strategy for Malaria 2016–2030 goals. This early copy of the report is being shared at a time when WHO is exploring how best to guide and support the development of priority solutions to meet public health needs.

WHO welcomes feedback on this draft report until 28 February 2019, including the correction of errors or omissions, updates to product development pipelines, and perspectives on the approach to prioritization.

New from MESA: Critical global gathering "Innovate for Collective Impact to End Malaria"

January 10, 2019 - 18:02 -- MESA Alliance

MESA co-hosting a critical global gathering in response to the latest disease reality and future innovation and financing needs

The MESA Alliance is set to co-host an invite-only scientific symposium entitled, “Innovate for Collective Impact to End Malaria”, on Friday, January 11, 2019, at the National Academy of Sciences in Washington, DC, USA. Its core objective is to frame a response to the 2018 World Malaria Report and to develop innovative approaches to collectively bridge critical issues in malaria eradication spanning research, financing, and implementation.

World Malaria Report 2018 is out!

November 20, 2018 - 16:22 -- Ingeborg van Schayk

This year's report shows that after an unprecedented period of success in global malaria control, progress has stalled. Data from 2015–2017 highlight that no significant progress in reducing global malaria cases was made in this period. There were an estimated 219 million cases and 435 000 related deaths in 2017.

The World malaria report 2018 draws on data from 91 countries and areas with ongoing malaria transmission. The information is supplemented by data from national household surveys and databases held by other organizations.

News: Texas Biomed scientists researching Ebola-malaria connection

October 22, 2018 - 15:00 -- Malaria World

TEXAS BIOMEDICAL RESEARCH INSTITUTE - PUBLIC RELEASE: 17-OCT-2018

More than 150 people have died from Ebola virus disease in 2018

 

San Antonio, Texas (October 17, 2018) -- Ebola virus is a continuing threat in Central and West Africa, with an outbreak currently taking place in the Democratic Republic of Congo. The disease kills up to 90% of the people who get infected, and more than 150 people have died from Ebola so far this year. The factors that determine who is susceptible to Ebola infection and who is not are still a mystery.

Significance of time to clinical recurrence in vivax malaria

October 12, 2018 - 10:55 -- Miles Markus

The amount of time that passes between a symptomatic vivax malarial episode and a subsequent recurrence has in the past often been regarded as an indication as to whether the recurrence is a relapse (hypnozoite origin) or a recrudescence (merozoite origin). It should be noted that in the light of new knowledge and understanding, the time factor is not a valid criterion. (Link to first paper). (Link to second paper).

Artemisia et Paludisme: la santé entre les mains des Africains

September 29, 2018 - 13:13 -- Pierre Lutgen

The French periodical PARIS MATCH published an extensive document on the fight against malaria with Artemisia annua and Artemisia afra. And the dubious role WHO plays.

https://www.parismatch.com/Actu/Sante/Artemisia-et-paludisme-la-sante-entre-les-mains-des-Africains-1577250

Malaria elimination problem

September 13, 2018 - 23:36 -- Miles Markus

We talk about asymptomatic, submicroscopic plasmodial infections as potentially being a threat to the elimination of malaria. This is, of course, partly because such infections are not normally treated; especially not in rural endemic areas where laboratory facilities are limited. An aggravation of the situation is when parasitaemias are so low that they cannot be detected by molecular diagnosis (where available) either. But obstacles to elimination are probably even greater than has been realized.

Eliminating malaria transmission in the Asia-Pacific region

September 13, 2018 - 11:26 -- Malaria World



Progress in malaria elimination across the Asia-Pacific is at critical cross-roads, threatened by the spread of multidrug resistant falciparum malaria and continued transmission among marginalized and mobile populations living and working in conditions beyond the reach of traditional malaria control interventions. 

How can we promote more active dialogue on malaria?

September 10, 2018 - 13:27 -- William Jobin

Dear colleagues,
As you probably do, I eagerly check MalariaWorld almost every day, and when I have something to contribute, post a blog or comment. But I am disappointed by the lack of responses to my contributions, or to those from all of you. How can we improve this?
Since almost 10,000 people are connected thru MalariaWorld, we might make real progress if we can all contribute. I want to end malaria sooner, not later. Do you agree?
Bill Jobin

Malaria prophylaxis with amiodarone (cordarone).

August 25, 2018 - 17:49 -- Pierre Lutgen

Amiodarone which is used to control irregular heartbeat also has a protective effect in malaria. It triggers eryptosis and the clearance of malaria infected erythrocytes. In Plasmodium berghei infected mice amiodarone injections increased the survival. It is interesting to note that amiodarone is also active against other tropical diseases like Chagas or Leishmaniasis, both in vitro and in vivo, probably by disrupting the parasites' Ca(2+) homeostasis,

Kitchen Sink Strategy and portfolio approach

August 17, 2018 - 14:09 -- William Jobin

It is valuable and refreshing to see contributions to strategies for malaria suppression in Africa from other disciplines, such as economics. Killeen and Reed pointed out that the portfolio effect cushions mosquito populations and malaria transmission against vector control interventions.(Killeen GF, Reed TE. Malar J. 2018 Aug 10;17(1):291. doi: 10.1186/s12936-018-2441-z.) Thus it must be considered when planning a strategy for Africa.

Transmission blocking vaccines fail, but Artemisia is very efficient

August 4, 2018 - 13:05 -- Pierre Lutgen

Vaccines blocking the invasion of malaria sporozoites failed so far, after 30 years of efforts, millions spent, and disastrous human clinical trials. The efforts and the millions are now focused on vaccines blocking transmission by gametocytes. The results are not yet encouraging but the updated Malaria Vaccine Technology Roadmap foresees that there will be a TBV vaccine available in 2030. The update was necessary as the program launched by WHO in 2000 ( TDR/RBM/MAL/VAC/2000.1) has not yet progressed very far.

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