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New from MESA: Critical global gathering "Innovate for Collective Impact to End Malaria"

January 10, 2019 - 18:02 -- MESA Alliance

MESA co-hosting a critical global gathering in response to the latest disease reality and future innovation and financing needs

The MESA Alliance is set to co-host an invite-only scientific symposium entitled, “Innovate for Collective Impact to End Malaria”, on Friday, January 11, 2019, at the National Academy of Sciences in Washington, DC, USA. Its core objective is to frame a response to the 2018 World Malaria Report and to develop innovative approaches to collectively bridge critical issues in malaria eradication spanning research, financing, and implementation.

World Malaria Report 2018 is out!

November 20, 2018 - 16:22 -- Ingeborg van Schayk

This year's report shows that after an unprecedented period of success in global malaria control, progress has stalled. Data from 2015–2017 highlight that no significant progress in reducing global malaria cases was made in this period. There were an estimated 219 million cases and 435 000 related deaths in 2017.

The World malaria report 2018 draws on data from 91 countries and areas with ongoing malaria transmission. The information is supplemented by data from national household surveys and databases held by other organizations.

News: Texas Biomed scientists researching Ebola-malaria connection

October 22, 2018 - 15:00 -- Malaria World


More than 150 people have died from Ebola virus disease in 2018


San Antonio, Texas (October 17, 2018) -- Ebola virus is a continuing threat in Central and West Africa, with an outbreak currently taking place in the Democratic Republic of Congo. The disease kills up to 90% of the people who get infected, and more than 150 people have died from Ebola so far this year. The factors that determine who is susceptible to Ebola infection and who is not are still a mystery.

Significance of time to clinical recurrence in vivax malaria

October 12, 2018 - 10:55 -- Miles Markus

The amount of time that passes between a symptomatic vivax malarial episode and a subsequent recurrence has in the past often been regarded as an indication as to whether the recurrence is a relapse (hypnozoite origin) or a recrudescence (merozoite origin). It should be noted that in the light of new knowledge and understanding, the time factor is not a valid criterion. (Link to first paper). (Link to second paper).

Artemisia et Paludisme: la santé entre les mains des Africains

September 29, 2018 - 13:13 -- Pierre Lutgen

The French periodical PARIS MATCH published an extensive document on the fight against malaria with Artemisia annua and Artemisia afra. And the dubious role WHO plays.

Malaria elimination problem

September 13, 2018 - 23:36 -- Miles Markus

We talk about asymptomatic, submicroscopic plasmodial infections as potentially being a threat to the elimination of malaria. This is, of course, partly because such infections are not normally treated; especially not in rural endemic areas where laboratory facilities are limited. An aggravation of the situation is when parasitaemias are so low that they cannot be detected by molecular diagnosis (where available) either. But obstacles to elimination are probably even greater than has been realized.

Eliminating malaria transmission in the Asia-Pacific region

September 13, 2018 - 11:26 -- Malaria World

Progress in malaria elimination across the Asia-Pacific is at critical cross-roads, threatened by the spread of multidrug resistant falciparum malaria and continued transmission among marginalized and mobile populations living and working in conditions beyond the reach of traditional malaria control interventions. 

How can we promote more active dialogue on malaria?

September 10, 2018 - 13:27 -- William Jobin

Dear colleagues,
As you probably do, I eagerly check MalariaWorld almost every day, and when I have something to contribute, post a blog or comment. But I am disappointed by the lack of responses to my contributions, or to those from all of you. How can we improve this?
Since almost 10,000 people are connected thru MalariaWorld, we might make real progress if we can all contribute. I want to end malaria sooner, not later. Do you agree?
Bill Jobin

Malaria prophylaxis with amiodarone (cordarone).

August 25, 2018 - 17:49 -- Pierre Lutgen

Amiodarone which is used to control irregular heartbeat also has a protective effect in malaria. It triggers eryptosis and the clearance of malaria infected erythrocytes. In Plasmodium berghei infected mice amiodarone injections increased the survival. It is interesting to note that amiodarone is also active against other tropical diseases like Chagas or Leishmaniasis, both in vitro and in vivo, probably by disrupting the parasites' Ca(2+) homeostasis,

Kitchen Sink Strategy and portfolio approach

August 17, 2018 - 14:09 -- William Jobin

It is valuable and refreshing to see contributions to strategies for malaria suppression in Africa from other disciplines, such as economics. Killeen and Reed pointed out that the portfolio effect cushions mosquito populations and malaria transmission against vector control interventions.(Killeen GF, Reed TE. Malar J. 2018 Aug 10;17(1):291. doi: 10.1186/s12936-018-2441-z.) Thus it must be considered when planning a strategy for Africa.

Transmission blocking vaccines fail, but Artemisia is very efficient

August 4, 2018 - 13:05 -- Pierre Lutgen

Vaccines blocking the invasion of malaria sporozoites failed so far, after 30 years of efforts, millions spent, and disastrous human clinical trials. The efforts and the millions are now focused on vaccines blocking transmission by gametocytes. The results are not yet encouraging but the updated Malaria Vaccine Technology Roadmap foresees that there will be a TBV vaccine available in 2030. The update was necessary as the program launched by WHO in 2000 ( TDR/RBM/MAL/VAC/2000.1) has not yet progressed very far.

Book: Towards Malaria Elimination - A leap forward (Open Access)

July 23, 2018 - 11:22 -- Malaria World

Edited by Sylvie Manguin and  Dr Vas Dev

Published: July 18th 2018

DOI: 10.5772/intechopen.69750
ISBN: 978-1-78923-551-7
Print ISBN: 978-1-78923-550-0

Click here  to read more about this Open access peer-reviewed Edited volume

Plasmodium vivax comment links

July 20, 2018 - 22:50 -- Miles Markus

The two links below did not come up in the original "Comment" on a paper but should do so in this "Blog" version, which appears in full below. It was speculated in detail for the first time in two recent publications (particularly the second one) that in addition to a hypnozoite origin of relapse-like vivax recurrences, parasites in bone marrow might be a source. (Link to first paper). (Link to second paper).

Stability of Artemisia plants after ageing

July 11, 2018 - 19:05 -- Pierre Lutgen

In 2001 WHO posted a statement on their home page, without signatures, without references: « Due to the instability of artemisinin in raw materials of Artemisia annua L, the leaves need to be stored in cool conditions — preferably below 20°C. Most malaria endemic countries have warm climates and people generally lack access to refrigeration, so it is difficult for patients to keep artemisinin-containing tea bags under 20°C in their homes” A statement not substantiated by scientific papers. Cui bono?

Our associations immediately gathered available data which prove the contrary


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