World Malaria Day 2017 Statement from Dr. Kesetebirhan Admasu Chief Executive Officer, Roll Back Malaria Partnership
We can be the generation to end malaria for good
April 25, 2017 – (Geneva, Switzerland)
Bigpharma-WHO-Gates desperately try to ignore peer reviewed scientific papers documenting the spread of ACT resistance in at least 12 African countries (see “Artemisinin resistance In Africa” www.malariaworld.org).
Several medical teams in Africa have demonstrated in randomized, double blind clinical trials that Artemisia infusions are powerful in therapy and prophylaxis (see “Breaking news from clinical trials with Artemisia plants” www.malariaworld.org).
The Eltahir group at MIT has recently published a pioneering study which makes it possible to plan resettlement and new villages in ways which will permanently minimize malaria transmission, because of ecological design. This is especially valuable for engineers planning resettlement communities related to large reservoirs and irrigation systems.
Such safe designs reduce the need for the ephemeral methods based on drugs, bednets and insecticides.
The report is:
A thesis from Sudan presents troubling facts
Hassan Humeida. Der Verlauf von Malaria bei Patienten mit Diabetes mellitus in Afrika - Feldforschungen im Zentral-Sudan - Dissertation. Giessen, Februar 2011 Justus-Liebig-Universität
In Mexico eight species of Artemisia have been described and among them just Artemisia ludoviciana has been empirically used in the treatment of intermittent fever (malaria). To know whether this Mexican Artemisia had antimalarial activity several in vivo experiments were performed, on mice infected by Plasmodium yoelii yoelii, in a four-day test scheme. The results of the in vivo experiments showed that the parasite reproduction was inhibited up to 98.6% at the fifth day.
28 February 2017, WHO
Members of the WHO Strategic Advisory Group (SAG) on malaria eradication recently convened in Geneva to review and define a set of work streams for the next 2-year period. The proposed scope of work is cross-cutting and spans a breadth of domains: biological, technical, financial, socio-economic, political and environmental.
27 February 2017
This blog was the result of my preparing for the recent RBM meeting in Geneva. I hope it will be useful for any of you on National Malaria Contol Programs. It is about the need for:
Formation of National Inter-Ministerial Boards for Malaria Control
Keystone Symposia malaria meeting in Kampala - Day 1
Sunday, 19 February 2017
Keystone Symposia malaria meeting in Kampala - Day 2
Monday, 20 February 2017
Keystone Symposia malaria meeting in Kampala - Day 3
Tuesday, 21 February 2017
Today’s morning session focused on tailoring packages of interventions to achieve the greatest impact in a specific setting.
Keystone Symposia malaria meeting in Kampala - Day 4
Wednesday, 22 February 2017
Today’s sessions focused on tools for malaria elimination, including promising vaccine and drug candidates, and novel vector control.
Keystone Symposia malaria meeting in Kampala - Day 5
Thursday, 23 February 2017
This morning was full of exciting science on the malaria parasite and its interaction with human and mosquito hosts. A common message from the presenters was the dynamic nature of parasite populations. Today’s parasites are adapting to evolutionary pressure and will not be the same in the future. As countries reach elimination, tools and strategies need to adapt as well.
received from Emile Schmitz, Athus
abstract
Caused not by racial or religious conflict, but by greed.
Every year WHO claims that the battle against malaria is won and that the number of malaria infections has been halved. Unfortunately, in several countries the disease is exploding. In Burundi the number of infections has increased from 4 716 152 in 2014 to 7 813 958 in 2016.
A recent mission of WHO to this country had to confess a complete failure of LLINs and ACTs.
4 years ago, a heated debate concerning malaria prophylaxis had been triggered on www.malariaworld.org. It concerned the very promising results obtained by Dr Patrick Ogwang, with an herbal product called Artavol, he had developed with the Ministry of Health in Uganda. Peer reviewed papers and press releases are easily found on internet.
Since the Trump administration came into office, there are real uncertainties about the long-standing US Presidential Malaria Initiaitive (the PMI), which I helped start in 2005. Firstly, the Administrator Tim Ziemer, who has given the Initiative real stability for 8 years, has resigned. Secondly it appears that the very conservative Newt Gingrich will take over USAID which funds the PMI within the US State Department. Gingrich is opposed to USAID and might dismantle it. Fortunately the new US Secty of State Rex Tillerson has gone on record as favoring the health programs of USAID.
Soniran Temidayo is a Nigerian PhD student. He travelled to Cornell University in the USA to study malaria drug resistance. Members of MalariaWorld donated money to make this life-changing experience possible for Soniran. A big thank you to you all to make this happen!
Oxidative stress as cause for the death of parasites was a major field of research some 30 years ago.
Dear there, we're excited to announce that the inaugural Malaria World Congress will be staged in Melbourne, Australia from July 1-5, 2018 and we now offer opportunities for Sponsorship, Exhibition, Advertising and Promotion.
Many Artemisia plants are called wormwood, because for thousands of years they have been used against worms. There have been some recent trials on animals, but most studies are in vitro.
Artemisia annua came under the spotlight during the Vietnam War. Viêt-Cong who operated in swamps and rain forests lost more soldiers by mosquito bites than by American bullets. Ho Chi Min turned to China for help. Researchers at the Chinese Institute of Material Medicine had found a region of China that reported no malaria cases, and when they investigated, they discovered that its people drank a decoction of Artemisia annua at the first symptoms of malaria.
Sugar feeding is a fundamental characteristic of mosquito life. It is the basic food of adult mosquitoes, as floral nectar or honeydew. It is the only nutrient consumed by males and probably the more common one for females, even if they need vertebrate blood to produce eggs. Malaria parasites also are dependent on glucose as a nutrient source. As Plasmodium has no capacity to store energy in the form of glycogen they rely entirely on an exogenous supply of glucose. The infected erythrocyte exhibits a substantial increase in its permeability to low molecular weight sugar.
The American Society of Tropical Medicine and Hygiene (ASTMH) hosted on November 16th a symposium to share key outcomes from the consultative process to update the malaria eradication research agenda (malERA). This review exercise, entitled “malERA Refresh”, has been led by the Malaria Eradication Scientific Alliance (MESA) with the participation of more than 180 experts around the world.
The WHO Malaria Report for 2016 mentions an alarming increase in the number of people no longer receiving protection from indoor spraying, and thus an increase in the number of people in endemic areas who have lost their immunity, due to previous intense spraying. For Africa, 10.5% of the populations were covered in 2010, but this had dropped to 5.7% by end of 2016.
It is important to note a recent report on the predicted impact of climate change on malaria in West Africa, by Teresa K. Yamana, Arne Bomblies and Elfatih A. B. Eltahir. 2016 in the Journal Nature, entitled "Climate change unlikely to increase malaria burden in West Africa." doi:10.1038/nclimate3085
“All things are poison and not without poison; only the dose makes a thing not a poison” Philippus Aureolus Theophrastus Bombastus von Hohenheim, also known as Paracelsus (1493–1541).
The "World Malaria Report 2016" draws on data from 91 countries and areas with ongoing malaria transmission. The information is supplemented by data from national household surveys and databases held by other organizations.
This year's report tracks progress towards the 2020 malaria goals of the "Global Technical Strategy for Malaria 2016-2030". It offers an in-depth analysis of trends in malaria control and elimination at global, regional and country levels.
I recommend the following recent publication for your reading on african malaria : Endo and Eltahir Malar J (2016) 15:578 DOI 10.1186/s12936-016-1633-7. The report is 'Environmental determinants of malaria transmission in African villages' by Noriko Endo and Elfatih A. B. Eltahir. You should also take a look at all the preceding publications of the Eltahir research group at MIT, which you can find if you look up the Eltahir research group on the web.
Preliminary note: In this document we will use indiscriminately the terms caryophyllene, alpha-caryophyllene, beta-caryophyllene, trans-caryopyllene, caryophyllene oxide, E-BCP
