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Podcast: Mass Drug Administration for Malaria Elimination in Zambia

July 10, 2020 - 12:41 -- Malaria Minute

Malaria Minute, 10 July 2020

Zambian study reveals that mass drug administration is safe, logistically feasible, accepted by communities, and effective in reducing malaria prevalence in the short term, and the Medicines for Malaria Venture launch Malaria Libre, an open-source drug discovery programme.
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Podcast: Extent of Insecticide Resistance in Africa Revealed

July 3, 2020 - 08:27 -- Malaria Minute

Malaria Minute, 03 July 2020

The prevalence of insecticide resistance increases in Africa and researchers find that the malaria parasite interferes with red blood cell development to ensure gametocyte maturation.

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Podcast: CDK5 Controls Atypical Replication of Plasmodium Parasite

June 26, 2020 - 14:49 -- Malaria Minute

Malaria Minute, 26 June 2020

CDK5 regulates atypical cell division in gametogony and is essential for DNA replication, and researchers assess whether two experimental vaccines can be combined to create a multistage vaccine against malaria.

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New from MESA: Towards a vaccine for Plasmodium vivax (ongoing)

June 25, 2020 - 12:45 -- MESA Alliance

Malaria-free world has been an ultimate goal embraced by WHO just decade after its foundation, however only 38 countries in temperate zone were able to eliminate malaria since then. In 2017, WHO Executive Board reasserted their full and firm support towards malaria eradication. The lancet commission on Malaria eradication has called for global experts and policy makers to agree upon an ambitious target of eradicating malaria by 2050.

New from MESA: Clinical Epidemiology of COVID-19 in Malaria Settings (ongoing)

June 25, 2020 - 12:35 -- MESA Alliance

As the novel coronavirus (COVID-19) pandemic continues to evolve it is essential to mitigate risk of increased incidence of other infectious diseases. In malaria-endemic regions, it will be important to understand the potential impact to epidemiological changes, trends in transmission, and clinical presentation of COVID-19 and malaria individually, and as co-infections.

Podcast: Recently Identified Quinoline Resistance Not Prevalent in Africa

June 15, 2020 - 10:51 -- Malaria Minute

Malaria Minute, 12 June 2020

New mutations to the quinoline drug family identified in South America and Asia are not prevalent in Africa and scientists evaluate a new field-based malaria blood test.

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Malaria inhibits Covid

June 10, 2020 - 17:50 -- Pierre Lutgen

 

The role of immunoglobulines E

In January 2020 we published together with 3 medical doctors from Africa: “Jérôme, Munyangi, Pascal Gisenya, Patrick Ogwang …Immunoglobulins in the skin lead to long-lasting prophylaxis. Pharm Pharmacol Int Journal, PPIJ, 2020, Issue1”, a paper which, if widely spread, could have had a dramatic impact on the way the present Covid-19 crisis is handled.

One of the key findings of their work is that immunoglobulins are higher in malaria endemic areas.

Podcast: Novel Malaria Drug Artefenomel Assessed Against Plasmodium vivax Infection

June 5, 2020 - 10:48 -- Malaria Minute

Malaria Minute, 5 June 2020

Artefenomel is assessed against Plasmodium vivax infection in humans to determine the minimum effective dose required for parasite clearance and a beta version of the Global Vector Hub is launched.

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Podcast: Spleen Plays Major Role in Plasmodium vivax Infection

May 29, 2020 - 10:52 -- Malaria Minute

Malaria Minute, 29 May 2020

The spleen plays a major role in the expression of P. vivax genes and the production of antigens associated with clinical protection, and scientists develop an AI that can detect Plasmodium infection in the blood.

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New from MESA: BioMalPar XVI: Biology and Pathology of the Malaria Parasite - Virtual

May 27, 2020 - 17:29 -- MESA Alliance

MESA Correspondents bring you cutting-edge coverage from the XVI BioMalPar virtual Conference “Biology and Pathology of the Malaria Parasite”

* MESA only reported the talks that had the approval of the speaker

Day 1 Monday 18th May 2020

Viruses, Malaria, Platelets and Artemisia

May 23, 2020 - 10:12 -- Pierre Lutgen

 

In my previous comments on www.malariaworld.org I alerted to the possibility that the widespread malaria infections in sub-Saharan Africa might provide a protection against the Covid virus. Trying to find an explanation for this observation might be important.

Podcast: Serological Tests for P. vivax Malaria Could Reduce Disease Transmission by 69%

May 15, 2020 - 19:35 -- Malaria Minute

Malaria Minute, 15 May 2020

Antibody tests for P. vivax malaria could reduce disease prevalence by up to 69% and scientists develop a sex-distorter gene drive that eliminates populations of mosquitoes in the lab.

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World Health Organization: Malaria eradication: benefits, future scenarios & feasibility

May 13, 2020 - 13:53 -- Malaria World

Report of the Strategic Advisory Group on Malaria Eradication

After a 3-year study of trends and future projects, WHO’s Strategic Advisory Group on Malaria Eradication has released a detailed report of its key findings and recommendations. The report builds on an executive summary published in August 2019. Members of the advisory group highlight 6 areas in the report that would underpin a successful malaria eradication effort:

1. reinforcing the Global technical strategy for malaria 2016-2030;
2. research & development for new tools;
3. access to affordable, high quality, people-centered health care and services;
4. adequate and sustained financing;
5. strengthened surveillance and response; and
6. engaging communities.

Community-based health care in the context of the COVID-19 pandemic

May 13, 2020 - 13:14 -- Malaria World

Community-based health care, including outreach and campaigns, in the context of the COVID-19 pandemic

Community-based health care is an essential part of primary care at all times; in the context of the COVID-19 pandemic, the distinct capacity of trusted community members for social engagement and delivering care where it is needed is ever more critical. This joint WHO, UNICEF and IFRC guidance addresses the role of community-based health care in the pandemic context. It includes practical recommendations for decision makers to help keep communities and health workers safe, to sustain essential services at the community level, and to ensure an effective response to COVID-19. Using this comprehensive and coordinated approach will help countries strengthen the resilience of community-based health services throughout the pandemic, into early recovery and beyond. Read more

Malaria still kills 1,100 a day. It can’t afford to lose resources to coronavirus

May 2, 2020 - 16:45 -- Fredros Okumu
As we mark this year’s World Malaria Day, we must emphasize the need for stronger health systems and sustained investments to more aggressively tackle malaria despite the coronavirus pandemic. Since the start of this year, malaria has killed about 100 times more people in Africa than COVID19. And today, there will be another 1100 malaria deaths, tomorrow the same number. If not addressed, there will be many more people indirectly killed by other diseases such as malaria, HIV and tuberculosis than by the outbreak itself.

Podcast: Combined Use of MDA and IRS Most Effective Way to Prevent Malaria Transmission

May 1, 2020 - 15:23 -- Malaria Minute

Malaria Minute, 1 May 2020

The combined use of mass drug administration and indoor residual spraying is the most effective way to reduce malaria prevalence in low malaria-endemic settings, and antibodies against PfGARP kill malaria-infected cells by inducing cell death.

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Keystone Symposia Interview: Malaria Challenges in the COVID-19 Era

April 28, 2020 - 15:36 -- Malaria World

Watch this exclusive interview & presentation by Dr. Pedro Alonso, WHO Global Malaria Programme Director, on how to tackle both of these global threats simultaneously. Brought to you by Keystone Symposia:

https://bit.ly/VKScovidmalaria

New from MESA: ASTMH 2019 Recap in the MESA Resouce Hub: How modeling has been used to provide technical support to national malaria control programs

April 28, 2020 - 14:35 -- MESA Alliance

Watch the presentations from this symposium, in which different experts talked about the importance of malaria modeling to understand the epidemiology of the disease and to help in the decision-making process by testing different scenarios.

Podcast: Gene Drive Outcomes Not Determined by Genetic Variation

April 24, 2020 - 14:30 -- Malaria Minute

Malaria Minute, 24 April 2020

Genetic variation would seem to have little impact on the success of gene drive interventions due to conserved Cas9 target sites in populations of Anopheles mosquitoes.

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Printed bed nets to protect underprivileged families in Uganda against malaria

April 23, 2020 - 16:57 -- Malaria World

In honour of World Malaria Day 2020

Care Plus® has donated 2000 impregnated printed bed nets to protect children in Uganda, one of the countries with the heaviest malaria burden in Africa. And this is just the start of the Buy One, Give One Program: for every Care Plus® impregnated net that is being sold, one free net is donated to people in need. It is one of the contributions that Care Plus® makes to the fight against malaria.

World Malaria Day 2020 - Zero malaria starts with me

April 23, 2020 - 14:04 -- Malaria World


 

In the lead-up to this year’s World Malaria Day, countries across the globe are in the throes of responding to the COVID-19 pandemic. While cases of the novel coronavirus in malaria-affected countries currently represent only a small proportion of the global total, the situation is evolving rapidly. WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria, using best practices to protect health workers and communities from COVID-19 infection.

World Health Organization: Tailoring malaria interventions in the COVID-19 response

April 22, 2020 - 15:34 -- Malaria World

During the COVID-19 pandemic, the malaria community must remain committed to supporting the prevention of malaria infection, illness and death through preventive and case management services, while maintaining a safe environment for patients, clients and staff. Deaths due to malaria and its comorbidities (anaemia, undernutrition, etc.) must continue to be prevented.

This document provides overarching principles as well as specific technical guidance for malaria interventions, including prevention of infection and disease, care and treatment of cases, testing, clinical services, supply chain and laboratory activities, during this time of the evolving COVID-19 pandemic. This document will be updated as the situation changes.

 

 

 

Don't forget to register for the free ePanel discussion “The Malaria Endgame” Free Virtual Event from Keystone Symposia!

April 16, 2020 - 12:52 -- Malaria World

REGISTER NOW for the April 22, 2020 free ePanel discussion featuring field leaders as they discuss the latest advances and innovative approaches to eliminate malaria—from vaccines, to genetically modified mosquitos and more. Discover new insights into disease biology, co-infections, epidemiology, and public health strategies in this virtual event, integrating basic research, medical advances and translational applications... Read more

Obituary: 'Have no Fear Wilkes is here' - Tony Wilkes (1933-2020)

April 15, 2020 - 08:48 -- Ingeborg van Schayk

Mr Tony Wilkes MIBiol was a field entomologist at the East African Malaria Institute in Amani, Tanzania (then called Tanganyika), from 1958 to 1964 working on the main vectors of malaria in Africa. Returning to the UK in 1965 he worked on the behaviour of mosquitoes at the University of Sussex’s School of Biology, moving to Imperial College, Silwood Park, Ascot, in 1980, working on sand fly biology and behaviour, and in 1987 to the London School of Hygiene and Tropical Medicine working on mosquito biology and control until his retirement in 1995. The obituary below was contributed by Dr. Derek Charlwood.

Podcast: Enhancing Fc-Dependent Effector Functions Could Improve Protective Efficacy of RTS,S

April 10, 2020 - 10:31 -- Malaria Minute

Malaria Minute, 10 April 2020

Enhancing antibody induction may improve the protective efficacy of RTS,S and researchers find that more gametocytes are produced when human infection is initiated by blood-stage parasites compared to mosquito bite.

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