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William Jobin's blog

What will become of the US Malaria Initiative now?

January 25, 2017 - 13:51 -- William Jobin
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Since the Trump administration came into office, there are real uncertainties about the long-standing US Presidential Malaria Initiaitive (the PMI), which I helped start in 2005. Firstly, the Administrator Tim Ziemer, who has given the Initiative real stability for 8 years, has resigned. Secondly it appears that the very conservative Newt Gingrich will take over USAID which funds the PMI within the US State Department. Gingrich is opposed to USAID and might dismantle it. Fortunately the new US Secty of State Rex Tillerson has gone on record as favoring the health programs of USAID.

More people caught in the Immunity Trap in 2016

December 20, 2016 - 21:15 -- William Jobin

The WHO Malaria Report for 2016 mentions an alarming increase in the number of people no longer receiving protection from indoor spraying, and thus an increase in the number of people in endemic areas who have lost their immunity, due to previous intense spraying. For Africa, 10.5% of the populations were covered in 2010, but this had dropped to 5.7% by end of 2016.

Eltahir Group predicts little adverse impact of climate change on malaria in West Africa

December 19, 2016 - 22:08 -- William Jobin

It is important to note a recent report on the predicted impact of climate change on malaria in West Africa, by Teresa K. Yamana, Arne Bomblies and Elfatih A. B. Eltahir. 2016 in the Journal Nature, entitled "Climate change unlikely to increase malaria burden in West Africa." doi:10.1038/nclimate3085

Eltahir research group at MIT on African malaria

December 7, 2016 - 21:21 -- William Jobin

I recommend the following recent publication for your reading on african malaria : Endo and Eltahir Malar J (2016) 15:578 DOI 10.1186/s12936-016-1633-7. The report is 'Environmental determinants of malaria transmission in African villages' by Noriko Endo and Elfatih A. B. Eltahir. You should also take a look at all the preceding publications of the Eltahir research group at MIT, which you can find if you look up the Eltahir research group on the web.

If malaria funding is so precarious, why not use permanent improvements in southern Africa ?

October 1, 2016 - 15:50 -- William Jobin

Malar J. 2016; 15: 419.
Published online 2016 Aug 18. doi: 10.1186/s12936-016-1470-8
PMCID: PMC4991067
Towards malaria elimination in the MOSASWA (Mozambique, South Africa and Swaziland) region
Authors:
Devanand Moonasar, Rajendra Maharaj, Simon Kunene, Baltazar Candrinho, Francisco Saute, Nyasatu Ntshalintshali, and Natashia Morris corresponding author.

When will we get off drugs and biocides ?

September 19, 2016 - 12:58 -- William Jobin

In a recent article about the spread of resistance to ACT in SE Asia, the authors recommend new drugs and better drug strategies:

'FEMS Microbiol Rev. 2016 Sep 8. pii: fuw037. [Epub ahead of print]
The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.
Woodrow CJ1, White NJ2'.

Similarly, multiple resistance of Anopheline vectors is supposedly to be met with more careful selection of insecticides!

PMI and Swiss Cheese

July 6, 2016 - 13:07 -- William Jobin

There is dangerous obstacle - we call it the Immunity Trap - in malaria prevention strategies which is most dangerous for countries which have relied on the ephemeral methods recommended by WHO and used by PMI, but which have not included permanent methods. In the 19 African countries in the US Presidential Malaria Initiative administered by the PMI for the last decade, of the 30 million who have lost their immunity, about half are also no longer protected by house spraying because of the high cost of new biocides.

Don't let the US PMI fall into the Immunity Trap

June 27, 2016 - 18:19 -- William Jobin

A decade ago, I helped the US Presidential Malaria Initiative get its start in Angola. Since then the Malaria Initiative (the US PMI) has expanded under Tim Ziemer to 19 African countries, protecting 30 million people. Consequently, over the last decade these 30 million people have lost their immunity to malaria. Now that might seem obvious and maybe a good thing. But since they live in regions where malaria is endemic, it raises a serious issue about durability of the PMI strategy.

The Resistance Treadmill

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