Malaria Minute, 12 June 2020
New mutations to the quinoline drug family identified in South America and Asia are not prevalent in Africa and scientists evaluate a new field-based malaria blood test.
Malaria Minute, 5 June 2020
Artefenomel is assessed against Plasmodium vivax infection in humans to determine the minimum effective dose required for parasite clearance and a beta version of the Global Vector Hub is launched.
Malaria Minute, 29 May 2020
The spleen plays a major role in the expression of P. vivax genes and the production of antigens associated with clinical protection, and scientists develop an AI that can detect Plasmodium infection in the blood.
Malaria Minute, 22 May 2020
The BioMalPar conference takes place online and the synchronisation of Plasmodium infection is controlled by the parasite’s own internal clock.
Malaria Minute, 15 May 2020
Antibody tests for P. vivax malaria could reduce disease prevalence by up to 69% and scientists develop a sex-distorter gene drive that eliminates populations of mosquitoes in the lab.
Malaria Minute, 8 May 2020
Scientists find that microsporidia MB stops malaria transmission in Anopheles arabiensis mosquitoes by disrupting oocyst formation.
Malaria Minute, 1 May 2020
The combined use of mass drug administration and indoor residual spraying is the most effective way to reduce malaria prevalence in low malaria-endemic settings, and antibodies against PfGARP kill malaria-infected cells by inducing cell death.
Malaria Minute, 24 April 2020
Genetic variation would seem to have little impact on the success of gene drive interventions due to conserved Cas9 target sites in populations of Anopheles mosquitoes.
Malaria Minute, 17 April 2020
Results from the first human trial of the novel antimalarial drug SJ733 are published in The Lancet.
Malaria Minute, 10 April 2020
Enhancing antibody induction may improve the protective efficacy of RTS,S and researchers find that more gametocytes are produced when human infection is initiated by blood-stage parasites compared to mosquito bite.
Malaria Minute, 03 April 2020
The FDA issue an emergency use authorisation for the anti-malarial drug chloroquine, allowing for it to be used to treat certain hospitalised patients with COVID-19.
Malaria Minute, 27 March 2020
Scientists evaluate chloroquine as a potential treatment for the coronavirus and, as it continues to spread around the world, a report in The Lancet stresses the need for preparedness in malaria-endemic regions.
Malaria Minute, 20 March 2020
A protein called PIMMS43 enables the malaria parasite to evade the mosquito’s immune system and scientists describe a highly conserved protein in the malaria parasite that is essential for the invasion of red blood cells.
Malaria Minute, 14 March 2020
The global supply chain linked to deforestation leads to an increase in malaria prevalence and scientists identify the mechanism of action of clemastine, an antihistamine that inhibits multiple stages of the malaria parasite’s lifecycle.
Malaria Minute, 7 March 2020
Researchers target Plasmepsin proteases as resistance to ACT grows, and the process by which the malaria parasite suppresses the immune system is detailed by scientists.
Malaria Minute, 28 February 2020
The Molecular Approaches to Malaria Conference takes place in Australia, and a study into the long-term side effects of antimalarials could not identify any sufficient evidence of association between malaria prophylaxis and adverse health effects.
Malaria Minute, 21 February 2020
Scientists identify two proteins that are essential for the malaria parasite’s genetic malleability, and the substance responsible for ‘rosette’ formation in human red blood cells is identified.
Malaria Minute, 14 February 2020
Scientists find that the EphA2 protein mediates a critical stage of cerebral malaria and data scientists construct a statistical modelling framework of malaria seasonality in Madagascar.
Malaria Minute, 7 February 2020
Scientists identify the process by which the malaria parasite imports sugar, a potential target for inhibiting parasitic development.
Malaria Minute, 31 January 2020
Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.
Malaria Minute, 31 January 2020
Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.
Malaria Minute, 24 January 2020
Malaria antibodies in pregnant women may be a marker of exposure, not protection, from malaria and a combination of antimalarial drugs is less efficacious than if used in tandem.
Malaria Minute, 17 January 2020
Single-cell genome processing yields surprising results about the origin of complex malaria and study finds that the management of malaria in children at schools is ineffective.
Malaria Minute, 10 January 2020
A mechanism of resistance to artemisinin is identified and researchers find that breastfeeding could help to prevent malaria in babies.
Malaria Minute, 3 January 2020
Researchers from the Pasteur Institute discover molecules that can kill the malaria parasite and researchers from LSTM identify a resistance mechanism for insecticides used on bed nets.
Malaria Minute, 27 December 2019
Gene drives prove most efficient in the introduction of a transgene in populations of Anopheles stephensi mosquitoes.
Malaria Minute, 20 December 2019
Researchers from the Walter and Eliza Hall institute identify a new drug which blocks plasmepsin, a critical enzyme in gametocyte production.
Malaria Minute, 13 December 2019
The Gavi Alliance grant an additional $11.6 million in funding to extend clinical trials of the RTS,S vaccine.
Malaria Minute, 6 December 2019
The WHO publish their annual World Malaria Report which, this year, places emphasis on protecting pregnant women and children from malaria.
Malaria Minute, 29 November 2019
A genome of the European lineage of P. vivax malaria is generated by scientists and engineers develop an artificially-intelligent microscope for malaria diagnosis.
