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Asia Pacific Malaria Elimination Meeting Held in Sabah, Malaysia

May 26, 2011 - 21:00 -- The Global Heal...

The third annual meeting of the Asia Pacific Malaria Elimination Network (APMEN) was held May 9-12, 2011 in Kota Kinabalu, Sabah, Malaysia. The meeting celebrated the on-going efforts within the region to reduce the scourge of malaria, to share experiences on how countries are working towards elimination of malaria, and work collaboratively on projects in research, capacity building, and advocacy. In attendance were 80 representatives from the 11 Country Partners and research and partner institutions from the region, including the WHO.

The conspiracies behind malaria eradication in Africa must stop!

May 11, 2011 - 12:07 -- Stephen Yeboah

Malaria continues to threaten the lives of people despite huge funds made available to fight this preventable disease. According to the 2010 report “Breaking the Cycle: Saving Lives and Protecting the Future” by the Department for International Development (DFID), global funding for malaria has increased from $0.733 billion in 2006 to $1.94 billion in 2009. Despite the increasing funds for malaria control, the disease still kills about 800,000 people each year with the Africa [Sub-Saharan region] being the hardest hit [90 percent].

Outcome of Poster Session on Innovative Alternatives to DDT held alongside the 5. Meeting of the Stockholm Convention

May 10, 2011 - 08:46 -- Stefanie Keller

Biovision, in support of the implementation of the Global Alliance for Alternatives to DDT, has organised a series of posters to present alternatives to DDT. The posters on innovative products, methods and alternative strategies for malaria vector control have been displayed alongside the Fifth Meeting of the Conference of the Parties to the Stockholm Convention.

APMEN welcomes two new partners: Thailand and the London School of Hygiene and Tropical Medicine

April 15, 2011 - 18:36 -- The Global Heal...

The Asia Pacific Malaria Elimination Network (APMEN) announced that two new partners have joined the Network – Thailand and the London School of Hygiene and Tropical Medicine. Thailand is the eleventh County Partner to join the Network. Thailand has made significant progress over the last 10 years, reducing cases by 75% from 2000 to 2009, and has developed a strategy of sub-national malaria elimination, focusing on the central and eastern portions of the country. The London School of Hygiene and Tropical Medicine (LSHTM) joins the ranks of the Network’s 21 Partner Institutions.

Water resources development and malaria transmission in Sub Saharan Africa: What is needed?

April 15, 2011 - 09:03 -- Solomon Kibret
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In recent years, there seems to have a boost in construction of large dams and irrigation schemes in sub-saharan Africa, mainly in Ethiopia. With recognition of such infrastructures to ensure economic development and allevate poverty, Ethiopia is building large dams and constructing large irrigation schemes in parts of the countries where malaria is endemic. However, such water infrastructures have been shown to intensify malaria transsmission in communities living close to water storages.

A better method for estimating the real strength of LLIN

April 14, 2011 - 11:55 -- Rune Bosselmann

Measuring bursting strength is the standard method for evaluating mosquito net strength. However, in real life use scenarios of nets these are rarely exposed to the kind of strain they are exposed to in this test. It would correspond to, more or less, if you were to grab on to a net by the hands, uniformly and without penetrating the mesh with your fingers, and pull the net apart. Few people can do that. However, if you put the netting on a nail at one end and pull with your hand at the other, a hole will be ripped with very little effort.

PPAR-gamma agonists for the treatment of cerebral malaria - tweaking the host response to save brains

April 7, 2011 - 14:48 -- Lena Serghides

Even when treated with the best anti-malaria drugs 1 in 5 children with cerebral malaria will die, and of the survivors 1 in 4 will be left with long-term learning and memory impairment. This is because the host response to the infection plays as much a role in contributing to the development of cerebral malaria as does the parasite itself. Although conventional therapies for malaria can be very effective at eliminating the parasite, they do little to modulate the host response.

A novel antimalarial treatment based on engineered antibodies

April 6, 2011 - 16:06 -- Horacio Bach

The treatment of malaria has been hampered by the appearance of parasites resistant to conventional malaria drugs. Disease progression relies on the adherence of parasite-containing red blood cells to the blood vessel tissues. This condition allows the parasite to evade its clearance from the blood. Current treatments focus on killing the parasites inside of infected red blood cells but resistant strains have evolved with the ability to pump the drugs out of the erythrocytes.

Price Subsidy Schemes for Artemisinin-Based Combination Therapies (ACTs): Do They Work?

April 5, 2011 - 19:26 -- The Global Heal...

Although ACTs are recommended as first line treatment for uncomplicated malaria, actual use of ACT is very limited, partly due to its high price in pharmacies and retail stores. The Affordable Medicines Facility-malaria (AMFm), a donor-funded global price subsidy, has been proposed as a strategy to increase ACT use in malaria-endemic countries. Given that donor-supported ACT subsidy schemes are costly, it is crucial to ensure that they have their intended impact.

Where Malaria Wins

March 24, 2011 - 14:59 -- Patrick Sampao

For most part my colleagues Stella, Kabogo and I are often holed up in Malaria World, Nairobi office digging through hundreds of journals to pick out anything relevant to the “Malaria World”. Over the past weeks we have held discussions of what really happens out there, how is the war against malaria coming along? Are we loosing or winning?

Experts in favour of tighter rules for DDT use against malaria

February 2, 2011 - 08:48 -- Guest (not verified)

UN-Experts on DDT recommend stricter rules when DDT is used for malaria vector control. Their report published ahead of the 5th Conference of the Parties to the Stockholm Convention (COP-5, Geneva April 25-29, 2011), shows more and more concern about effects of DDT on human health as well as on the environment. Their report was released last week, showing that the international community might be moving towards new rules on the use of DDT.

entrepreneurship in malaria

January 14, 2011 - 09:40 -- Marit Farenhorst

2011 is going to be an exciting year! I am venturing out of the academic boundaries (i.e. Universities) and will make my way to entrepreneurship. Together with 2 established colleagues I'm setting up a new business/research institute in The Neterlands. Our aim is to create innovative vector control solutions, in particular for disease-endemic countries.

The Green House Phenomenon

January 4, 2011 - 15:16 -- Patrick Sampao

Late last year, I was told of a newly discovered alternative use for mosquito nets that residents from a locality in Muranga, a district in Central Kenya, have embraced.  My informant called it the green house phenomena. I wanted to see the “green houses” for myself before saying much about them. Last weekend I set out to see what that was all about.

Report on the encounter “DDT controversy in the face of safe and effective malaria vector control”

December 20, 2010 - 13:25 -- Stefanie Keller

On November 12, an encounter on “DDT controversy in the face of safe and effective malaria vector control” was held in Geneva, organized by Media 21 and hosted by Biovision, icipe and the Millennium Institute with the support of the Secretariat of the Stockholm Convention. This blog summarizes the most important arguments and statements made by the panellists and the audience regarding the use of DDT in malaria vector control.

Large-Scale Malaria Treatment in the Private Sector: A Case Study of the Cambodian Experience

December 14, 2010 - 21:18 -- The Global Heal...

The UCSF Global Health Group’s (GHG) Health Systems Initiative supports a community of practice for National Malaria Control Program Managers and others around the private sector provision of ACTs in light of the AMFm. It recently published Large-Scale Malaria Treatment in the Private Sector: A Case Study of the Cambodian Experience, a case study aimed to inform the efforts of countries embarking on private sector malaria treatment initiatives.

Insecticidal Bednets for the Fight Against Malaria – Present Time and Near Future

December 1, 2010 - 07:46 -- Rune Bosselmann

Malaria is to-day a tropical disease that especially has major impact in Subsahelian Africa. The current largescale campaign against malaria focuses on better first line use of medication and prevention: (1) the combined use of an Artimisin derivative and one of several synthetic anti-malarials; and (2) the use of insecticidal bednets for transmission prevention, since the disease is transmitted between humans by female mosquitoes.

My introduction

October 31, 2010 - 06:09 -- Ron Marchand

My name is Ron Marchand (1951), Dutch, biologist by training and I started to work in malaria entomology in 1978 with studies on the mating behaviour and biochemical identification of sibling species of the An. gambiae Group in Tanzania. For a too short time after that I was involved in a prematurely ended research programme to develop genetic control methods for malaria vectors in the Netherlands.

The Lancet Series on Malaria Elimination

October 29, 2010 - 04:20 -- The Global Heal...

UCSF Experts Outline New Strategy to Eliminate Malaria

November 5, 2010 - Global health experts at the University of California, San Francisco (UCSF) have outlined a new strategy and action plan to help countries eliminate malaria and bring the world closer to global eradication of the deadly disease.

PhD Thesis: Bahavioural, ecological and genetic determinants of mating and gene flow in African malaria mosquitoes

October 27, 2010 - 14:39 -- Kija Nghabi
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Kija R.N. Ng’habi

This thesis specifically investigated (i) the effect of larval density and nutrition on the mating competitiveness of adult male Anopheles gambiae s.s mosquitoes (ii) compared the physiological fitness of male Anopheles gambiae mosquitoes between laboratory and field populations, (iii) the potential for establishing a self-replicating Anopheles arabiensis population in an enclosed semi-natural environment and observing its genetic variation over time, (iv) the development of a PCR-based method for assessing male mating success among inseminated female An. gambiae and (v) the population genetic structure of An. gambiae s. l. along the Kilombero valley (southern Tanzania).

The Good and the Bad Guys.

October 27, 2010 - 11:09 -- Patrick Sampao

After a long stint, I finally managed to go home for a visit last weekend. Its been raining in Nairobi over the last few days so there are puddles of water here and there and my home is no exception. You already know am going to talk about mosquitoes and malaria well yes I am.

A geography of resistance mutations in Africa

September 8, 2010 - 11:02 -- Cally Roper

We have collated and mapped reports of the dhps K540E mutation in Africa. The mutation is a marker of resistance to SP (Fansidar) and has a remarkable geographical distribution.

Check the interactive map http://www.drugresistancemaps.org/maps/dhps540/ to see the distribution and check that your study has been included.

Inbarani Naidoo and Cally Roper

Mosquito eradication – a fight against wind mills

August 18, 2010 - 16:55 -- Lena Hulden

Human has been successful in the eradication of species as the moa or the dront. The war against mosquitoes started in the beginning of the 20th century and more effort has been put in it than in any other eradication project. Still it has not been very effective. Sardinia was practically covered with DDT after WWII, but it is not unusual to stumble on Anopheles labranchiae there again.

Mosquito monitoring in the Subarctic

August 18, 2010 - 16:39 -- Lena Hulden
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This season I have together with my husband been monitoring bloodsucking insects at the reindeer research station in Kaamanen, Lapland Finland (69˚ N lat.). The station is about 150 km from Barents Sea and the snow smelts in late May. The ground is frozen from October/November until May/June and the depth of the frost is 80 cm. The staff at the station is really friendly and helpful.

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