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Podcast: Microneedle Patches the Future of Malaria Diagnosis

November 6, 2020 - 15:32 -- Malaria Minute

Malaria Minute, 6 November 2020
A new diagnostic tool using microneedles eliminates the need for a fingerprick, and researchers develop a more efficient gene-drive system that overcomes the challenge of genetic resistance.
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New from MESA: Housing improvements to reduce malaria transmission - A conversation with Dr Lucy Tusting

November 4, 2020 - 15:29 -- MESA Alliance

Photograph credits © Jakob Knudsen 2019: left - Kibera, Nairobi, Kenya; right - Drone photo, suburb of Tanga, Tanzania. Houses constructed over an estimated 20 years. The oldest roofs are rusty, the newest in  bright colours. Also visible are foundations and half built houses. People build in a long, incremental process whenever money is available.

Dr Lucy Tusting, Assistant Professor at the London School of Hygiene & Tropical Medicine and co-director of the BOVA network, discusses the relationship between housing, urbanisation and health and how housing improvements may reduce malaria transmission.

Importance of Serology in Plasmodium vivax Infection

November 4, 2020 - 01:31 -- Miles Markus

Attention has been drawn to the use of serology for revealing subclinical Plasmodium vivax malaria that can lead to ongoing transmission of the disease in human communities if parasite carriers are not treated [1].

Podcast: How Malaria Parasite Survive During the Dry Season

October 30, 2020 - 14:58 -- Malaria Minute

Malaria Minute, 30 October 2020
Researchers find that a change in parasite behaviour may help them survive in the human host during the dry season, and the importance of preventative malaria treatment in school children is demonstrated in a recent review.
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CLOSED: Call for applications: Wellcome Investigator Awards in Science

October 29, 2020 - 17:25 -- Malaria World

Career stage: Leading a research programme
Where your host organisation is based: UK, Republic of Ireland, Low- or middle-income countries (apart from India and mainland China)
Type of researcher: Basic, Clinical, Public health
Level of funding: Flexible funding, up to around £3 million. Salary isn’t provided.
Duration of funding: Flexible duration, up to 7 years

New from MESA: Meet the MESA Correspondents that will cover the virtual ASTMH 2020 Annual Meeting

October 29, 2020 - 10:04 -- MESA Alliance

 

The MESA Correspondent volunteers report on the latest in malaria research from conferences around the world. The synopses are shared online, enabling people who could not attend the meeting to read about the latest advances. The MESA Correspondents Program is a collaboration between MESA and the conference organizers.

Podcast: Treatment Delays Increase Chances of Developing Severe Malaria

October 23, 2020 - 15:07 -- Malaria Minute

Malaria Minute, 23 October 2020
Researchers examine the relationship between treatment delay and the development of severe malaria and targeting extra-chromosomal DNA belonging to the malaria parasite could help to prevent the development of antimalarial resistance.
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A catholic organisation in Austria dislikes film on herbal medicine.

October 22, 2020 - 11:58 -- Pierre Lutgen

The film « The Fever » of Katharina Weingärtner was released on September 25 and is well received by public and media. It depicts the fight of African universities and grassroot organizations for local solutions and remedies against the sharp increase in malaria fatalities over the recent years. 500 000 more in 2020 according to WHO !

Malaria, IgE, COVID-19, and Vaccines

October 21, 2020 - 00:16 -- Miles Markus

A Blog by Pierre Lutgen in the MalariaWorld Newsletter (https://malariaworld.org/search/site/Malaria%20inhibits%20Covid) refers to the high overall Immunoglobulin E (IgE) levels that have been found in human populations in areas where malaria is endemic. Further to what is explained in his Blog, but on a different subject:

New from MESA: Call for Experts for the MESA Correspondents Program

October 20, 2020 - 16:02 -- MESA Alliance

MESA is seeking malaria experts in all technical areas that wish to contribute to the Correspondents Program as Senior Editors by mentoring and supporting the MESA Correspondents volunteers that will cover the ASTMH Annual Meeting. If you want to be involved or would like further details, please contact us at mesa@isglobal.org.

Podcast: Molecules That Aid Parasite Movement Could Provide New Drug Targets

October 16, 2020 - 13:39 -- Malaria Minute

Malaria Minute, 16 October 2020
Scientists characterise Myosin A motor to assess its importance in parasite mobility and researchers stress the need to evaluate both the quality and quantity of induced antibodies to determine vaccine efficacy.
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Podcast: New Insight Into Heat Resistance of Plasmodium Parasites

October 9, 2020 - 14:33 -- Malaria Minute

Malaria Minute, 9 October 2020
Researchers detail the role of PI(3)P in preventing heat-shock induced cell death and the BK-SE36 adjuvanted malaria vaccine is found to be safe, well-tolerated and protective in clinical trials.
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Podcast: Surface Tension Key to Dantu Blood Group Protection

September 28, 2020 - 19:20 -- Malaria Minute

Malaria Minute, 25 September 2020
The secrets to the Dantu blood group’s innate protection from malaria are revealed, researchers identify the protein needed for efficiency egress of rodent malaria from the liver, and a letter Trends in Parasitology defends the mosquito.
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Open Access Book - Vector Biology and Control: An Update for Malaria Elimination Initiative in India

September 19, 2020 - 10:54 -- Malaria World

Edited by Vas Dev, M.Sc. (Hons.), Ph.D (Notre Dame), FNASc
The National Academy of Sciences, India 2020

This book was commissioned by the National Academy of Sciences, India to spread the current knowledge of the mosquito vectors of human malaria and control options in different geo-epidemiological risk-zones of India. Given the clarion call for malaria elimination by 2027, understanding vector bionomics in the changing ecological context is of paramount importance to formulate species-specific intervention strategies to disrupt transmission of malaria. India is fast accelerating towards the ambitious goal of malaria elimination presenting a window of opportunity for scaling up interventions and developing stronger health systems for universal coverage. This book is of immediate relevance to programme/policy managers and researchers alike, reinforcing continued research on innovative technologies for sustainable control helping end transmission for good in the foreseeable future towards envious goal of a malaria-free world.

For the free pdf of this book please see attachement or download this book here.

Podcast: Multidose Priming and Delayed Boosting Improves PfSPZ Vaccine Efficacy

September 18, 2020 - 11:51 -- Malaria Minute

Malaria Minute, 18 September 2020
Multi-dose priming and delayed boosting improves PfSPZ protection against different strains of malaria, and registration opens for this year’s Molecular Parasitology Meeting.
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New from MESA: Volunteer as MESA Correspondent to report from the virtual ASTMH Annual Meeting

September 16, 2020 - 09:53 -- MESA Alliance

The Malaria Eradication Scientific Alliance (MESA) is seeking volunteers as MESA Correspondents to report from the virtual ASTMH Annual Meeting happening on November 15 - 19, 2020.

Malaria and COVID-19: country perspectives

September 10, 2020 - 11:31 -- Malaria World

How have country-based malaria experts adapted to the double challenge of malaria and COVID-19? What successes have they achieved, and where are the remaining gaps?  In a virtual forum on 3 September, 10 Ministry of Health representatives shared their experiences and reflections; you can watch their presentations below.

On 4 September, participants heard from senior political and health leaders from 2 regions that are heavily impacted by malaria; you will find below the presentations of WHO’s Regional Director for Africa, India’s Health Secretary and the Ugandan Minister of Health.

Podcast: Host-Directed Interventions Could Reduce Malaria Burden

September 1, 2020 - 13:01 -- Malaria Minute

Malaria Minute, 28 August 2020
Inhibiting human protein kinases, which are activated by the malaria parasite, could reduce the malaria burden, and researchers explore the use of AI in automating malaria diagnosis.
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Immunoglobulins and lactoferrrin against viral attacks

August 31, 2020 - 18:33 -- Pierre Lutgen

Pascal Gisenya, Pierre Lutgen

Mucosal surfaces represent a major interface between host and environment. They constitute the point of entry of most infectious pathogens, and are in contact with potentially injurious antigens present in the normal mucosal microflora and in ingested or inhaled substances.

MUCOSAL LININGS ARE RICH IN IMMUNOGLOBULINS

Older adults, Zinc deficiency, Artemisia and Corona

August 19, 2020 - 19:57 -- Pierre Lutgen

submitted by Pierre Lutgen, Jerome Munyangi and Mutaz Akkawi

Zinc (Zn) plays an essential role in many biological processes including immune response. Impaired Zn status promotes immune dysfunction, and it has been associated with enhanced chronic inflammation during aging. Zinc has a pivotal role in the entire immune system fostering resistance to infections by virus, fungi and bacteria. The immune system is strongly impaired by zinc deficiency, predominantly the cell-mediated response by T-lymphocytes.

Podcast: Peptide-Based PD1 Antagonist Stimulates T Cell Responses

August 15, 2020 - 14:05 -- Malaria Minute

Malaria Minute, 14 August 2020
A peptide derived from Bacillus bacteria stimulates the production of T cells prophylactically and therapeutically, and researchers explore the use of satellite imagery to assess the suitability of malaria vectors in different geographies.
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New from MESA: Malaria Consortium updates its research and implementation activities in MESA Track

August 12, 2020 - 18:02 -- MESA Alliance

Malaria Consortium’s work includes technical assistance, implementation and research activities. One of the main goals of the organisation is to identify innovative approaches for monitoring, evaluation and surveillance systems, and high-quality implementation research leading to evidence-based strategies for the control and eventual elimination of malaria. Browse MESA Track to discover their research efforts in more than 10 countries.

Podcast: New Insights Into Erythrocyte-Binding Plasmodium Protein

July 31, 2020 - 10:38 -- Malaria Minute

Malaria Minute, 31 August 2020
Scientists publish new insights into Plasmodium falciparum P2, and the IDDO launch an online tool to map the prevalence of substandard and falsified antimalarial drugs around the world.
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