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Accumulation of the Uncommon: OX513A Releases and Genome Introgression

September 23, 2019 - 13:00 -- Mark Benedict

A paper that appeared in Scientific Reports by Evans et al. (1)asked whether changes in the genotypes of target mosquito populations would occur due to introgression of released transgenic mosquito genomes. The paper in fact describes the introgression of released mosquito strain genome into wild populations of Aedes aegypti after releases of the OX513A strain developed by Oxitec and the paper has generated a lot of controversy. Is this a surprising finding or an entirely predictable outcome? Is it cause for alarm?

Podcast: Scientists in Burkina Faso Release Genetically Sterilised Mosquitoes

September 20, 2019 - 11:52 -- Malaria Minute

Malaria Minute, 20 September 2019

Scientists release genetically sterilised mosquitoes in Burkina Faso and the challenges of evaluating the efficacy of new drugs in malaria-endemic countries. Listen to this Podcast

Last week at MalariaWorld: Should we put a deadline for when the world will be free of malaria?

September 20, 2019 - 11:00 -- Ingeborg van Schayk

New MalariaWorld Poll

Should we put a deadline for when the world will be free of malaria?

What do you think about the current malaria eradication discussion. Should we put a deadline for when the world will be free of malaria? Yes - it will sustain momentum (Lancet commission report) or No - setting a target date is premature (SAG/WHO report).  Let us know!
Fill out the poll here


MalariaWorld and MESA will report from the 6th Annual PAMCA conference

Meet the MESA Correspondents
The upcoming conference of the Pan Africa Mosquito Control Association (PAMCA) will take place from 23-25 September, 2019 in Yaoundé, Cameroon. MalariaWorld, MESA and PAMCA will work together to provide you with an impression of the PAMCA conference presentations. The MESA Correspondents that will cover the 6th Annual PAMCA Conference are Joanna, Nathalie, Teresia and Trizah (from left to right). Read more


Events

Keystone Symposia: ePanel and live Q&A - Accelerate to Equal: Engaging Women in Vector Control
Date: October 1, 2019 | Time: 13:00 UTC (GMT) | 7AM MDT (USA)  |  16:00 EAT (Kenya)  |  20:00 WIB (Indonesia)
Read more

Global Excellence Research Symposium II “New Wine in old Bottles and Old Wine in new Bottles” - Past, present and future use of antimalarial and other drugs in the control of malaria: applications and dilemmas
Time: 16 October, 13:00 - 18 October, 12:00 ; Place: Holst Auditorium, Panum Institute, Blegdamsvej 3B, 2200 Copenhagen; Organizer: CMP, KU.
Participation in this symposium is free, but you will be expected to pay for and arrange your own accommodation. There is a limited capacity; first come, first served! Read more


This weeks Malaria Minute Podcast

Scientists in Burkina Faso Release Genetically Sterilised Mosquitoes
Scientists release genetically sterilised mosquitoes in Burkina Faso and the challenges of evaluating the efficacy of new drugs in malaria-endemic countries. Listen to this Podcast


Global Malaria News

Dams increase the risk of malaria. Here’s why
The Conversation, 17 September 2019
More rigorous impact prediction assessments must be done at the planning stages to determine the likely malaria impacts when considering new dams. Greater consideration must be given to the slopes of reservoir shores and the implications for malaria. Read more

Malaria vaccine launched in Kenya: Kenya joins Ghana and Malawi to roll out landmark vaccine in pilot introduction
WHO, 13 September 2019
The World Health Organization (WHO) congratulates the Government of Kenya for launching the world’s first malaria vaccine today in Homa Bay County, western Kenya. Read more

Genetically engineered mosquitoes out of control
GMWatch, 11 September 2019
According to a new scientific publication, genetically engineered mosquitoes produced by the biotech company Oxitec (Intrexon) have escaped human control after trials in Brazil. Read more

Read more global malaria news here.


Enjoy this week's MalariaWorld - the MW team

MalariaWorld and MESA join hands to report from the 6th Annual PAMCA conference

September 19, 2019 - 12:29 -- Malaria World

The upcoming conference of the Pan Africa Mosquito Control Association (PAMCA) will take place from 23-25 September, 2019 in Yaoundé, Cameroon. Like we did during the last MIM conference, MalariaWorld and the MESA Correspondent Program will work together to provide you with an impression of the PAMCA conference presentations.

The MESA Correspondent volunteers report on the latest in malaria research from conferences around the world. The synopses are shared online, enabling people who could not attend the meeting to read about the latest advances. The MESA Correspondents Program is a collaboration between MESA and the conference organizers.

Podcast: Eradicating Malaria by 2050 ‘Bold but Attainable’

September 13, 2019 - 14:13 -- Malaria Minute

Malaria Minute, 13 September 2019

Eradicating malaria by 2050 is a ‘bold but attainable goal’ according to The Lancet and ivermectin proves successful in reducing malaria transmission and killing P. falciparum parasites. Listen to this Podcast

Podcast: Biomarker Predicts Susceptibility to Malaria Fever

September 10, 2019 - 09:33 -- Malaria Minute

Malaria Minute, 6 September 2019

Scientists learn that a child’s immunological signature can predict whether they will develop malaria fever and the Wellcome Sanger Institute launch their Malaria Cell Atlas. Listen to this Podcast

Podcast: Malaria Will Not Be Eradicated in the Foreseeable Future

September 4, 2019 - 08:52 -- Malaria Minute

Malaria Minute, 30 August 2019

WHO announce that malaria will not be eradicated in the foreseeable future and a new study reveals drug-resistant P. falciparum parasites in every region of Africa. Listen to this Podcast

Podcast: British Doctor Celebrated on World Mosquito Day

September 4, 2019 - 08:48 -- Malaria Minute

Malaria Minute, 23 August 2019

World Mosquito Day celebrations take place, researchers culture malaria parasites similar to P. vivax in vitro and entomologists gather in London for the Ento ’19 scientific meeting. Listen to this Podcast

We are far from a malaria-free world: Q&A about malaria eradication with Pedro Alonso

August 28, 2019 - 15:18 -- Malaria World

Interview with Pedro Alonso, Director of the WHO Global Malaria Programme, following the publication of the report "Malaria eradication: benefits, future scenarios and feasibility" by the WHO Strategic Advisory Group on Malaria Eradication. This report concludes that with our current tools, we are far from a malaria-free world.

Size matters: Do ‘large cages’ for mosquito trials have any objectively meaningful dimensions?

August 26, 2019 - 14:25 -- Mark Benedict

Teams testing mosquitoes that are being considered for field release, their advisors, policy makers and donors often talk about ‘large cage trials’, but how large must a cage be for mosquito trials to qualify for that title? Is the proper metric its volume or stimulation of behavioral characteristics for a cage that provides the data we need? Perhaps the real value of large cage testing is neither of these but its independence.

Report: Malaria eradication: benefits, future scenarios and feasibility. Executive summary of the report of the WHO Strategic Advisory Group on Malaria Eradication

August 23, 2019 - 14:24 -- Malaria World

23 August 2019 | Report


After its 3-year study of trends and future projections for the factors and determinants that underpin malaria, the Strategic Advisory Group on Malaria Eradication (SAGme) reaffirms that eradication is a goal worth pursuing, likely to save millions of lives and billions of dollars. However, with our current tools, we are far from a malaria-free world.

Why malaria mosquitoes are still dancing in our bedrooms

August 19, 2019 - 22:10 -- Fredros Okumu

IN 30 SECONDS: Today, most malaria mosquitoes in Tanzania are resistant to multiple insecticides, and Anopheles funestus is the hardiest of them all. They are regularly observed surviving up to 10 times higher insecticide doses than other malaria vectors. Unfortunately, there are currently no more than three insecticides registered in Tanzania that can effectively kill the mosquitoes. And if we do not deploy these available chemicals cleverly, we will lose this battle too. So, what then must we do? Well, in addition to current practices such as ITNs and house-spraying, we must begin a more sustainable program for improved housing and environmental management so that we may make our communities everlastingly free of the dangerous Anopheles. We must also continue strengthening our health systems to identify and treat new malaria cases. And we must expand access to health education in schools and households. Without these improvements, the deadly predators will most certainly continue dancing in our bedrooms.

Volunteer as a MESA Correspondent to report from PAMCA

August 14, 2019 - 21:06 -- MESA Alliance

The Malaria Eradication Scientific Alliance (MESA) is seeking three volunteer MESA Correspondents to report from the Pan-African Mosquito Control Association (PAMCA) annual conference in Yaounde, Cameroon, 23-25 September 2019.

Podcast: Studying the Genes That Cause Insecticide Resistance

August 7, 2019 - 14:42 -- Malaria Minute

Malaria Minute, 2 August 2019

Researchers investigate the genes that cause insecticide resistance among malaria-carrying mosquitoes, The Global Fund launch their ‘Step Up The Fight’ awareness campaign and Alok Sharma is named as UK Secretary of State for International Development. Listen to this Podcast

No toxicity detected for Artemisia annua or afra

August 5, 2019 - 19:06 -- Pierre Lutgen

Artemisias are used since millenaries and never any toxic effect was noticed. If there was one it would have been highlighted by Bigparma because the plant competes with their pills.

The WHO guidelines state that, if the herbal product has been traditionally used without demonstrated harm, no specific restrictive action should be undertaken. In this case WHO maintains the position that there is no requirement for pre-clinical toxicity testing. Pre-clinical toxicity testing is only required for new medicinal herbal products which contain herbs of no traditional history of use.

Podcast: Drug-Resistant Malaria Parasites Spread to SE Asia

August 1, 2019 - 02:14 -- Malaria Minute

Malaria Minute, 26 July 2019

Drug-resistant P. falciparum spread to South East Asia, researchers at LSTM uncover the mode of action of primaquine and the International Health journal will become open-access in 2020. Listen to this Podcast

Podcast: Understanding Human Behaviour Key To Malaria Elimination

July 22, 2019 - 13:14 -- Malaria Minute

Malaria Minute, 19 July 2019

Understanding human behaviour at night could reduce malaria transmission, study shows how the mosquito immune system combats malaria parasites and a researcher uncovers new insights into mosquito feeding behaviours. Listen to this Podcast

Podcast: No Evidence of Malaria Rebound in Extended Phase 3 RTS,S Clinical Trial

July 15, 2019 - 03:13 -- Malaria Minute

Malaria Minute, 12 July 2019

The results of an extended Phase 3 RTS,S clinical trial are published in The Lancet, and researchers develop a high-tech mosquito net that monitors usage. Listen to this Podcast

New from MESA: MESA Correspondents bring you cutting-edge coverage from the 7th International Conference on Plasmodium vivax Research - Day 3

July 1, 2019 - 19:47 -- MESA Alliance

Day 3: Friday, 28th June

Wrapping up the 7th International Conference on Plasmodium vivax Research, day three focused on the topics of P. vivax drugs and approaches for P. vivax elimination.

New from MESA: MESA Correspondents bring you cutting-edge coverage from the 7th International Conference on Plasmodium vivax Research - Day 2

July 1, 2019 - 10:57 -- MESA Alliance

Day 2: Thursday, 27th June

The main focus of the presentations on day two of the 7th International Conference on Plasmodium vivax Research was on laboratory exploration of P. vivax biological characteristics, parasite development stages and host-parasite interaction. There was a lively poster session during the lunch period and a conference dinner at the magnificent Musée d’Orsay.

Podcast: 7th International Conference on Plasmodium vivax Research

July 1, 2019 - 10:34 -- Malaria Minute

Malaria Minute, 28 June 2019

Scientists gather in Paris for the 7th International Conference on Plasmodium vivax Research, high-resolution maps chart P. falciparum and P. vivax prevalence over seventeen years and Brian Gitta is named a laureate for developing a new method of malaria diagnosis. Listen to this Podcast

RBM Partnership To End Malaria Annual Report 2018

June 26, 2019 - 20:02 -- Malaria World

2018 was the first year of the RBM Partnership to End Malaria’s 2018–2020 Strategic Plan (see page 7), which aims to use the partnership to boost political commitment, regional cooperation and malaria financing. The Partnership, through consultations with partners and malaria-endemic countries, launched new initiatives in support of global efforts to end malaria. 

Download the RBM Partnership To End Malaria Annual Report 2018 here

New from MESA: Malaria, collaborating to succeed

June 26, 2019 - 12:51 -- MESA Alliance

Mary Mael and Maria Tusell*

Participants in the Science of Eradication: Malaria course shared a sense of optimism and agreed on the need for leadership and data-driven decision-making in the fight against this disease

“Collaboration” was probably the word most heard when asking the participants of the 8th edition of the Science of Eradication: Malaria course how they thought the fight against malaria could be improved. Even though progress has stalled, as highlighted by the head of the Global Malaria Programme, Pedro Alonso, in the opening lecture, participants left Barcelona with a shared feeling of optimism and a perception that with commitment, a multidisciplinary approach to the disease and data-driven decisions; malaria control, elimination and eradication are indeed achievable goals.

Podcast: WHO Report Tracks Malaria Elimination Progress

June 26, 2019 - 11:01 -- Malaria Minute

Malaria Minute, 21 June 2019

New WHO report tracks the progress of 21 countries in eradicating malaria, the BBC investigate the sale of government drugs in Uganda and Professor Tu YouYou offers her recommendations to prevent artemisinin resistance. Listen to this Podcast

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