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Ultrapurity: a fatal error in pharmacognosy

June 11, 2017 - 16:55 -- Pierre Lutgen

It is common belief and a dogma of the Western school medicine that valid results with the extracts of natural products can only be obtained if individual constituents are isolated and purified to the highest grade. This entails that most, if not all, scientific papers describing research in this field are based on monotherapies with ultrapure products.

Congratulations to Austin Burt!

May 25, 2017 - 04:52 -- Ingeborg van Schayk

Professor Austin Burt has been awarded a President's Medal for his work engaging the public in malaria-control projects across sub-Saharan Africa.

The accolade is given out as part of the College’s annual President's Awards for Excellence in Societal Engagement. These awards celebrate staff, students and community partners who have gone the extra mile to bring the College’s work to the wider public. Awardees judged to have made particularly exceptional contributions are selected to receive the President’s Medal for Excellence in Societal Engagement.

"Now, more than ever, universities should be in and of the world. We cannot afford to retreat to ivory towers"
– Professor Maggie Dallman, Associate Provost (Academic Partnerships)

The Societal Engagement awards form part of the President’s Awards for Excellence programme, with similar prizes also being given for research and education.

Read the full article "Imperial academic puts community at the heart of malaria elimination project" by Deborah Evanson - Imperial College London, here.

Last week at MalariaWorld: Nigeria Prize for Science 2017

May 12, 2017 - 14:15 -- Ingeborg van Schayk

The Nigeria Prize for Science: Innovations in Malaria Control
The theme for the 2017 Nigeria Prize for Science is Innovations in Malaria Control. This competition is organized by Nigeria LNG Limited and is in line with its vision of helping to build a better Nigeria. Read the announcement here.

Antimalarial candidate holds promise as a single dose
A new antimalarial candidate could pave the way for a single-dose treatment that boots malaria eradication when used in combination with other preventative measures. Read the SciDev.Net article "Antimalarial candidate holds promise as a single dose" here and the article "Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase" here.

Enjoy this week's MalariaWorld - the MW team

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SciDev.Net: Antimalarial candidate holds promise as a single dose

May 12, 2017 - 12:57 -- Ingeborg van Schayk
  • A potential antimalarial was trialled in animals as a single dose
  • They found that it could block all life cycle stages of mosquitoes
  • An expert says the drug could advance malaria control if it reaches the market

[CAPE TOWN] A new antimalarial candidate could pave the way for a single-dose treatment that boots malaria eradication when used in combination with other preventative measures.

Artemisia guérit en RDC 18 cas de malaria sévère quand les ACT ont échoué.

April 29, 2017 - 17:56 -- Pierre Lutgen

This is a translation of  the Worcester Polytechnic Institute press release 

Worcester, Mass. – April 24, 2017 – Quand les remèdes prescrits n’arrivaient plus à guérir 18 impaludés en situation désespérée, leur médecin traitant dans une clinique du Congo, en se basant sur les procedures du “compassionate use” de l’EMA, a eu recours à un mécicament non encore officiellement autorisé et consistant en comprimés de feuilles séchées de la plante Artemisia annua (désignés sous DLA).

New from MESA: Malaria researchers share cutting-edge science, on film

April 26, 2017 - 14:23 -- MESA Alliance

In February 2017, malaria experts from around the world gathered in Kampala, Uganda  to attend "Malaria: From Innovation to Eradication", a conference organized by Keystone Symposia in collaboration with MESA.  Eight scientists shared their cutting edge research with MESA, on film. 

New from MESA: ‘Top 5 Picks!’ – Researchers choose their favourite malaria articles from the past year

April 26, 2017 - 13:59 -- MESA Alliance

“As a researcher working in a country that has decided to take on the challenge of eliminating malaria, the knowledge in the paper is enriching”. This is how Sandra Chishimba chose her ‘Top Pick’ article for World Malaria Day 2017.  MESA (Malaria Eradication Scientific Alliance) asked five experts what recent paper has helped them in their effort to outsmart malaria. The papers had to be open access, authored by another group, and published in the last 12 months.

Prevent malaria - save lives: WHO push for prevention on World Malaria Day, 25th April

April 25, 2017 - 11:18 -- Ingeborg van Schayk

24 APRIL 2017 | GENEVA, NAIROBI - At an event on the eve of World Malaria Day in Nairobi, WHO called today for accelerated scale-up of efforts to prevent malaria and save lives.

In sub-Saharan Africa, which shoulders 90% of the global malaria burden, more than 663 million cases have been averted since 2001. Insecticide-treated nets have had the greatest impact, accounting for an estimated 69% of cases prevented through control tools.

The 2017 malaria avalanche

April 2, 2017 - 19:29 -- Pierre Lutgen

Bigpharma-WHO-Gates desperately try to ignore peer reviewed scientific papers documenting the spread of ACT resistance in at least 12 African countries (see “Artemisinin resistance In Africa” www.malariaworld.org).

Several medical teams in Africa have demonstrated in randomized, double blind clinical trials that Artemisia infusions are powerful in therapy and prophylaxis (see “Breaking news from clinical trials with Artemisia plants” www.malariaworld.org).

Village planning for intrinsic prevention of malaria transmission

March 25, 2017 - 19:51 -- William Jobin

The Eltahir group at MIT has recently published a pioneering study which makes it possible to plan resettlement and new villages in ways which will permanently minimize malaria transmission, because of ecological design. This is especially valuable for engineers planning resettlement communities related to large reservoirs and irrigation systems.

Such safe designs reduce the need for the ephemeral methods based on drugs, bednets and insecticides.

The report is:

The antimalarial davanone in several Artemisia species

March 11, 2017 - 20:03 -- Pierre Lutgen

In Mexico eight species of Artemisia have been described and among them just Artemisia ludoviciana has been empirically used in the treatment of intermittent fever (malaria). To know whether this Mexican Artemisia had antimalarial activity several in vivo experiments were performed, on mice infected by Plasmodium yoelii yoelii, in a four-day test scheme. The results of the in vivo experiments showed that the parasite reproduction was inhibited up to 98.6% at the fifth day.

Global health experts define malaria work packages

March 3, 2017 - 13:54 -- Ingeborg van Schayk

28 February 2017, WHO

Members of the WHO Strategic Advisory Group (SAG) on malaria eradication recently convened in Geneva to review and define a set of work streams for the next 2-year period. The proposed scope of work is cross-cutting and spans a breadth of domains: biological, technical, financial, socio-economic, political and environmental.

Exciting new science and big challenges for the next generation of malaria scientists

February 24, 2017 - 11:29 -- MESA Alliance

Keystone Symposia malaria meeting in Kampala - Day 5

Thursday, 23 February 2017

This morning was full of exciting science on the malaria parasite and its interaction with human and mosquito hosts.  A common message from the presenters was the dynamic nature of parasite populations.  Today’s parasites are adapting to evolutionary pressure and will not be the same in the future.  As countries reach elimination, tools and strategies need to adapt as well.

UN SECOND MASSACRE AU BURUNDI

February 6, 2017 - 13:28 -- Pierre Lutgen

 

received from Emile Schmitz, Athus

abstract

      Caused not by racial or religious conflict, but by greed.

      Every year WHO claims that the battle against malaria is won and that the number of malaria infections has been halved. Unfortunately, in several countries the disease is exploding. In Burundi the number of infections has increased from 4 716 152 in 2014 to 7 813 958 in 2016.

      A recent mission of WHO to this country had to confess a complete failure of LLINs and ACTs.

 

Very efficient prophylaxis with Artemisia annua: another Congolese breakthrough

January 26, 2017 - 20:11 -- Pierre Lutgen

 4 years ago, a heated debate concerning malaria prophylaxis had been triggered on www.malariaworld.org. It concerned the very promising results obtained by Dr Patrick Ogwang, with an herbal product called Artavol, he had developed with the Ministry of Health in Uganda. Peer reviewed papers and press releases are easily found on internet.

What will become of the US Malaria Initiative now?

January 25, 2017 - 13:51 -- William Jobin
Tags: 

Since the Trump administration came into office, there are real uncertainties about the long-standing US Presidential Malaria Initiaitive (the PMI), which I helped start in 2005. Firstly, the Administrator Tim Ziemer, who has given the Initiative real stability for 8 years, has resigned. Secondly it appears that the very conservative Newt Gingrich will take over USAID which funds the PMI within the US State Department. Gingrich is opposed to USAID and might dismantle it. Fortunately the new US Secty of State Rex Tillerson has gone on record as favoring the health programs of USAID.

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