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Podcast: Chloroquine Considered as Potential Treatment for COVID-19

March 27, 2020 - 16:48 -- Malaria Minute

Malaria Minute, 27 March 2020

Scientists evaluate chloroquine as a potential treatment for the coronavirus and, as it continues to spread around the world, a report in The Lancet stresses the need for preparedness in malaria-endemic regions.

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Last week at MalariaWorld: Personal message

March 26, 2020 - 17:47 -- Ingeborg van Schayk

Personal Message

We are all in an unprecedented and unpredictable situation. For those of you who are effortlessly working in the health sector to take care of patients, family and friends, we so much respect and appreciate the work you are doing.

These are uncertain times. We worry about the health of our kids, our family, ourselves, our friends, our neighbours and colleagues. Whilst focussing on controlling the corona virus we continue to fight against malaria as well.

We wish you all the strength you need to stay healthy and stay safe.

Please take care of one another.

Warm regards on behalf of the entire MalariaWorld team,


 


Message from WHO

WHO urges countries to ensure the continuity of malaria services in the context of the COVID-19 pandemic
The COVID-19 pandemic is testing the resilience of robust health systems around the world. Recognizing the heavy toll that malaria exacts on vulnerable populations in sub-Saharan Africa, as well as the region’s fragile health infrastructure, WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria... Read more

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New from MESA

ASTMH 2019 Recap in the MESA Resouce Hub: Routine Data for Decision-Making: Driving Progress in Malaria Control
Watch the presentations from this symposium, in which experts from three different African countries (Mozambique, Tanzania and Zambia) highlighted innovative initiatives across diverse setting to use routine data for decision-making... Watch these publications
 


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WHO urges countries to ensure the continuity of malaria services in the context of the COVID-19 pandemic

March 25, 2020 - 16:30 -- Malaria World

Safety of front-line health workers a primary concern

The COVID-19 pandemic is testing the resilience of robust health systems around the world. Recognizing the heavy toll that malaria exacts on vulnerable populations in sub-Saharan Africa, as well as the region’s fragile health infrastructure, WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria.

New from MESA: ASTMH 2019 Recap in the MESA Resource Hub: Routine Data for Decision-Making: Driving Progress in Malaria Control

March 25, 2020 - 15:22 -- MESA Alliance

Watch the presentations from this symposium, in which experts from three different African countries (Mozambique, Tanzania and Zambia) highlighted innovative initiatives across diverse setting to use routine data for decision-making.

Podcast: PIMMS43 Enables Malaria Parasite to Evade Mosquito Immune System

March 20, 2020 - 17:07 -- Malaria Minute

Malaria Minute, 20 March 2020

A protein called PIMMS43 enables the malaria parasite to evade the mosquito’s immune system and scientists describe a highly conserved protein in the malaria parasite that is essential for the invasion of red blood cells.

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Podcast: Demand for Coffee Has a Direct Link to Malaria Risk

March 14, 2020 - 17:37 -- Malaria Minute

Malaria Minute, 14 March 2020

The global supply chain linked to deforestation leads to an increase in malaria prevalence and scientists identify the mechanism of action of clemastine, an antihistamine that inhibits multiple stages of the malaria parasite’s lifecycle.

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New from MESA: ASTMH 2019 Recap in the MESA Resouce Hub: Learning from experience to optimize chemoprevention strategies for malaria

March 10, 2020 - 16:35 -- MESA Alliance

Watch the presentations from this MESA-organized symposium, which brought together a group of experts to address the latest advances in malaria chemoprevention and discuss the impact and challenges faced when translating and scaling up from the trials to the field.

Podcast: Researchers Target Plasmepsin as Avenue for Potential New Therapies

March 7, 2020 - 17:33 -- Malaria Minute

Malaria Minute, 7 March 2020

Researchers target Plasmepsin proteases as resistance to ACT grows, and the process by which the malaria parasite suppresses the immune system is detailed by scientists.

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Podcast: Scientists Convene for MAM2020 in Australia

February 29, 2020 - 14:26 -- Malaria Minute

Malaria Minute, 28 February 2020

The Molecular Approaches to Malaria Conference takes place in Australia, and a study into the long-term side effects of antimalarials could not identify any sufficient evidence of association between malaria prophylaxis and adverse health effects.

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Artemisia afra completely inhibits transmission of gametocytes

February 27, 2020 - 19:35 -- Pierre Lutgen

Gametocytes are loaded with hemozoin resulting from hemoglobulin consumption. Their voracious need of this food may explain why they hide in the bone marrow where they find a large supply of young red blood cells generated by erythropoiesis. Malaria leads to hemolysis and anemia, often severe, and this triggers and amplifies erythropoiesis.  Over the years it became evident that not only intravenous artesunate often causes hemolysis, but also ACT therapy.

New from MESA: ASTMH 2019 Recap in the MESA Resouce Hub: Emerging evidence in school-based malaria interventions from Uganda, Rwanda and Mali

February 27, 2020 - 17:45 -- MESA Alliance

Watch the presentations from ASTMH 2019's symposium entitled "Interventions to decrease the burden of malaria in school-aged children", chaired by Dr Julie Gutman and Dr Miriam Laufer. 

Podcast: Condensin Proteins Essential for Malaria Proliferation and Transmission

February 21, 2020 - 17:57 -- Malaria Minute

Malaria Minute, 21 February 2020

Scientists identify two proteins that are essential for the malaria parasite’s genetic malleability, and the substance responsible for ‘rosette’ formation in human red blood cells is identified.

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New from MESA: Volunteer as a MESA Correspondent to report from the "Genomic Epidemiology of Malaria" Conference

February 18, 2020 - 20:06 -- MESA Alliance

The Malaria Eradication Scientific Alliance (MESA) is seeking three volunteers as MESA Correspondents to report from the "Genomic Epidemiology of Malaria" Conference in the Wellcome Genome Campus, UK, June 08 - 10, 2020.

Podcast: EphA2 Protein Mediates Critical Stage of Cerebral Malaria

February 14, 2020 - 17:54 -- Malaria Minute

Malaria Minute, 14 February 2020

Scientists find that the EphA2 protein mediates a critical stage of cerebral malaria and data scientists construct a statistical modelling framework of malaria seasonality in Madagascar.

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Why are antimalarials bitter?

February 7, 2020 - 16:35 -- Pierre Lutgen

From prehistoric times man has looked to wild and domestic animals for sources of herbal remedies. Both folklore and living examples provide accounts of how medicinal plants were obtained by observing the behaviour of animals. Animals too learn about the details of self-medication by watching each other. To date, perhaps the most striking scientific studies of animal self-medication have been made on the African great apes.

RTS,S vaccine: an African medical doctor raises the alarm.

February 1, 2020 - 14:57 -- Pierre Lutgen
Tags: 

 

This document was submitted to us by Jerôme Munyangi, who run the successful large scale clinical trials against malaria with Artemisia plants in Maniema, RDC.

        (Jerome Munyangi et al., Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine(ASAQ) in treating Plasmodium falciparum malaria in a large scale, doubleblind, randomized clinical trialPhytomedicine, 2019, 57, 49-56)

Our association IFBV-BELHERB shares his concern for his African sisters and brothers. They should not be used as guinea pigs by Bigpharma.

 

Podcast: Optimising Vaccine Efficacy Using Tobacco Mosaic Virus

January 31, 2020 - 14:27 -- Malaria Minute

Malaria Minute, 31 January 2020

Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.

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Podcast: Optimising Vaccine Efficacy Using Tobacco Mosaic Virus

January 31, 2020 - 14:27 -- Malaria Minute

Malaria Minute, 31 January 2020

Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.

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Podcast: Antibodies Marker of Exposure to Malaria in Pregnant Women

January 24, 2020 - 14:18 -- Malaria Minute

Malaria Minute, 24 January 2020

Malaria antibodies in pregnant women may be a marker of exposure, not protection, from malaria and a combination of antimalarial drugs is less efficacious than if used in tandem.

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Podcast: Single-Cell Genome Processing Demonstrates Origin of Complex Malaria

January 17, 2020 - 10:13 -- Malaria Minute

Malaria Minute, 17 January 2020

Single-cell genome processing yields surprising results about the origin of complex malaria and study finds that the management of malaria in children at schools is ineffective.

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Podcast: DNA Methylation Inhibitor Molecules Kill Plasmodium Parasites

January 3, 2020 - 18:12 -- Malaria Minute

Malaria Minute, 3 January 2020

Researchers from the Pasteur Institute discover molecules that can kill the malaria parasite and researchers from LSTM identify a resistance mechanism for insecticides used on bed nets.

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Artemisia afra and blood pressure

December 17, 2019 - 20:03 -- Pierre Lutgen

 

Another important property of Artemisia plants. Might help us to better understand the high efficacy against tropical diseases.  Just published  in PPIJ! See pdf attached

 

And as Artemisia afra is endemic in so many African countries and used since generations as traditional medicine against malaria no further pre-clinical trials are required as per WHO/EDM/TRM/2000.1    

This traditional use is recognized by  WHO in the October 2019 statement WHO-CDS-GMP-2019.14

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