The University of Malaya hosted the "Current Tools to Combat Malaria - with Special Focus on Plasmodium knowlesi" workshop on March 4 - 8, 2019, which had 20 participants from eight different countries. Dr Lucas Low Van Lun covered this intensive week of lectures and practical sessions and reported the daily lessons learnt in a series of reports posted in the Resource Hub.
WHO guidelines for malaria vector control
The Guidelines for malaria vector control provide a “one-stop shop” for all countries and partners working to implement effective malaria vector control measures. They cover the 2 core malaria vector control interventions – ITNs and IRS – as well as supplementary interventions, namely chemical and biological larvicides, and personal protection measures, such as the use of topical repellents. Read more
Job opportunities
Reminder: Project Manager Malaria at ISGlobal
ISGlobal is looking for an experienced Project Manager for the Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA) project. Deadline for applications is 15 April 2019. Read more
Reminder: Clinical Trial Manager Malaria at ISGlobal
ISGlobal is looking for an experienced Clinical Trial Manager for the the Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA) project. Read more
Global Malaria News
Mass drug administration against malaria seen effective
SciDev.Net, 4 March 2019
Medical researchers say that mass administration of combination drugs can stop the transmission of malaria caused by the Plasmodium falciparum parasite and reduce its prevalence in South-East Asian countries, where resistance of the disease to artemisinin, the standard drug, has hampered elimination efforts. Read more
A quick path to antimalarial resistance
ScienceDaily, 4 March 2019
Resistance to antimalarial drugs is thought to result mainly from changes in the parasite's genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new study. This is of concern because resistance acquired at the epigenetic level can arise quickly, even during the course of a single infection. Read more
Earlier emergence of malaria in Africa
ScienceDaily, 28 February 2019
Malaria is one of the leading causes of death by an infectious agent, the Plasmodium falciparum parasite. In research on malaria, the genetic mutation that causes sickle cell anemia (also known as drepanocytosis), a chronic disease that is often fatal in children under five, caught the attention of the scientific community very early on because it also provides protection against malaria. Read more
Read more global malaria news here.
Enjoy this week's MalariaWorld - the MW team
The Guidelines for malaria vector control provide a “one-stop shop” for all countries and partners working to implement effective malaria vector control measures. They cover the 2 core malaria vector control interventions – ITNs and IRS – as well as supplementary interventions, namely chemical and biological larvicides, and personal protection measures, such as the use of topical repellents.
This report has been prepared to provide a comprehensive account of the history of malaria and its control in the Islamic Republic of Iran for specialists and lay readers alike. It is based on published and unpublished reports, especially from the Ministry of Health and Medical Education, Tehran, and from the World Health Organization. The main findings are summarized below.
WHO is undertaking a consultative process to solicit inputs into a prioritization framework for the research and development (R&D) of malaria health products. A draft report “Analysis of Malaria R&D Priorities” identifies five key challenges that represent threats or barriers to achieving the WHO Global Technical Strategy for Malaria 2016–2030 goals. This early copy of the report is being shared at a time when WHO is exploring how best to guide and support the development of priority solutions to meet public health needs.
WHO welcomes feedback on this draft report until 28 February 2019, including the correction of errors or omissions, updates to product development pipelines, and perspectives on the approach to prioritization.
FRANCE 24 brings you an in-depth investigation into the debate between those for and against this natural anti-malaria remedy, which appears as a threat to large pharmaceutical laboratories.
MESA co-hosting a critical global gathering in response to the latest disease reality and future innovation and financing needs
The MESA Alliance is set to co-host an invite-only scientific symposium entitled, “Innovate for Collective Impact to End Malaria”, on Friday, January 11, 2019, at the National Academy of Sciences in Washington, DC, USA. Its core objective is to frame a response to the 2018 World Malaria Report and to develop innovative approaches to collectively bridge critical issues in malaria eradication spanning research, financing, and implementation.
We are proud to inform you that MalariaWorld's Bart Knols has won the Marc Cornelissen Brightlands Award 2018 for his work in the fight against malaria.
Malaria is on the rise in more than 13 countries. And that is very scary!
This year's report shows that after an unprecedented period of success in global malaria control, progress has stalled. Data from 2015–2017 highlight that no significant progress in reducing global malaria cases was made in this period. There were an estimated 219 million cases and 435 000 related deaths in 2017.
The World malaria report 2018 draws on data from 91 countries and areas with ongoing malaria transmission. The information is supplemented by data from national household surveys and databases held by other organizations.
The most promising or the most frightening experiment in the fight against malaria: should or shouldn’t we use genetically modified mosquitoes to combat malaria?
TEXAS BIOMEDICAL RESEARCH INSTITUTE - PUBLIC RELEASE: 17-OCT-2018
More than 150 people have died from Ebola virus disease in 2018
San Antonio, Texas (October 17, 2018) -- Ebola virus is a continuing threat in Central and West Africa, with an outbreak currently taking place in the Democratic Republic of Congo. The disease kills up to 90% of the people who get infected, and more than 150 people have died from Ebola so far this year. The factors that determine who is susceptible to Ebola infection and who is not are still a mystery.
Silas Majambere, Mosquito Consulting
This repository comprises a carefully selected set of more than 190,000 bibliographic records covering all aspects of research on malaria.
The French periodical PARIS MATCH published an extensive document on the fight against malaria with Artemisia annua and Artemisia afra. And the dubious role WHO plays.
https://www.parismatch.com/Actu/Sante/Artemisia-et-paludisme-la-sante-entre-les-mains-des-Africains-1577250
Progress in malaria elimination across the Asia-Pacific is at critical cross-roads, threatened by the spread of multidrug resistant falciparum malaria and continued transmission among marginalized and mobile populations living and working in conditions beyond the reach of traditional malaria control interventions.
Dear colleagues,
As you probably do, I eagerly check MalariaWorld almost every day, and when I have something to contribute, post a blog or comment. But I am disappointed by the lack of responses to my contributions, or to those from all of you. How can we improve this?
Since almost 10,000 people are connected thru MalariaWorld, we might make real progress if we can all contribute. I want to end malaria sooner, not later. Do you agree?
Bill Jobin
Amiodarone which is used to control irregular heartbeat also has a protective effect in malaria. It triggers eryptosis and the clearance of malaria infected erythrocytes. In Plasmodium berghei infected mice amiodarone injections increased the survival. It is interesting to note that amiodarone is also active against other tropical diseases like Chagas or Leishmaniasis, both in vitro and in vivo, probably by disrupting the parasites' Ca(2+) homeostasis,
It is valuable and refreshing to see contributions to strategies for malaria suppression in Africa from other disciplines, such as economics. Killeen and Reed pointed out that the portfolio effect cushions mosquito populations and malaria transmission against vector control interventions.(Killeen GF, Reed TE. Malar J. 2018 Aug 10;17(1):291. doi: 10.1186/s12936-018-2441-z.) Thus it must be considered when planning a strategy for Africa.
Vaccines blocking the invasion of malaria sporozoites failed so far, after 30 years of efforts, millions spent, and disastrous human clinical trials. The efforts and the millions are now focused on vaccines blocking transmission by gametocytes. The results are not yet encouraging but the updated Malaria Vaccine Technology Roadmap foresees that there will be a TBV vaccine available in 2030. The update was necessary as the program launched by WHO in 2000 ( TDR/RBM/MAL/VAC/2000.1) has not yet progressed very far.
Edited by Sylvie Manguin and Dr Vas Dev
Published: July 18th 2018
DOI: 10.5772/intechopen.69750
ISBN: 978-1-78923-551-7
Print ISBN: 978-1-78923-550-0
Click here to read more about this Open access peer-reviewed Edited volume
In 2001 WHO posted a statement on their home page, without signatures, without references: « Due to the instability of artemisinin in raw materials of Artemisia annua L, the leaves need to be stored in cool conditions — preferably below 20°C. Most malaria endemic countries have warm climates and people generally lack access to refrigeration, so it is difficult for patients to keep artemisinin-containing tea bags under 20°C in their homes” A statement not substantiated by scientific papers. Cui bono?
Our associations immediately gathered available data which prove the contrary
“To end malaria there
is need for vision,
commitment and
people to lead that
vision as seen when
the first person landed
on the moon.”
Don't miss out! Last chance to register!
Join us from 1-5th July 2018 in Melbourne, Australia for this unique multi-sector Congress.
