Malaria Minute, 27 March 2020
Scientists evaluate chloroquine as a potential treatment for the coronavirus and, as it continues to spread around the world, a report in The Lancet stresses the need for preparedness in malaria-endemic regions.
Personal Message
We are all in an unprecedented and unpredictable situation. For those of you who are effortlessly working in the health sector to take care of patients, family and friends, we so much respect and appreciate the work you are doing.
These are uncertain times. We worry about the health of our kids, our family, ourselves, our friends, our neighbours and colleagues. Whilst focussing on controlling the corona virus we continue to fight against malaria as well.
We wish you all the strength you need to stay healthy and stay safe.
Please take care of one another.
Warm regards on behalf of the entire MalariaWorld team,
Message from WHO
WHO urges countries to ensure the continuity of malaria services in the context of the COVID-19 pandemic
The COVID-19 pandemic is testing the resilience of robust health systems around the world. Recognizing the heavy toll that malaria exacts on vulnerable populations in sub-Saharan Africa, as well as the region’s fragile health infrastructure, WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria... Read more
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New from MESA
ASTMH 2019 Recap in the MESA Resouce Hub: Routine Data for Decision-Making: Driving Progress in Malaria Control
Watch the presentations from this symposium, in which experts from three different African countries (Mozambique, Tanzania and Zambia) highlighted innovative initiatives across diverse setting to use routine data for decision-making... Watch these publications
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Safety of front-line health workers a primary concern
The COVID-19 pandemic is testing the resilience of robust health systems around the world. Recognizing the heavy toll that malaria exacts on vulnerable populations in sub-Saharan Africa, as well as the region’s fragile health infrastructure, WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria.
Watch the presentations from this symposium, in which experts from three different African countries (Mozambique, Tanzania and Zambia) highlighted innovative initiatives across diverse setting to use routine data for decision-making.
Malaria Minute, 20 March 2020
A protein called PIMMS43 enables the malaria parasite to evade the mosquito’s immune system and scientists describe a highly conserved protein in the malaria parasite that is essential for the invasion of red blood cells.
Malaria Minute, 14 March 2020
The global supply chain linked to deforestation leads to an increase in malaria prevalence and scientists identify the mechanism of action of clemastine, an antihistamine that inhibits multiple stages of the malaria parasite’s lifecycle.
Watch the presentations from this MESA-organized symposium, which brought together a group of experts to address the latest advances in malaria chemoprevention and discuss the impact and challenges faced when translating and scaling up from the trials to the field.
Malaria Minute, 7 March 2020
Researchers target Plasmepsin proteases as resistance to ACT grows, and the process by which the malaria parasite suppresses the immune system is detailed by scientists.
Malaria Minute, 28 February 2020
The Molecular Approaches to Malaria Conference takes place in Australia, and a study into the long-term side effects of antimalarials could not identify any sufficient evidence of association between malaria prophylaxis and adverse health effects.
Gametocytes are loaded with hemozoin resulting from hemoglobulin consumption. Their voracious need of this food may explain why they hide in the bone marrow where they find a large supply of young red blood cells generated by erythropoiesis. Malaria leads to hemolysis and anemia, often severe, and this triggers and amplifies erythropoiesis. Over the years it became evident that not only intravenous artesunate often causes hemolysis, but also ACT therapy.
BBC Radio Forum programme, broadcasted on 20 February 2020
How humans have tried to wage war against the mosquito for thousands of years - and who's winning the battle.
Watch the presentations from ASTMH 2019's symposium entitled "Interventions to decrease the burden of malaria in school-aged children", chaired by Dr Julie Gutman and Dr Miriam Laufer.
Malaria Minute, 21 February 2020
Scientists identify two proteins that are essential for the malaria parasite’s genetic malleability, and the substance responsible for ‘rosette’ formation in human red blood cells is identified.
The Malaria Eradication Scientific Alliance (MESA) is seeking three volunteers as MESA Correspondents to report from the "Genomic Epidemiology of Malaria" Conference in the Wellcome Genome Campus, UK, June 08 - 10, 2020.
Malaria Minute, 14 February 2020
Scientists find that the EphA2 protein mediates a critical stage of cerebral malaria and data scientists construct a statistical modelling framework of malaria seasonality in Madagascar.
Malaria Minute, 7 February 2020
Scientists identify the process by which the malaria parasite imports sugar, a potential target for inhibiting parasitic development.
From prehistoric times man has looked to wild and domestic animals for sources of herbal remedies. Both folklore and living examples provide accounts of how medicinal plants were obtained by observing the behaviour of animals. Animals too learn about the details of self-medication by watching each other. To date, perhaps the most striking scientific studies of animal self-medication have been made on the African great apes.
This document was submitted to us by Jerôme Munyangi, who run the successful large scale clinical trials against malaria with Artemisia plants in Maniema, RDC.
(Jerome Munyangi et al., Artemisia annua and Artemisia afra tea infusions vs. artesunate-amodiaquine(ASAQ) in treating Plasmodium falciparum malaria in a large scale, doubleblind, randomized clinical trialPhytomedicine, 2019, 57, 49-56)
Our association IFBV-BELHERB shares his concern for his African sisters and brothers. They should not be used as guinea pigs by Bigpharma.
Malaria Minute, 31 January 2020
Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.
Malaria Minute, 31 January 2020
Use of the tobacco mosaic virus platform to administer malaria antigens induces high and durable efficacy in macaques and individuals with an African-centric genetic variation may have an improved response to malaria.
Malaria Minute, 24 January 2020
Malaria antibodies in pregnant women may be a marker of exposure, not protection, from malaria and a combination of antimalarial drugs is less efficacious than if used in tandem.
Malaria Minute, 17 January 2020
Single-cell genome processing yields surprising results about the origin of complex malaria and study finds that the management of malaria in children at schools is ineffective.
The Malaria Eradication Scientific Alliance (MESA) is seeking three volunteers as MESA Correspondents to report from the EMBL Conference "Biology and Pathology of the Malaria Parasite" in Heidelberg, Germany, May 18 - 20, 2020.
WHO forecasts an alarming increase of diabetes in Africa, from 7 020 000 cases in 2000 to18 234 000 cases in 2030, with a high death toll if no efficient and affordable cure is found.
Malaria Minute, 10 January 2020
A mechanism of resistance to artemisinin is identified and researchers find that breastfeeding could help to prevent malaria in babies.
Malaria Minute, 3 January 2020
Researchers from the Pasteur Institute discover molecules that can kill the malaria parasite and researchers from LSTM identify a resistance mechanism for insecticides used on bed nets.
Malaria Minute, 27 December 2019
Gene drives prove most efficient in the introduction of a transgene in populations of Anopheles stephensi mosquitoes.
Malaria Minute, 20 December 2019
Researchers from the Walter and Eliza Hall institute identify a new drug which blocks plasmepsin, a critical enzyme in gametocyte production.
Another important property of Artemisia plants. Might help us to better understand the high efficacy against tropical diseases. Just published in PPIJ! See pdf attached
And as Artemisia afra is endemic in so many African countries and used since generations as traditional medicine against malaria no further pre-clinical trials are required as per WHO/EDM/TRM/2000.1
This traditional use is recognized by WHO in the October 2019 statement WHO-CDS-GMP-2019.14
