i have lived here in Tanzania for almost 18 years now. i was in Kenya prior to that working with pyrethrum as an effective repellent and killer.since coming to Tanzania i have tried and tested so many formulas on the market as well as created some of my own. at one stage i was working with the head of the Malaria campaign here Alex Mwita based at the world health organisation offices in Dar es Salaam. when i came here early 2000 i found breeding grounds were the biggest issue as everywhere there was standing water as well as rivers with steady corners allowing breeding.
We talk about asymptomatic, submicroscopic plasmodial infections as potentially being a threat to the elimination of malaria. This is, of course, partly because such infections are not normally treated; especially not in rural endemic areas where laboratory facilities are limited. An aggravation of the situation is when parasitaemias are so low that they cannot be detected by molecular diagnosis (where available) either. But obstacles to elimination are probably even greater than has been realized.
Progress in malaria elimination across the Asia-Pacific is at critical cross-roads, threatened by the spread of multidrug resistant falciparum malaria and continued transmission among marginalized and mobile populations living and working in conditions beyond the reach of traditional malaria control interventions.
As you probably do, I eagerly check MalariaWorld almost every day, and when I have something to contribute, post a blog or comment. But I am disappointed by the lack of responses to my contributions, or to those from all of you. How can we improve this?
Since almost 10,000 people are connected thru MalariaWorld, we might make real progress if we can all contribute. I want to end malaria sooner, not later. Do you agree?
Amiodarone which is used to control irregular heartbeat also has a protective effect in malaria. It triggers eryptosis and the clearance of malaria infected erythrocytes. In Plasmodium berghei infected mice amiodarone injections increased the survival. It is interesting to note that amiodarone is also active against other tropical diseases like Chagas or Leishmaniasis, both in vitro and in vivo, probably by disrupting the parasites' Ca(2+) homeostasis,
Yesterday, August 20th, was World Mosquito Day, which may seemingly sound like a day to honor the mosquito. Yet, more often than not, the narrative that permeates posts and notifications for this awareness day details of how bothersome the mosquito is, how undesirable, and how evil. Communicators may knowingly or unknowingly paint a portrait of a mosquito who intentionally picks up pathogens involved with spreading malaria, Zika, West Nile, or another, then buzzes deviously around spreading them to any and all unsuspecting humans like pollinating honey bees.
It is valuable and refreshing to see contributions to strategies for malaria suppression in Africa from other disciplines, such as economics. Killeen and Reed pointed out that the portfolio effect cushions mosquito populations and malaria transmission against vector control interventions.(Killeen GF, Reed TE. Malar J. 2018 Aug 10;17(1):291. doi: 10.1186/s12936-018-2441-z.) Thus it must be considered when planning a strategy for Africa.
Organisation: Sanger Institute, UK
Salary in the region of £47,812 - £57,853 (Principal Software Developer) or £40,850 - £49,428 ( Senior Software Developer) plus excellent benefits
Fixed term for 2 years with possibility of extension (dependent on external funding)
Job Reference: 83174
Deadline for applications: 15th September 2018