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Hypnozoite activation demonstrated

January 6, 2020 - 01:34 -- Miles Markus

The progression to schizont formation of individual activated hypnozoites has been reported for the first time. This means that it is probably no longer appropriate to use the words "theory" and "hypothesis" when talking about hypnozoites in relation to malarial relapse. The link to the important publication concerned (by Voorberg-van der Wel et al.) is:

https://doi.org/10.1038/s42003-019-0737-3

 

Podcast: DNA Methylation Inhibitor Molecules Kill Plasmodium Parasites

January 3, 2020 - 18:12 -- Malaria Minute

Malaria Minute, 3 January 2020

Researchers from the Pasteur Institute discover molecules that can kill the malaria parasite and researchers from LSTM identify a resistance mechanism for insecticides used on bed nets.

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Artemisia afra and blood pressure

December 17, 2019 - 20:03 -- Pierre Lutgen

 

Another important property of Artemisia plants. Might help us to better understand the high efficacy against tropical diseases.  Just published  in PPIJ! See pdf attached

 

And as Artemisia afra is endemic in so many African countries and used since generations as traditional medicine against malaria no further pre-clinical trials are required as per WHO/EDM/TRM/2000.1    

This traditional use is recognized by  WHO in the October 2019 statement WHO-CDS-GMP-2019.14

Life cycle of Plasmodium

December 16, 2019 - 11:37 -- Miles Markus

Attention is drawn to a paper (by G. Franken, J. Richter, and A. Labisch) which points out, quite rightly, that it would be appropriate for more research on aspects of the life cycle of Plasmodium species that infect humans to be carried out, using modern techniques. The current "liver and blood" concept of the life cycle should not be regarded as the final "word" on the subject.

Link to the publication:

https://doi.org/10.1007/s00436-019-06564-8

Podcast: World Malaria Report Places Emphasis on Pregnant Women and Children

December 10, 2019 - 09:42 -- Malaria Minute

Malaria Minute, 6 December 2019

The WHO publish their annual World Malaria Report which, this year, places emphasis on protecting pregnant women and children from malaria.

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The World Malaria Report 2019 is out!

December 4, 2019 - 14:34 -- Malaria World

More pregnant women and children protected from malaria, but accelerated efforts and funding needed to reinvigorate global response, WHO report shows

The World malaria report 2019 provides a comprehensive update on global and regional malaria data and trends. The report tracks investments in malaria programmes and research as well as progress across all intervention areas: prevention, diagnosis, treatment, elimination and surveillance. It also includes dedicated chapters on the consequences of malaria on maternal, infant and child health, the “High Burden to High Impact” approach as well as biological threats to the fight against malaria.

The 2019 report is based on information received from more than 80 countries and areas with ongoing malaria transmission. This information is supplemented by data from national household surveys and databases held by other organizations.

Download the World Malaria Report 2019

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