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Realism will work best for attacking malaria

December 26, 2009 - 15:19 -- William Jobin

While it might appear that the call for eradication will bring out lots of enthusiasm, it is hard to see how we can mount a global program, based on fantasy.

And let's admit that the Gates and Clinton Foundations mean well but are divorced from reality, USAID and the PMI are mired in decades of bureaurocratic tangles, and the UN and WHO left the scene a long time ago, so the attack on malaria in Africa will progress as Africa progresses.

Realism will work better than fantasy.

Let's take Africa, where most malaria deaths occur. A realistic strategy would be to start in the stable, most democratic countries, and gradually develop competent national programs, employing nationals who live in the malaria zone, who can progress upward in their civil service by making progress against malaria in small and carefully measured increments.

So they would reduce malaria prev in school kids by 10% each year, at a cost within the national budget realities. That gives us a solid foundation for progress. Forget the magic bullets and fantasy. Malaria control takes careful application of proven methods - all of them - in a rational strategy that reflects budget realities as well as the ecology of malaria.

Start with the solid countries, where investments will not be wasted on some dictator and his cronies. Start with Senegal, Mali and Ghana. With Tanzania and Mozambique, Malawi, Zambia, Botswana and blessed South Africa. Grow those programs slowly and carefully. Use them as training grounds for folks around them who speak the same language. Realize that we are dealing with Arabic, English, French, Portuguese and Swahili.

Final note: I think it is the third law of for attacking malaria in Africa - The dictators are as dangerous as the mosquitoes.

Willy

WMS (Web Map Service) Server for geo-spatial information: Developement for emergency case management?

December 18, 2009 - 00:40 -- Usa Lek-Uthai
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Develop a mobile rapid data collection and referral systems and to update emergency and severity patients and also priority of disaster information’s on a server in real time has been recognized.

Recently, mobile devices such as PDA, Mobile Phones, GPS, which can be connected each other easily, are becoming available in the market. Internet connection through mobile phone is available (such as GPRS). The development of a WMS (Web Map Service) Server for geo-spatial information sharing is interesting.

 

World Malaria Report 2009: Are we moving in the right direction?

December 15, 2009 - 21:21 -- Bart G.J. Knols

It's that time of the year when we all get to see how well the battle against malaria is progressing: The World Malaria Report 2009 came out today. And, overall, there is much, much progress. Regretfully, and well-documented this time, there are also worries...

 

Evolutionary biology, evolution-proof insecticides and malaria control

December 11, 2009 - 13:49 -- Yannis Michalakis

Yannis Michalakis & François Renaud GEMI, CNRS-IRD UMR 2724, Montpellier, France Yannis.Michalakis@mpl.ird.fr, Francois.Renaud@mpl.ird.fr

 

Evolutionary thinking started pervading vector control strategies and planning since it was used to explain and manage insecticide resistance. More recently it has been used in the planning of GMMs (Genetically Modified Mosquitoes).

 

A new promising avenue was recently opened by Andrew Read and his colleagues.

Clever use of mobile phone data to better control malaria?

December 11, 2009 - 08:22 -- Bart G.J. Knols

Andy Tattem and colleagues published a really interesting study in the Malaria Journal yesterday. They conclude from the study that anonymous mobile phone records provide valuable information on human movement patterns in areas that are typically data-sparse. Estimates of human movement patterns from Zanzibar to mainland Tanzania suggest that imported malaria risk from this group is heterogeneously distributed; a few people account for most of the risk for imported malaria.

Loop-Mediated Isothermal Amplification Method (LAMP): Low and Effective cost Novel Tool for Molecular Public Health

December 9, 2009 - 05:35 -- Usa Lek-Uthai

This technique need not to have even high cost equipments (especially PCR or GelDoc or refrigerator). The specific LAMP primer set consist of F3(forward outer primer), B3 (backward outer primer), FIP (forward inner primer), and BIP (backward inner primer) These primers will be designed using the Primer Explorer program (http://www.loopamp.eiken.co.jp) to amplify the 18S ribosomal

Standard Distance Ellipse (SDE): a Novel Ellipsoid Spatial Analysis (NESA) for disease control

December 1, 2009 - 05:05 -- Usa Lek-Uthai

The distribution patterns of malaria incidence, using GIS, the geographically map that contain X and Y coordinates for computerized files on digitized base maps and the mosaic imageries from aerial photographs of each household should be created. The use of Standard Distance Ellipse (SDE) to measure the dispersion of the prevalence around the mean centre of malaria cases and points.

turnover of mRNA:gene transfection with new physical equipment (microporation)

November 30, 2009 - 07:25 -- Usa Lek-Uthai

Transfection system which is a new tool for RNAi (gene silencing) workflow; the study of human genome of 30000-40000 encoded protein , the protein function(s) are unknown or a little is known. the former era was studied on molecular biology which is the mutant phenotype sudies (Forward genetic). Recently there is reverse genetic which will rapidly results and clarify such as;

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