Project: Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)
Deadline for applications: May, 3rd 2019
The Barcelona Institute for Global Health (ISGlobal) is the fruit of an innovative alliance between academic, government, and philanthropic institutions to contribute to the efforts undertaken by the international community to address the challenges in global health.
ISGlobal is a research center in international health whose ultimate goal is to help close the gaps in health disparities between and within different regions of the world. For this, we engage in knowledge generation, translation and implementation. ISGlobal is a WHO Collaborative Center for Malaria Control, Elimination and Eradication.
Malaria remains a public health problem across the developing world. After achieving remarkable advances from 2000 to 2015, the global fight against malaria has stalled. The World Malaria Report 2018 estimates an increase to 219 million cases in 2017 compared to 216 million in 2016. We are currently not on track to achieve the goals proposed by WHO in the Global Technical Strategy for Malaria 2016-2030 (GTS).
Vector control, our most effective prevention strategy, is now doubly threatened by residual transmission and insecticide resistance. New tools are needed to control residual transmission, one of the key liabilities of vector control today.
Ivermectin is an endectocide, a drug with excellent safety profile that can kill ecto- and endo-parasites, as well as mosquitoes fed on treated humans or animals. Mass drug administration (MDA) of ivermectin to humans and/or livestock holds the potential to complement the malaria toolbox by tackling residual transmission and help overcoming insecticide resistance.
BOHEMIA is a Unitaid funded, 4-year project that combines evidence generation and stakeholder engagement to create an enabling environment for ivermectin as a first-in-class endectocide for malaria prevention. This will be achieved by generating evidence to support a WHO policy recommendation, briefing and engagement of country and regional leaders and civil society in order to forge country ownership and create demand, as well as ensuring supply of quality product by enabling manufacturer engagement as suppliers of quality, high volume/low cost product sufficient for malaria indication.
Evidence generation will consist of two independently powered cluster-randomized clinical trials in Tanzania and Mozambique with analysis of impact on infection incidence, as well as supporting entomological outcomes.
ISGlobal is looking for an experienced Biostatistician for the BOHEMIA project.
The Senior Biostadistician will work across malaria projects in during the first year before focusing 100% on BOHEMIA until project end.
Barcelona - Campus Clinic
Essential duties and responsibilities
- Contributes to study design for project clinical trials and allied studies
- Contributes to data management including:
- Database design
- Data flow
- Data quality assurance
- Data cleaning as needed
- Generates the first draft of the analytical plan for every work package (epidemiology, entomology, safety, animal health, economics…) and incorporates input from the corresponding leaders
- Creates analytical models to help reaching conclusions and making decisions based on the trial results
- Contributes to data visualization
- Contributes to manuscript drafting
- Proposes different uses for already collected databases
- Works with other malaria projects within ISGlobal to generate synergies and advance institutional goals
- Participates in internal malaria and/or biostatistics meetings
- Works towards assuring timely and appropriate data and safety monitoring of trials
- Contributes to epidemiological modelling and meta-analysis
- PhD in biostatistics
- Bachelor degree in mathematics, epidemiology, biological or medical sciences
- At least 5 years of experience with different types of clinical trials and across the clinical trial lifecycle, including study design, protocol development, data management and analysis.
- Expert management of statistics software at efficient program level to assure reproducibility of data analysis
- Experience with version control
- Experience with data management systems
- Excellent communications and collaboration skills, experience working in diverse cultures
- Previous experience in malaria
- Previous experience in prevention trials, including vector or vaccines
- Working experience in Spanish or Portuguese
- Experience with Stata, R, Java or Python
- Familiarity with Open Clinica, RedCap, and ODK
- Results-oriented approach to problem solving
- Accustomed to team work
- Ability to work independently where necessary
- This position requires international travel, up to 4 weeks/year, including site visits to rural Tanzania and Mozambique
- Compensation for this position will be based on the applicant’s experience and qualifications
- The starting date is as soon as possible
- Interviews will be done on a rolling basis; hiring of matching candidates might occur before the deadline
How to apply
Applicants must send a CV and a cover letter by email to firstname.lastname@example.org, with the subject heading BOHEMIA_Biostatistician_ March19. The closing date for the receipt of applications is May, 3rd 2019.
Applications will be accepted until 17.00 CET of the closing date.
Only shortlisted candidates will be contacted.
Don't forget to mention MalariaWorld when applying for this position!