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CLOSED: Job: Postdoctoral Fellow malaria vaccine candidates

January 20, 2017 - 10:46 -- MalariaWorld Jobs

Position: Postdoctoral Fellow
Organization: The Sanger Institute Malaria Programme
Salary: £31,115 to £39,004 plus excellent benefits
Two years fixed term
Closing date for applications:
9th February 2017

The Sanger Institute Malaria Programme develops and applies high-throughput tools and technologies for malaria research in order to understand malaria biology and identify and prioritise new intervention targets. One particular area of focus is host-parasite interactions, such as that between the major Plasmodium falciparum vaccine candidate PfRH5 and its human receptor Basigin. Identifying and studying these interactions sheds light on the biological story of human-parasite coevolution and informs the process of vaccine development.

There is now an opening for a two-year post-doctoral fellowship position working in the Rayner lab to prioritise vaccine targets operating during Plasmodium erythrocyte invasion. A recent large-scale screen has identified several promising new vaccine candidate leads. The postdoctoral fellow will apply P. falciparum erythrocyteinvasion and phenotyping assays, along with other cellular and molecular tools, to study these candidates in more depth. The project will require working closely with other scientists at the Sanger Institute and also partners in the UK, USA and in malaria endemic countries. The successful applicant will be independent and a self-starter, keen to make the most of this exciting opportunity. While this is a funded position, the rich biology has many possibilities for the development of new independent projects, and career development and support are a key element of the role.

Essential Skills

  • PhD in molecular and cell biology
  • Outstanding communication skills, to ensure good interactions across multiple research teams; able to communicate effectively about complex technical matters with both experts and non-experts
  • Excellent organization and record keeping skills
  • Independence and motivation, a self-starter and problem solver
  • Ability to deliver high-quality scientific outputs

Ideal Skills

  • Evidence of publication record
  • Experience performing lab-based experimental projects in malaria endemic settings
  • Experience working with Plasmodium parasites


Other information
The Sanger Institute is a charitably funded research centre focused on understanding the role of genetics in health and disease. We use state of the art large-scale genomic approaches to drive world-leading projects to uncover the basis of genetic and infectious disease. Our goal is to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens.

The Institute is located near Cambridge, UK on the stunning Wellcome Genome Campus. This growing and dynamic site is the British hub of genomic science. It hosts the European Bioinformatics Institute (EBI), Open Targets, a Biodata Innovation Centre and will soon host Genomics England Limited’s 100,000 Genomes Sequencing Centre. The Campus is also home to Wellcome Genome Campus Connecting Science. Connecting Science inspires new thinking, sparks conversation and supports learning by drawing on the ground-breaking research taking place on the Campus. Its mission is to enable everyone to explore genomic science and its impact on research, health and society.

To help researchers to develop their skills and networks, the Institute hosts a range of scientific seminars with internal and invited speakers, scientific group meetings and skills development workshops.

Our Benefits include: Defined Contribution Pension Scheme, Group Income Protection, Healthcare scheme, Childcare Vouchers, Workplace Nursery and 25 days Annual Leave, increasing by one day per year up to a maximum of 30, plus Bank Holidays. We also have a gym, two cafes, dining facilities, and a free campus bus service. Our thriving Sports and Social Club provides many opportunities to meet with people working across the campus.
Wellcome Trust Sanger Institute welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status.

Please include a covering letter and CV with your application. 
Closing date for applications: 9th February 2017, however applications will be considered and reviewed on an on-going basis and therefore the post may be filled before the deadline.

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