Global Malaria News
An international research has found that malaria parasite genomes are shaped by parasite-specific gene families, and that this genome organization strongly correlates with the parasite's virulence. The findings highlight the importance of spatial genome organization in gene regulation and the control of virulence in malaria parasites.
Disrupting two genes involved in the preservation of RNA molecules inhibits the ability of the male form of the malaria parasite to mature and be transmitted from human blood into mosquitoes, interrupting a key stage in the parasite's life-cycle and cutting off an important step in the spread of the disease.
In a context of overuse of insecticides, which leads to the selection of resistant mosquitoes, it is already known that this resistance to insecticides affects interactions between mosquitoes and the pathogens they transmit. Researchers demonstrate that mechanisms of insecticide resistance, observed in Culex quinquefasciatus vector, impact the transmission of West Nile virus.
Wherever possible, researchers should not just focus on mosquito behavior when working to eliminate malaria, but must also consider how humans behave at night when the risk of being bitten by an infected mosquito is highest.
New from MESA: Open consultation on WHO prioritization framework for the R&D of malaria health products
Categories: Special Feature
A type of mosquito that transmits malaria has been detected in Ethiopia for the first time, and the discovery has implications for putting more people at risk for malaria in new regions.
Question: Can malaria be transmitted through oral sex? Answer: No. Malaria cannot be sexually transmitted, including oral sex. Malaria is a vector-borne parasite and is transmitted to humans via the bite of an infected mosquito. As the malaria parasite resides in blood, it can also be transmitted via blood transfusion or via donated organs (though most countries […]
Question: If one doesn’t complete the malaria drug being prescribed, and takes multivitamin due to no appetite towards eating and later stop, does this cause the person spitting uncontrollable. Answer: I am not aware of any link between failure to complete a course of malaria medication and excess saliva, nor any link with taking multivitamins. The main […]
I am working with rural African communities where we are struggling with contamination of farm products with residues from indoor residual spraying (ban on exports) - and are concerned about contamination of humans as well. Stepped up treatment of all persons diagnosed with malaria with AL. How do the mosquitoes get infected by the parasite so that they can infect humans?
Do you have a questions about malaria? Ask our experts!
Proposals to fight malaria by 'driving' genes that slow its spread through mosquitoes is a high-risk, high-reward technology that presents a challenge to science journalists, according to a new report aimed at stimulating a fruitful, realistic public discussion of 'post-normal' science and technology.
Scientists have provided, for the first time, evidence which links the ability of red blood cells infected with the malaria parasite to bind to the cells lining the blood vessels of the brain, with the clinical syndrome cerebral malaria.
Categories: Special Feature
A vaccine against fatal pregnancy malaria shows promising results in the first tests in humans. The new study has taken a vaccine all the way from discovery of a mechanism through development and production to clinical trials in humans.
A newly discovered protein that is crucial for egg production in mosquitoes opens a possibility for 'mosquito birth control.' The approach might offer a way to reduce mosquito populations in areas of human disease transmission without harming beneficial insects such as honey bees.
Researchers have looked at the efficacy of using a novel artemisinin-based combination therapy (ACT), pyronaridine-artesunate, to treat malaria in areas where resistance to other ACTs is becoming a problem. The analysis finds it at least as effective as the currently used ACTs, if not better.
Insecticide-infused mosquito netting is in widespread use around the world to limit the spread of mosquito-borne diseases, such as malaria. Researchers have now come up with a technique that measures how much insecticide is found on the surface of these nets -- paving the way for efforts to determine how long the nets are effective.
Question: Does malaria treatment, especially with paluta injection cause insomnia. I have experienced this twice. Answer: If you are referring to injection with artemether (sold as Paluther), then yes, trouble sleeping has been recorded as a possible side effect. However, it should not persist for long after the medication has been administered, so you should consult […]
Researchers have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function leading to parasite death.
Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasite Plasmodium vivax, which can lay dormant for months or even years. Researchers have reported a new drug that could eliminate liver-stage malaria parasites completely. Using an insect virus, known as a baculovirus, the researchers investigated the ability of baculovirus to mediate innate immunity against malaria infection. This work could pave the way for developing new and more effective antimalarial treatments.