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Global Malaria News

Discovery of malaria parasite's clock could pave way to new treatments

Science Daily - May 14, 2020 - 18:35
The parasite that causes malaria has its own internal clock, explaining the disease's rhythmic fevers and opening new pathways for therapeutics.

Malaria vaccine: Could this 'ingredient' be the secret to success?

Science Daily - May 13, 2020 - 15:14
Researchers have identified a microscopic 'ingredient' that can be added to a malaria vaccine for efficient protection against the deadly pathogen.

Malaria mosquitoes eliminated in lab by creating all-male populations

Science Daily - May 12, 2020 - 17:44
A modification that creates more male offspring was able to eliminate populations of malaria mosquitoes in lab experiments.

Blood test a potential new tool for controlling infections

Science Daily - May 11, 2020 - 15:26
Researchers have developed a new approach to detecting a person's immunity to an infectious disease -- providing valuable details about whether and when a person was exposed to the infection. The test was developed for detecting recent exposure to malaria, but the research team are now working to adapt it to detect previous exposure to the coronavirus that causes COVID-19. By providing a detailed picture of when an infection spread in a community, the test offers new opportunities for improving infection control and elimination strategies -- particularly in lower income countries.

New computational method unravels single-cell data from multiple people

Science Daily - May 6, 2020 - 16:37
A new computational method for assigning the donor in single cell RNA sequencing experiments provides an accurate way to unravel data from a mixture of people. The Souporcell method could help study how genetic variants in different people affect which genes are expressed during infection or response to drugs, and help research into transplants, personalized medicine and malaria.

Malaria risk is highest in early evening

Science Daily - May 4, 2020 - 15:40
Wide-scale use of insecticide-treated bed nets has led to substantial declines in global incidences of malaria in recent years. As a result, mosquitoes have been shifting their biting times to earlier in the evening and later in the morning.

Designing drugs to combat drug-resistant malaria

Science Daily - April 30, 2020 - 21:09
For the first time, researchers have shown a key difference in the three-dimensional structures of a key metabolic enzyme in the parasite that causes malaria compared to its human counterpart.

Smart interventions reduce malaria transmission by 75%

Science Daily - April 27, 2020 - 14:25
Mass drug administration and vector control can help eliminate malaria. A vector refers to an organism that transmits infection, as mosquitoes infected with parasites transmit malaria to people.

Research reveals a new malaria vaccine candidate

Science Daily - April 22, 2020 - 17:29
In a study that could lead to a new vaccine against malaria, researchers have found antibodies that trigger a 'kill switch' in malarial cells, causing them to self-destruct.

Genetic variation not an obstacle to gene drive strategy to control mosquitoes

Science Daily - April 16, 2020 - 19:18
New research from entomologists clears a potential obstacle to using CRISPR-Cas9 'gene drive' technology to control mosquito-borne diseases such as malaria, dengue fever, yellow fever and Zika.

Low-cost imaging system poised to provide automatic mosquito tracking

Science Daily - April 15, 2020 - 21:14
Mosquito-transmitted diseases such as malaria, dengue and yellow fever are responsible for hundreds of thousands of deaths every year. A new low-cost imaging system could make it easier to track mosquito species that carry disease, enabling a more timely and targeted response.

Deadliest malaria strain protects itself from the immune system

Science Daily - April 13, 2020 - 17:28
The parasite causing the most severe form of human malaria uses proteins to make red blood cells sticky, making it harder for the immune system to destroy it and leading to potentially fatal blood clots. New research has identified how the parasite may control this process.

Stuttering DNA orchestrates the start of the mosquito's life

Science Daily - April 9, 2020 - 14:03
There are large parts of the DNA that are not used for making proteins. This is called 'junk DNA', because its function remained unclear for a long time. However, a certain type of junk DNA that is found in mosquitoes and which repeats itself dozens of times, known as 'satellite DNA', has now been shown to play an essential role in the early development of mosquito embryos.

Experimental anti-malarial drug shows promise in first clinical trial

Science Daily - April 8, 2020 - 16:55
Malaria is a leading killer of children worldwide, and new drugs are needed. New research reports encouraging early clinical results with a new compound.

Is your coffee contributing to malaria risk?

Science Daily - March 9, 2020 - 13:30
Researchers estimate 20% of the malaria risk in deforestation hot spots is driven by the international trade of exports including: coffee, timber, soybean, cocoa, wood products, palm oil, tobacco, beef and cotton. The results of the study can be used for more demand-side approaches to mitigating malaria incidence by focusing on regulating malaria-impacted global supply chains.

Novel compound sparks new malaria treatment hope

Science Daily - March 4, 2020 - 19:15
A novel class of antimalarial compounds that can effectively kill malaria parasites has been developed. In preclinical testing, the compounds were effective against different species of malaria parasites, including the deadly Plasmodium falciparum, and at multiple stages of the parasite lifecycle. The compounds could overcome existing issues of parasite drug resistance. The researchers hope that drugs based on these early compounds will soon enter phase 1 clinical trials.

How malaria detects and shields itself from approaching immune cells

Science Daily - February 18, 2020 - 17:43
Malaria parasites can sense a molecule produced by approaching immune cells and then use it to protect themselves from destruction, according to new findings.

Eco-friendly way to stop mosquitoes

Science Daily - February 13, 2020 - 14:07
An innovative -- and inexpensive -- technique targets mosquito larvae where they live.

How the malaria parasite grows and multiplies

Science Daily - February 11, 2020 - 17:15
Scientists have made a major breakthrough in understanding how the parasite that causes malaria is able to multiply at such an alarming rate, which could be a vital clue in discovering how it has evolved, and how it can be stopped. For the first time, scientists have shown how certain molecules play an essential role in the rapid reproduction of parasite cells, which cause this deadly disease.

Discovery paves path forward in the fight against the deadliest form of malaria

Science Daily - February 8, 2020 - 14:43
Scientists have identified a key molecule involved in the development of cerebral malaria, a deadly form of the tropical disease. The study identifies a potential drug target and way forward toward alleviating this condition for which few targeted treatments are available.

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