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Malaria research. Read the latest medical research on malaria, including new control methods and malaria treatments.
Updated: 55 min 26 sec ago

How deadly parasites 'glide' into human cells

October 13, 2020 - 13:02
A group of scientists provide insights into the molecular structure of proteins involved in the gliding movements through which the parasites causing malaria and toxoplasmosis invade human cells.

Chemists create new crystal form of insecticide, boosting its ability to fight mosquitoes and malaria

October 12, 2020 - 19:20
Through a simple process of heating and cooling, researchers have created a new crystal form of deltamethrin -- a common insecticide used to control malaria -- resulting in an insecticide that is up to 12 times more effective against mosquitoes than the existing form.

Immune evasion strategy used by Malaria-causing parasite

October 9, 2020 - 12:49
A team of researchers has found that the Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections.

New model may explain rarity of certain malaria-blocking mutations

October 8, 2020 - 18:21
A new computational model suggests that certain mutations that block infection by the most dangerous species of malaria have not become widespread in people because of the parasite's effects on the immune system.

How malaria parasites withstand a fever's heat

October 5, 2020 - 21:08
The parasites that cause 200 million cases of malaria each year can withstand feverish temperatures that make their human hosts miserable. Now, a team is beginning to understand how they do it. The researchers have identified a lipid-protein combo that springs into action to gird the parasite's innards against heat shock. Understanding how malaria protects its cells against heat and other onslaughts could lead to new ways to fight tough-to-kill strains, researchers say.

Repurposed anti-malarial compounds kill diarrheal parasite, study finds

October 1, 2020 - 15:36
A class of compounds used for malaria treatment also kill the intestinal parasite Cryptosporidium, a leading cause of diarrheal disease and death in children that has no cure, a multi-institution collaboration of researchers found in a new study.

New tool mimics human skin to allow detailed study of mosquito biting

September 23, 2020 - 16:46
Scientists have developed a tool for studying the biting behavior of common pathogen-carrying mosquitoes.

CRISPR-based malaria testing on-the-fly

September 21, 2020 - 19:26
A multi-disciplinary research collaboration created a field-applicable, ultrasensitive diagnostic assay that specifically detects DNA sequences from all Plasmodium species in symptomatic and asymptomatic malaria. The new malaria diagnostic method combines an optimized 10-minute rapid sample preparation protocol with the CRISPR-based SHERLOCK system to enable highly specific and sensitive Plasmodium detection in another 60 minutes in simple reporter devices.

How Dantu blood group protects against malaria, and how all humans could benefit

September 16, 2020 - 15:35
The secret of how the Dantu genetic blood variant helps to protect against malaria has been revealed for the first time. The team found that red blood cells in people with the rare Dantu blood variant have a higher surface tension that prevents them from being invaded by the world's deadliest malaria parasite, Plasmodium falciparum.

COVID-19 virus uses heparan sulfate to get inside cells

September 15, 2020 - 19:24
Researchers discovered that the SARS-CoV-2 virus can't grab hold of cell receptor ACE2 without a carbohydrate called heparan sulfate, which is also found on lung cell surfaces -- disrupting that interaction with a repurposed drug may help treat COVID-19.

Rising temperatures could shift US West Nile virus transmission

September 15, 2020 - 14:59
West Nile virus spreads most efficiently in the US at temperatures between 24-25 degrees Celsius (75.2-77 degrees Fahrenheit), a new study shows.

Human activities promote disease-spreading mosquitoes; more study needed for prevention

September 14, 2020 - 21:29
Disease-spreading mosquitoes may be more likely to occupy areas impacted by human activities like pesticide use and habitat destruction, than they are areas less disturbed by humans, a recent study found.

New malaria transmission patterns emerge in Africa

August 28, 2020 - 12:10
An international study reveals how future climate change could affect malaria transmission in Africa over the next century.

Mosquito immune system mapped to help fight malaria

August 27, 2020 - 18:12
Scientists have created the first cell atlas of mosquito immune cells, to understand how mosquitoes fight malaria and other infections. Researchers discovered new types of mosquito immune cells, including a rare cell type that could be involved in limiting malaria infection. The findings offer opportunities for uncovering novel ways to prevent mosquitoes from spreading the malaria parasite to humans and break the chain of malaria transmission.

Study explores the association of malaria, HIV with anemia during pregnancy

August 14, 2020 - 17:10
Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections, according to researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.

Malaria discovery could expedite antiviral treatment for COVID-19

August 11, 2020 - 16:01
New research into malaria suggests targeting enzymes from the human host, rather than from the pathogen itself, could offer effective treatment for a range of infectious diseases, including COVID-19.

New set of channels connecting malaria parasite and blood cells

July 30, 2020 - 13:26
Researchers have discovered another set of pore-like holes, or channels, traversing the membrane-bound sac that encloses the deadliest malaria parasite as it infects red blood cells. The channels enable the transport of lipids -- fat-like molecules -- between the blood cell and parasite, Plasmodium falciparum. The parasite draws lipids from the cell to sustain its growth and may also secrete other types of lipids to hijack cell functions to meet its needs.

The mystery of the less deadly mosquito nets

July 28, 2020 - 15:35
Research shows that insecticide-treated mosquito nets, the mainstay in the global battle against malaria, are not providing the protection they once did - and scientists say that's a cause for serious concern in tropical and subtropical countries around the globe.

Getting a grasp on India's malaria burden

July 3, 2020 - 13:49
A new approach could illuminate a critical stage in the life cycle of one of the most common malaria parasites.

Tracking the spread of mosquito insecticide resistance across Africa

June 25, 2020 - 18:07
In a step toward better control of the mosquitoes that transmit malaria, researchers have mapped the patterns of insecticide resistance in Anopheles gambiae mosquitoes across Africa. The new study found that resistance to five mainstream insecticides increased dramatically between 2005 and 2017.