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Malaria research. Read the latest medical research on malaria, including new control methods and malaria treatments.
Updated: 6 min 18 sec ago

Genes tell the story of how the Asian tiger mosquito spread

4 hours 56 min ago
Over the last 40 years, the Asian tiger mosquito, Aedes albopictus, has invaded every continent thanks to the transportation of its eggs via human trade and transportation. Researchers have now used the genomes of the mosquitoes to track the history of the invasion and expansion of the species through Albania, Italy, and Greece.

An unreported Zika outbreak in 2017 detected through travel surveillance and genetics

7 hours 42 min ago
By sequencing virus genomes from infected travelers, analyzing travel patterns and mosquito modeling, researchers unearthed a spike in Zika cases from travelers returning from Cuba during the summer of 2017 that was not captured by local reports.

Malaria expert warns of need for malaria drug to treat severe cases in US

August 19, 2019 - 21:57
The US each year sees more than 1,500 cases of malaria, and currently there is limited access to an intravenously-administered (IV) drug needed for the more serious cases.

Monkey malaria breakthrough offers possible cure for relapsing malaria

August 15, 2019 - 14:15
A breakthrough in monkey malaria research could help scientists diagnose and treat a relapsing form of human malaria.

Mosquito 'spit glands' hold key to curbing malaria, study shows

August 12, 2019 - 17:08
Mosquitoes can harbor thousands of malaria-causing parasites in their bodies, yet while slurping blood from a victim, they transmit just a tiny fraction of them. In an effort to define precisely the location of the parasite bottleneck, scientists say they have discovered that the parasites are stopped by a roadblock along the escape route in the insect's spit glands, a barrier that could potentially serve as a novel target for preventing or reducing malarial infection.

Selective antibiotics following nature's example

July 30, 2019 - 16:53
Chemists develop selective agents to combat infectious diseases -- based on the structures of natural products.

Keeping parasites from sticking to mosquito guts could block disease transmission

July 30, 2019 - 16:52
Infections such as Chagas disease, African sleeping sickness, and leishmaniasis are caused by a group of microorganisms called kinetoplastids. In a new study, a research team used a non-disease-causing kinetoplastid to investigate how these parasites adhere to their insect hosts' insides. Their findings could help in the development of targeted therapies that prevent insects from transmitting these diseases to humans.

Copy-number variants in development of insecticide resistance in malaria mosquitoes

July 26, 2019 - 13:46
Researchers have used whole genome sequencing to understand copy-number variants (CNVs) in malaria mosquitoes and their role in insecticide resistance.

Trapping female mosquitoes helps curb chikungunya virus

July 25, 2019 - 19:09
The US Centers for Disease Control and Prevention (CDC) recently developed an Autocidal Gravid Ovitrap (AGP trap) that attracts and captures female mosquitoes looking for a site to lay eggs. Now, researchers report that AGO traps successfully protected people from infection with chikungunya virus (CHIKV) in communities in Puerto Rico.

Multidrug-resistant malaria spreading in Asia

July 23, 2019 - 12:59
Genomic surveillance has revealed that malaria resistance to two first-line antimalarial drugs has spread rapidly from Cambodia to neighboring countries in Southeast Asia. Researchers discovered that descendants of one multi-drug resistant malaria strain are replacing the local parasites in Vietnam, Laos and northeastern Thailand, and are picking up additional new genetic changes which could further enhance resistance. The study reveals the importance of ongoing genomic surveillance in malaria control strategies.

Understanding the mode of action of the primaquine: New insights into a 70 year old puzzle

July 19, 2019 - 14:21
Researchers have taken significant steps in understanding the way that the anti-malarial drug primaquine (PQ) works, which they hope will lead to the development of new, safer and more effective treatments for malaria.

Getting to zero malaria cases in Zanzibar

July 10, 2019 - 17:19
New research suggests that a better understanding of human behavior at night -- when malaria mosquitoes are biting -- could be key to preventing lingering cases.

How the mosquito immune system fights off the malaria parasite

July 10, 2019 - 17:19
A new study describes the way mosquito immune systems fight malaria parasites using various waves of resistance. The study could lay the groundwork for future research to combat the transmission of malaria, which sickens millions of people across the globe every year.

Why do mosquitoes choose humans?

July 2, 2019 - 22:45
Most of the 3,000+ mosquito species are opportunistic, but researchers are most interested in the mosquitoes that scientists call 'disease vectors' -- carriers of diseases that plague humans -- some of which have evolved to bite humans almost exclusively. One expert is trying to understand how the brain and genome of these mosquitoes have evolved to make them specialize in humans -- including how they can distinguish us from other mammals so effectively.

Botox cousin can reduce malaria in an environmentally friendly way

June 28, 2019 - 16:05
Researchers have found a new toxin that selectively targets mosquitoes. This can lead to innovative and environmentally friendly approaches to reduce malaria.

Malaria hijacks your genes to invade your liver

June 27, 2019 - 15:40
Researchers have identified more than 100 'hijacked' human genes that malaria parasites commandeer to take up residence inside their victim's liver during the silent early stages of infection, before symptoms appear. Before their work only a few such genes were known. The findings could lead to new ways to stop malaria parasites before people get sick and help keep the disease from spreading, via treatments that are less likely to promote resistance.

New high-resolution maps show how to defeat malaria

June 20, 2019 - 03:23
New high-resolution maps show the global burden of Plasmodium falciparum and Plasmodium vivax, the two parasites that cause the majority of malaria cases worldwide.

Human protein that aids development of malaria parasite identified

June 12, 2019 - 13:29
Researchers have discovered that the Plasmodium parasites responsible for malaria rely on a human liver cell protein for their development into a form capable of infecting red blood cells and causing disease. The study suggests that targeting this human protein, known as CXCR4, could be a way to block the parasite's life cycle and prevent the development of malaria.

Combating mosquito-borne diseases with bacteria

June 10, 2019 - 17:01
Viruses, spread through mosquito bites, cause human illnesses such as dengue fever, Zika and yellow fever. A new control technique harnesses a naturally occurring bacterium called Wolbachia that blocks replication of viruses and breaks the cycle of mosquito-borne disease, according to an international team of researchers.

Mosquito control program reduces dengue, costs in Sri Lanka

June 5, 2019 - 17:48
A public health, police, and military partnership to reduce the mosquito population in Sri Lanka resulted in a more than 50% reduction in dengue, as well as cost savings, finds a new study.

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