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Global Malaria News

AMF funds 16.2 million nets for distribution in the Democratic Republic of Congo (DRC) in 2020/21

Against Malaria news - 1 hour 19 min ago

AMF has signed an agreement with the DRC Ministry of Health to fund 16.2 million nets for distribution from June 2020 to March 2021. This represents 67% of DRC’s long-lasting insecticide treated net (LLIN) need for the 2020/21 portion of their three-year rolling universal coverage campaign.

DRC is one of the two most malarious countries in the world with malaria responsible for the deaths of at least 100 children under 5 each day in DRC alone. Malaria is one of the primary health issues in DRC, with high incidence levels seen across the majority of the country.

The nets will be distributed in seven of DRC's 26 provinces, specifically:

  1. Kinshasa: 4.1m nets to protect 7.4m people, distribution during Q2/Q3 2020
  2. Kongo Central: 2.6m nets to protect 4.7m people, distribution during Q2/Q3 2020
  3. Tshopo: 2.2m nets to protect 4m people, distribution during Q3/Q4 2020
  4. Haut Uele: 1.2m nets to protect 2.2m people, distribution during Q3/Q4 2020
  5. Ituri: 3.6m nets to protect 6.5m people, distribution during Q3/Q4 2020
  6. Maniema: 1.7m nets to protect 3m people, distribution in Q1 2021
  7. Bas Uele: 0.8m nets to protect 1.4m people, distribution in Q1 2021

In total, 29 million people will be protected from the bites of malaria-carrying mosquitoes.

These nets have the potential to play a major part in reducing deaths and illness. This quantity of nets could be expected to prevent 10,500 deaths, 5 million cases of malaria and make a material impact on the economy of DRC. It is estimated that the improvement in GDP (Gross Domestic Product), a measure of economic performance, would be about USD 385 million.

AMF allocates individual donations to specific distributions and so far we have allocated 50,310 individual donations from 12,990 donors from 105 countries. These figures will increase as further donations are allocated. Many donations, large and small, help fund these nets.

We will report openly on progress and performance throughout and after the distribution.

Key elements of our agreement include:

  1. AMF is funding 16,200,000 LLINs for distribution in 2020/21
  2. This is a co-funding partnership with non-net costs (shipping, pre-distribution, distribution) funded by the Global Fund
  3. To support accurate data gathering, re-checks of net need numbers will take place by re-visiting a material number of households chosen at random.
  4. Household-level data will be collected on paper or using electronic-devices and then entered into AMF’s Data Entry System (DES) for analysis and verification. This, and the above elements combined, are the basis for a highly accountable distribution.
  5. Post-distribution monitoring of net use and condition (PDMs) will take place every nine months for two and a half years in all districts. AMF will fund this.

Further information via the dedicated distribution page

Other DRC distributions
2019 Equateur and Sud Ubangi
2019 Tanganyika, Haut Katanga and Haut Lomami

Insulin can increase mosquitoes' immunity to West Nile virus

Science Daily - November 13, 2019 - 15:18
A discovery has the potential to inhibit the spread of West Nile virus as well as Zika and dengue viruses. The researchers demonstrated that mammalian insulin activated an antiviral immunity pathway in mosquitoes, increasing the insects' ability to suppress the viruses. Since mosquito bites are the most common way humans are infected with West Nile, stopping the virus among the insects would protect human health.

Scientists identify immune cells linked to malaria-induced anemia through autoantibody production

Science Daily - November 12, 2019 - 16:02
An autoimmune attack on uninfected red blood cells likely contributes to anemia -- a shortage of red blood cells -- in people with malaria.

How the Zika virus can spread

Science Daily - November 11, 2019 - 15:50
The spread of infectious diseases such as Zika depends on many different factors. Researchers were able to generate reliable maps for the transmission risk of the Zika virus in South America.

Mated female mosquitoes are more likely to transmit malaria parasites

Science Daily - November 7, 2019 - 21:07
Female mosquitoes that have mated are more likely to transmit malaria parasites than virgin females, according to a new study.

AMF funds 3.5 million nets for distribution in the Togo in 2020

Against Malaria news - November 1, 2019 - 12:59

AMF has signed an agreement with the Togolese Ministry of Health to fund 3.5 million nets for distribution from June to August 2020. This represents 60% of Togo's long-lasting insecticide treated net (LLIN) need for the universal coverage campaign. The last campaign was in 2017 where AMF funded 2.4 million nets.

The nets will be distributed in four of Togo's five regions: Kara, Centrale, Plateaux and Maritime and will protect 6.3 million people.

The latest Malaria Indicator Survey showed that all of Togo’s regions have a malaria problem that needs to be tackled, with the worst affected being Plateaux region where 47% of children aged 6 to 59 months show a positive result to a malaria microscopy test.

High prevalence may be due in part to increasing levels of insecticide resistance and AMF is evaluating the data to judge whether malaria outcomes can be improved if a portion of the nets funded were PBO nets, as these nets have shown better capability against insecticide-resistant mosquitoes.

The total of 3.5m nets have the potential to play a major part in reducing deaths and illness from malaria. This quantity of nets could be expected to prevent 2,300 deaths, 1.2 million cases of malaria and make a material impact on the economy of Togo. It is estimated that the improvement in GDP (Gross Domestic Product), a measure of economic performance, would be about US$83 million.

AMF allocates individual donations to specific distributions and so far we have allocated 5,220 individual donations from 3,967 donors from 64 countries. We are allocating more donations now so these figures will increase. Many donations, large and small, help fund these nets.

We will report openly on progress and performance throughout and after the distribution.

Key elements of our agreement include:

  • AMF is funding 3,538,200 LLINs for distribution in 2019
  • This is a co-funding partnership with non-net costs (shipping, pre-distribution and distribution costs) funded by the Global Fund
  • To support accurate data gathering
    • all registration data will be collected using electronic devices before being imported into AMF's Data Entry System (DES) for analysis and verification
    • all data collectors will be aware that a random selection of 5% of the households that each register will be re-visited
    • AMF will fund an independent monitoring organisation to be present during registration (and during distribution) in a material number of villages selected at random
  • The above elements are the basis for a highly accountable distribution
  • Post-distribution monitoring of net use and condition (PDMs) will take place every nine months for two and a half years in all districts. AMF will fund this.

AMF activity update: October 2019

Against Malaria news - October 31, 2019 - 16:53

A short update on activities going on this month.

  1. AMF is hiring for two exciting positions - an Operations Manager and a Full Stack Developer.
     
  2. In DRC, the distribution of 1.5 million nets in Équateur province began on 17th October and is being wrapped up in all health zones. Distribution data is being validated and sent to Kinshasa, where it will be entered into AMF's database. In Haut Katanga, the registration of 1.4 million households will now take place with a pilot of electronic data collection in three of the 27 health zones. This will be the first time that our distribution partner, SANRU (Santé Rurale), will conduct electronic data collection and will be a chance to gain experience at scale before the registration of all provinces in 2020 and 2021 is performed electronically. This has pushed back the registration to November. We have signed an agreement with our data entry partner, AGAPE, to put in place a data entry centre in Kinshasa to enter into AMF’s database the registration data collected on paper from the households in the remaining 24 health zones.
     
  3. In Togo, a new agreement has been signed with the Ministry of Health to fund 3.5 million nets for the 2020 campaign. The 24-month PDM has been carried out in all four regions (Savanes, Kara, Centrale and Plateaux) that received 2.4 million nets in 2017. Data was collected using electronic devices and will be sent to AMF shortly. Photos below show the challenges of reaching randomly selected households during the current rainy season.
     
  4. In Ghana, our PDM partner World Vision has completed data collection for the 9-month PDMs in regions that received AMF nets. Data was collected with electronic devices and 1.5% of all households that received AMF-funded nets were visited. The sleeping space coverage across these areas is 62% and the next step will be to discuss this with the National Malaria Control Programme to understand what actions can be taken to improve net usage.
     
  5. In Malawi, our partner the Malawi Red Cross Society has finished PDMs in Central region and data will shortly be imported into our Data Entry System. We have shared initial results with the National Malaria Control Programme who are considering actions to be taken to increase net usage where necessary.
     
  6. In Guinea, we are tendering for a PDM partner to carry out post-distribution monitoring at 9, 18 and 27 months across 1.5% of all households that received AMF-funded nets, collecting data electronically. PDMs will begin in February 2020. Investigations into a possible theft of AMF nets are ongoing, and we will provide a dedicated update in November.
     
  7. In Uganda, our PDM partner organisation Malaria Consortium, with their implementing partner PACE, is carrying out the 30-month PDM in the Eastern region.
     
  8. In PNG, our partner RAM continues to distribute nets on a rolling basis. Distribution has been completed in 5 of the 8 provinces scheduled for the year, with distribution ongoing in the Autonomous Region of Bougainville (ARoB, previously known as North Solomons province). More than 500,000 nets have been distributed in 2019. Orders have been placed for the first province that will receive AMF-funded nets in the 2020 campaign, Milne Bay.
     
  9. In Zambia, the next PDM to take place will be in Eastern province at 18 months post distribution. We have signed an agreement with our partner CHAZ to carry out this work in October and November.
     

Research reveals how malaria parasite plans ahead, preparing blueprint to strike in humans

Science Daily - October 31, 2019 - 15:25
Within seconds after an infected mosquito bites, the malaria parasite navigates the host skin and blood vessels to invade the liver, where it will stay embedded until thousands of infected cells launch malaria's deadly blood-stage infection. Now, for the first time, a team describes how malaria Plasmodium parasites prepare for this journey. Researchers say this knowledge may help identify new strategies to block transmission of the parasite.

Malaria pathogen under the X-ray microscope

Science Daily - October 30, 2019 - 17:27
Malaria is one of the most threatening infectious diseases in the world. An international team has now been able to investigate malaria pathogens in red blood cells in vivo using the BESSY II X-ray microscope and the ALBA and ESRF synchrotron sources. The studies reveal the mechanisms used by active substances to attack the pathogen. This could contribute to improvement of treatment strategies and drugs.

AMF is hiring - Full Stack Developer

Against Malaria news - October 25, 2019 - 17:00

AMF's activities and commitments are steadily increasing, with expected annual distributions of over 20 million nets in the coming years. As a result, AMF is adding to the technology team and is now seeking exceptional candidates for the role of Full Stack Developer, specialising in ASP.Net, VB.Net and SQL Server.

Reporting to AMF's Head of Technology, and working closely with all other members of the AMF team, the successful candidate will have the following skills and experience:

Coding

  • ASP.Net, VB.Net, SQL Server; level of competence: excellent; likely years' experience: 5
  • .Net Core, C#; level of competence: good; likely years' experience: 1 to 2
General
  • Strong analytical capabilities – for both the website functionality and database design
  • Able to focus on detail whilst retaining the bigger picture
  • Strong project and time management skills
  • Self‐motivated with the ability to work to deadlines
  • Strong communication skills at both a technical and non‐technical level
Additional skills
  • Knowledge of non-web coding - i.e. console apps, desktop apps, web services - which may be required to support the site or back‐office users
  • Knowledge and experience of source-control solutions for code (specifically Git)
  • Awareness of social media platforms and how to best integrate/exploit them

The successful candidate is likely to be in the UK/Europe/Africa time zones.

Job description and details of how to apply.

AMF is hiring - Full Stack Developer

Against Malaria news - October 25, 2019 - 17:00

AMF's activities and commitments are steadily increasing, with expected annual distributions of over 20 million nets in the coming years. As a result, AMF is adding to the technology team and is now seeking exceptional candidates for the role of Full Stack Developer, specialising in ASP.Net, VB.Net and SQL Server.

Reporting to AMF's Head of Technology, and working closely with all other members of the AMF team, the successful candidate will have the following skills and experience:

Coding

  • ASP.Net, VB.Net, SQL Server; level of competence: excellent; likely years' experience: 5
  • .Net Core, C#; level of competence: good; likely years' experience: 1 to 2
General
  • Strong analytical capabilities – for both the website functionality and database design
  • Able to focus on detail whilst retaining the bigger picture
  • Strong project and time management skills
  • Self‐motivated with the ability to work to deadlines
  • Strong communication skills at both a technical and non‐technical level
Additional skills
  • Knowledge of non-web coding - i.e. console apps, desktop apps, web services - which may be required to support the site or back‐office users
  • Knowledge and experience of source-control solutions for code (specifically Git)
  • Awareness of social media platforms and how to best integrate/exploit them

The successful candidate is likely to be in the UK/Europe/Africa time zones.

Job description and details of how to apply.

Rhomboid protease in action

Science Daily - October 25, 2019 - 14:14
Rhomboid proteases are clinically relevant membrane proteins that play a key role in various diseases. Using solid-state NMR spectroscopy, researchers have now been able to watch rhomboid proteases in a native lipid environment at work. The obtained dynamic images will be useful for the development of new medication for diseases such as Parkinson's and malaria.

AMF is hiring - Operations Manager

Against Malaria news - October 21, 2019 - 16:00

AMF's activities and commitments are steadily increasing, with expected annual distributions of over 20 million nets in the coming years. In light of this, AMF is adding to the operations team and is now seeking exceptional candidates for the role of Operations Manager.

Reporting to AMF’s Operations Director, and working closely with all the other members of the AMF team, the successful candidate will

  • speak fluent French and English, have excellent interpersonal skills and be able to construct and maintain strong working relationships
     
  • have exceptional organisational skills, with an interest in managing projects to improve outcomes for the poorest communities
     
  • have strong analytical skills, attention to detail and Excel capability
     
  • be open, collegiate and enjoy working in a small, highly impactful team
     
  • be willing to travel to Africa between 6 and 10 weeks per year
     
  • be comfortable learning about applying their skills to AMF's internal operations

Prior experience in international development is not necessary.

Members of the AMF team work remotely. AMF meets all the costs of shared office space where this is preferred.

The successful candidate is likely to be in the UK/Europe/Africa time zones.

Job description and details of how to apply.

Immune reaction causes malaria organ damage

Science Daily - October 21, 2019 - 14:49
Immune cells can be the body's defenders and foes at the same time.

DEET gives humans an 'invisibilty cloak' to fend off mosquito bites

Science Daily - October 17, 2019 - 15:16
Since its invention during the Second World War for soldiers stationed in countries where malaria transmission rates were high, researchers have worked to pinpoint precisely how DEET actually affects mosquitoes.

Acaí berry extracts fight malaria in mice

Science Daily - October 16, 2019 - 16:46
Despite humanity's best efforts to eradicate malaria, the disease struck more than 200 million people in 2017, according to the World Health Organization. Worse yet, the parasite that causes malaria is developing resistance to many antimalarial drugs, including the mainstay, chloroquine. Researchers are actively searching for new treatments, and now, a group have found that acaí berry extracts can reduce parasites in the blood and prolong the survival of infected mice.

In Baltimore, lower income neighborhoods have bigger mosquitoes

Science Daily - October 16, 2019 - 13:49
Low-income urban neighborhoods not only have more mosquitoes, but they are larger-bodied, indicating that they could be more efficient at transmitting diseases. So reports investigating how socioeconomics influences mosquito-borne disease risk in Baltimore, Maryland.

Key uncertainties identified for models of mosquito distribution in the US

Science Daily - October 10, 2019 - 18:20
A computational analysis has identified key regions in the United States where model-based predictions of mosquito species distribution could be improved.

For the first time, professor observes crystallized iron product, hemozoin, made in mammals

Science Daily - October 1, 2019 - 15:08
For the first time ever, a professor has observed a crystallized iron product called hemozoin being made in mammals, with widespread implications for future research and treatment of blood disorders. Findings could be used to treat sickle cell disease and malaria patients, while opening up diverse research avenues across immunology, parasitology, neuroscience, microbiology, and even urology.

AMF activity update: September 2019

Against Malaria news - September 30, 2019 - 19:09

A short update on activities going on in-country this month.

  • In DRC, preparations are being made for the distribution of 1.5 million nets in Équateur province, which is due to begin mid-October. Nets have arrived in province and are being sent to the health zones in the correct quantities according to registration data. Nets are also arriving in Sud Ubangi province, where the registration of 600,000 households will begin in the coming weeks using electronic devices. Half the nets purchased were PBO nets, and half standard nets, and the effectiveness of these nets will be monitored. In Haut Katanga, registration of 1.4 million households will take place in October using paper forms. The printing of these forms is complete and we are engaging with our data entry partner, AGAPE, to put in place a data entry centre in Kinshasa. 8.4 million nets have been produced for the provinces of Tanganyika, Haut Katanga and Haut Lomami and are being shipped to the port of Dar Es Salam in Tanzania, and from there to Eastern DRC.
     
  • In Zambia, our partner CHAZ has just finished post-distribution monitoring in Western province, completing the first round of PDMs in all four provinces receiving AMF-funded nets. Across these provinces, the sleeping space coverage is 65%, with a hang up rate of 81%. This is low and we are investigating with our partners in country. One explanation is that AMF nets are generally being used, but too few were given out during distribution to cover all sleeping spaces. 3.0 million nets were distributed in 2018.
     
  • In Ghana, our partner World Vision has completed data collection for the 9-month PDM in Upper East region using electronic devices. Photos below. The results of the PDM in Brong Ahafo region have been imported into AMF's database and show a sleeping space coverage of 84% at 9 months post distribution.
     
  • In Malawi, our partner the Malawi Red Cross Society has collected PDM data in 6 districts in Southern region, which show an average sleeping space coverage of 73% at 9 months post distribution. Data is currently being collected in Central region.
     
  • In Guinea, we are currently investigating a possible theft of AMF nets and are working closely with all partners to 1) establish if the nets recovered in Mali are AMF-funded nets, and 2) conduct, as necessary, a thorough audit of the movement of all nets in country.
     
  • In Uganda, lists of specific households in specific villages, randomly selected by AMF, that will visited during PDM activity have been shared with our partner organisation Malaria Consortium for the 30-month PDM taking place in the Eastern region. Results from the 24-month PDM in selected districts in the Western region show a sleeping space coverage of 83%.
     
  • In PNG, our partner RAM continues to distribute nets on a rolling basis. So far in 2019, more than 395,000 nets have been successfully distributed in the provinces of Southern Highlands, Hela, Oro and Central. Distribution is ongoing in the New Ireland and North Solomons (ARoB) provinces. In total, about 1.0 million nets will be distributed during 2019. PDM activity has just been completed in Milne Bay, two years after the distribution, and data is being entered for review.
     
  • In Togo, preparations are taking place for the 24-month PDM which will take place in all four regions (Savanes, Kara, Centrale and Plateaux) that received 2.4 million nets in 2017. Data will be collected using electronic devices.

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