Reply to: The clinical implications of thrombocytopenia in adults with severe falciparum malaria: a retrospective analysis
It's great that you are getting thoughts from this piece of writing as well as from our discussion made at this time.
Reply to: Are Artemisia annua plantations killing fields?
A very recent paper from Iran (MH Bijeh Keshhavarzi et al, J Biol & Envir Sci. Nov 2014) describes the allelopathic effects of Artemisia annua on lettuce Lactuca sativa. The aqueous extract on an outside plot significantly reduced germination percentage and rate, fresh and dry weight.
Another paper (Seyed Mohsen et al., Annals of Biological Research, 2011, 2-6, 687-69) describes the allelopathic effect of Artemisia annua aqueous extracts on vegetables and plants like Portulaca olearcea (pursley), Chenopodium album (goose-foot), Avena ludoviciana (oat), Plantago ovata (plantain). For the latter the effects are noticeable on germination percentage, germination rate, plumule length, radicle length, wet weight, dry weight.
A Chinese paper (Shen He et al., Ying Yong Sheng Tai Xue Bao. 2005 Apr;16(4):740-3) had previously studied the allelopathy of different plants. Artemisia annua affected the seedling height and fresh weight of radish, cucumber, wheat and maize around 50%.
Reply to: World Malaria day: Vestergaard infographic about insecticide resistance
it is not a bit strange that in 3 studies WHopes made, there is no better control of P3 than of P2, but in two studies VF paid for in Nigeria, there is a better control. And here the lead scientist of these studies demand that strategies must be made to maximize its use (that means, it's sales). But i do recognize that the WHO organisation is sending out confusing messages. On one side, you have Whopes directed studies that clearly says that Permanet 3 - and especially Pemanet 3 washed - is not better than P2 on resistant Anopheles and Culex. On the other side you have a new committee of WHO that says that Vf provided evidence that Permanet 3 was in a new category. When you read what this group should use as evidence, it should be transmission impact to recognize a "new paradigme". But the group writes that there was NO evidence of transmission effect of P3 in areas with metabolic resistance, but still they conclude that here is a new paradigme. Maybe WHO has become so eager to show they are flexible, that they forget the rules they defined themselves ?
Reply to: Geophagia, Artemisia afra and Tuberculosis
Buruli, leprosy and tuberculosis are among the major killers in Africa. And endless suffering. Because chemical drugs sold by pharmaceutical companies from the North have failed or the resistance of mycobacterium to these drugs is becoming overwhelming.
It is very encouraging to find on internet the following project in Ghana
IN-VITRO SUSCEPTIBILITY OF MYCOBACTERIUM ULCERANS TO HERBAL PREPARATIONS
For several of the herbs involved in this project the inhibition of mycobacteria is equivalent or better than for Pefloxacin and/or Miconazole.
But the most encouraging are the conclusions of this WHO sponsored project :
A single herb is never a single compound but a group of compounds which potentiate each other or create synergy. The use of an herb or herbal cocktail would simulate combination therapy, which may prevent, or at least delay the development of microbial resistance.
Reply to: Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum
What is the aconite orocrycum