Over the past decades, Research and Development has played a key role in driving the achievements made against malaria with the development of tools such as rapid diagnostic tests (RDTs), artemisinin-combination therapies (ACTs) and long-lasting insecticide-treated nets (LLINs). We have also made great progress in our capacity to disseminate the scientific information to the malaria community; open access journals, webs, blogs, twitter, emails, conferences, publications, etc.
Although these problems do not have much significance in the Environmental Pathway to Malaria Suppression described in my previous blog, they are two major problems for folks following the WHO Chemical Dependency Pathway. They are:
Although I have presented these ideas previously, I found a new way of explaining the concepts which I hope you will find easier to understand, or to disagree with!
10 November 2014
THE SUCCESSFUL ENVIRONMENTAL PATHWAY TO PERMANENT MALARIA SUPPRESSION
Artemisia annua has strong allelopathic properties as was documented by Mediplant for the high artemisinin hybrid. In other words the plant becomes invasive and inhibits the growth of other plants or cash crop on fields where Artemisia has been planted for the extraction of artemisinin by Bigpharma.
With WHO's blessing Keasling's synthetic artemisinin replaces the natural product: an economical disaster for African families who have invested all their meager resources in Artemisia annua plantations, lured by the promise of big profits.
MESA is very excited to be launching its new website and knowledge management tools at ASTMH in New Orleans on November 2nd!
Major differences in the two principal attacks on malaria during the Twentieth Century
It is fortunate that the international agencies responsible for attacking malaria are all in a state of self-examination this year, seeking better and more durable strategies. To this end, I have recently submitted suggestions to the World Health Organization, to the US Presidential Malaria Initiative and to the UN Roll Back Malaria Program, outlining how they could avoid repeating the collapse of the first Global Malaria Eradication Program, by broadening their current strategies.
Constant Tchandema and Pierre Lutgen
Potassium, the most abundant cation in the human body, regulates intracellular enzyme function and neuromuscular tissue excitability. Serum potassium is normally maintained within thenarrow range of 3.5 to 5.5 mEq/L.
The Second Global Malaria Action Plan (GMAP2) will cover the timeframe 2016-2025.
You are strongly encouraged to have a look and contribute by sharing your vision for a malaria-free world.
A very important paper posted on www.malariaworld.org (Enabling factors facilitating the use of neem-based remedies for the management of malaria … ).
An apotheosis of herbal medicine
It documents in an excellent way the superiority of herbal medicine against malaria when compared with ACTs.
Clinical trials are not suitable to identify rare, potentially serious adverse effects of drugs, or to define their safety in high risk populations.
Artemisinin-based combination therapies (or ACTs) are considered safe, but there are concerns over their potential to cause damage to parts of the brain. There is also a concern about their safety in patients infected with HIV.
The column below was contributed by by Rasha Azrag & Guy Reeves.
"I am always wary of ‘technology-led’ solutions. The under-developed world is littered with rusting tractors and broken water pumps." 
Surprisingly, this quote is from a document that promotes a technology; which is pictured below. While it might at first glance look like a dried-up reservoir it is in fact a fully functioning sand dam that provides year-round clean water in a water scarce environment.
The column below was contributed by Jenni Lawton.
With the Scottish Independence Referendum looming on the 18th September 2014, here we are all waiting with bated breath to see what the outcome will be. I thought this would be a good time to reflect on Scotland’s contribution to the understanding and treatment of tropical diseases, including malaria.
This is an urgent plea to you - the reader - to support strengthening of the strategy being used by the US Presidential Malaria Initiative of USAID in Africa. Please contact Tim Ziemer or his deputy Bernard Nahlen at USAID in Washington DC to support strengthening of their malaria strategy by broadening it to include all available control methods in the most cost-effective combination.
We propose that WHO should adopt a holistic Generalist Approach in their new malaria strategy.
W.Jobin of Blue Nile Associates and F.Snowden of Yale University
and including deliberations with many malariologists resulting in the Yale University Declaration on Malaria in 2006, and the Jerusalem Declaration on Malaria in 2013, both of which are available on this website.
8 August 2014
Cambodia is moving towards eliminating malaria. According to the WHO World Malaria Report, less than 100 deaths were attributable to malaria in 2012 (World Malaria Report 2013).
In the 1970s, there were only about nine countries where dengue fever existed but now the number is closer to 60. As of 2010 dengue fever is believed to infect 50 to 100 million people worldwide per year with 1/2 million life-threatening infections There is no cure and no real treatment.
We are all pleased with development and posting of the Jerusalem Declaration on Malaria of December 2013. It follows in the footsteps of a previous Declaration on Malaria issued at Yale University in November of 2008. Please compare the two, they show remarkable similarities.
Both Declarations came after several days of discussions by people with a passionate interest in suppressing malaria in Africa, motivated by the reminder that a million people die of malaria in Africa every year, and most of them are children.