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Background reading Keystone Symposium The Science of Malaria Eradication, February 2-7, 2014 Mexico

January 22, 2014 - 17:06 -- MESA Alliance

Find the background reading for the Keystone Symposium here, for those long hours in the plane!

B. Fenton Hall and Anthony S. Fauci (2009)
The Journal of Infectious Diseases 2009;200:1639–43
 
malERA group: Alonso PL, Brown G, Arevalo-Herrera M, Binka F, Chitnis C, et al. (2011)
PLoS Med 8(1): e1000406
 
Sibao Wang and Marcelo Jacobs-Lorena (2013)
Trends in Biotechnology, March 2013, Vol. 31, No. 3
 
Ashley J. Birkett, Vasee S. Moorthy, Christian Loucq, Chetan E. Chitnis and David C. Kaslow (2013)
Vaccine, Volume 31, Supplement 2, 18 April 2013, Pages B233–B243

New WHO Collaborating Centre in Geospatial Disease Modelling

January 20, 2014 - 14:35 -- Bart G.J. Knols
The University of Oxford has received designation as a World Health Organization (WHO) Collaborating Centre in Geospatial Disease Modelling. Based in the Spatial Ecology and Epidemiology Group (SEEG) in the Department of Zoology, this new designation primarily recognises the contributions of SEEG to supporting the modelling, monitoring and evaluation activities of the WHO Global Malaria Programme.

Palestinians discover local plant with surprisingly strong antimalarial properties.

January 20, 2014 - 13:25 -- Pierre Lutgen

The research team from the Al Quds University has already shown that some plants from Palestine have a strong inhibitory effect on beta-hematin crystallisation. Salvia officinalis (M Akkawi et al., Malaria Journal, 2012, 11-Suppl,P3) and Artemisiasieberi from Palestine ( M Akkawi et al. Brit J Pharmacol Toxicol, accepted 2013). The therapeutic effect of quinine, chloroquine, amodiaquine is precisely based on hemozoin inhibition.

What should we do: Peer review or not?

January 16, 2014 - 13:36 -- Bart G.J. Knols

The science world is undergoing rapid changes, and so does the field of scientific publishing. The Lancet recently featured five articles on the current value and reduction of waste in biomedical research. An article in the Economist from a few months before titled 'How science goes wrong' is another eye-opener. Clearly, much is changing in the science world, and this includes us scientists working on malaria.

Here we are asking for your views regarding an issue we are discussing for the MalariaWorld Journal, entering its 5th volume this year: Should we continue with peer review, yes or no, or should we perhaps make it optional?

The digestive vacuole and malaria resistance ; the weakness of artesunate.

January 9, 2014 - 11:04 -- Pierre Lutgen

The diffusion of antimalarials into infected red blood cells has been studied by several authors. For example, three times more chloroquine accumulates in CQ sensitive strains than in the CQ resistant ones (KJ Saliba et al., Biochem Pharmacol. 1998, Aug 1 ;56, 313-20) Thediffusion of artemisinin into parasitized RBCs was found to be rapid, saturable, temperature dependent, irreversible. In contrast, simple passive diffusion of artemisinin was seen in nonparasitized RBCs.(N Vyas, Antimicro Ag Chemother, Jan 2002, 105-109).

Debate: adults or larvae?

January 7, 2014 - 13:15 -- William Jobin

Why are there two completely opposing views about the value of direct attacks on anopheline mosquito larvae or on adults, for suppressing malaria transmission ?

In recent public and written debates, I have seen diametrically and vehemently opposed views expressed on the value of attacking larvae through eliminating breeding sites, as opposed to the current emphasis on reducing biting by anopheline adults through bednets and indoor spraying.

Audio: Outstanding ASTMH presentations relevant to malaria elimination: 2

December 16, 2013 - 21:55 -- MESA Alliance
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Did you miss unmissable presentations at this year's ASTMH?
Listen here:
 
 
'Establishing Malaria-Free Zones in Zanzibar and Zambia: Progress and Next Steps'.
 
Chairs: Richard Steketee (PATH MACEPA) and Anders Björkman (Karolinska Institute).
 
 
 
 
 
 
MESA will post other great sessions on malaria elimination for you to listen to and download, watch this MalariaWorld page.

Audio: Outstanding ASTMH presentations relevant to malaria elimination: 1

December 16, 2013 - 16:50 -- MESA Alliance
Tags: 
Did you miss unmissable presentations at this year's ASTMH?
Listen here:
 
 
Fred L. Soper Lecture held at the 2013 ASTMH annual meeting.
'History of the regional initiative to eliminate river blindness from the Americas'. Speaker Frank O. Richards, The Carter Center.

"If you find Soper interesting, I really enjoyed the book by Prof Stepan, if you get a chance have a look" (Frank O. Richards). 

 PLAY 

 

Frank O. Richards has provided his slide deck, see attched file (5,7 MB).

MESA will post other great sessions on malaria elimination for you to listen to and download, watch this MalariaWorld page.

How much time needed to vaccinate the world against malaria?

December 9, 2013 - 04:08 -- Andy Graham

The polio vaccination was discovered in 1952, announced to world in 1955. A global effort to eradicate polio, led by the World Health Organization, UNICEF, and The Rotary Foundation, began in 1988. Using today, December 9, 2013 as a starting point, how long would it take to eradicate malaria worldwide?

Press release: Malaria Conference Will Look to Israel’s Past for Modern Solutions

December 8, 2013 - 15:23 -- Bart G.J. Knols
MEDIA ADVISORY
INTERVIEWS AVAILABLE
 
Malaria Conference Will Look to Israel’s Past for Modern Solutions
Techniques that worked decades ago could help stop the annual 660,000 malaria deaths
Experts, field workers and historians will gather Dec. 8-12 in Jerusalem
Forgotten anti-malaria pioneer and his innovations to be recognized

Does Acoustic Larvicide Work? What are pros and cons?

December 7, 2013 - 15:13 -- Andy Graham

Acoustic Larvicide is a technique where mosquito larvae are killed by rupturing their internal air bladders with acoustic energy. Their air bladders are resonant and therefore susceptible to acoustic energy in the octave from 18 kilohertz to 30 kilohertz. When sound at these frequencies with sufficient energy is put in the water the mosquito larvae instantly die.

This company, New Mountain Innovations appears to be the leader of this idea. Larvasonic.com

http://www.larvasonic.com/history2.html

Hebrew University - Malaria conference (8-12 December)

December 5, 2013 - 10:57 -- Bart G.J. Knols

From 8-12 December, a conference titled 'Revisiting Malaria: Moving from Control to Sustainable Elimination' will be organised at the Hebrew University-Hadassah, Jerusalem, Israel.

The meeting conincides with the Centennial commemoration of the activities undertaken by Prof. Israel Kligler (picture, 2nd row, left), who was instrumental in eliminating malaria from Palestine. Malaria that in many ways was similar in intensity and impact as malaria seen in many parts of Africa today.

The meeting will be held in the form of a workshop and lectures, looking at past historical successes in malaria elimination, reviewing our current focus, and looking forward to identify what will be needed to move from control to sustainable elimination.

Also, workshop participants will work on scenario's for malaria elimination in island settings and ecological islands. The aim is to assist managers of NMCPs in moving forward in their country towards malaria elimination.

Participants have been selected from a variety of backgrounds that are considered essential in the planning and execution of operational malaria programmes.

Outputs from the meeting will be reported here on MalariaWorld, including a declaration by the participants.

The meeting is generously supported by the following organisations:

Kuvin Foundation, Braun School of Public Health & Community Medicine; Hebrew University, Faculty of Medicine-Hadassah; Hadassah; British Friends of Hebrew University; Pears Foundation (UK); Jewish National Fund/Keren Keyemeth LeIsrael; TEVA; and The Kuvin Center for the Study of Infectious and Tropical Diseases.
 

Was artemisinin the wrong choice; is arteannuin-B the better one?

December 2, 2013 - 20:55 -- Pierre Lutgen

A recent paper (Anti-Plasmodial Polyvalent Interactions in Artemisia annua L. Aqueous Extract - Possible Synergistic and Resistance Mechanisms J J Suberu et al., PLoS ONE, November 2013 8 |11) opens the way for new antimalarial therapies. It provides answers to several questions which had not been addressed properly in the scientific literature. The paper studied the additive, synergistic or antagonistic effect of several constituants of Artemisia annua. It confirms clearly that the aqueous extract of Artemisia annua is three times as potent as pure artemisinin.

WHO/PAHO honours malaria champions in the Americas

November 21, 2013 - 19:20 -- MESA Alliance
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On 6 November 2013, WHO/ PAHO honoured initiatives from three malaria-endemic countries with the ‘Malaria Champions of the Americas Awards’. The Malaria Champions of the Americas awards were given to Colombia (Colombia Malaria Project), the Dominican Republic (National Center for Control of Tropical Diseases), and Brazil (Secretariat of Health of the State of Acre). The Malaria Champions of the Americas was launched in 2008 to identify, celebrate and inspire excellence in efforts to fight the disease.

Fact or Fallacy? Vector control is a major part of malaria interventions.

November 18, 2013 - 09:15 -- Mark Benedict

It is often asserted that there are two malaria vector interventions in widespread use: long-lasting insecticide treated bednets (LLIN) and indoor residual insecticide spraying (IRS). Are either of these vector interventions? I’ll argue that the answer is, “No!” What does this mean for the development of new methods?

PAMCA: Win a student membership (deadline 16 December)

November 14, 2013 - 08:24 -- Bart G.J. Knols
Following a generous donation by Dr. Brian D. Anderson, the Pan-African Mosquito Control Association is pleased to announce an essay competition for award of 10 student memberships. The competition is open to African nationals studying an undergraduate or postgraduate programme at any higher learning institute.
 
Essays should be: a) written for a general rather than highly technical audience, b) on a topical issue concerning mosquitoes (which may include mosquito control or mosquito-borne diseases), c) maximum 500 words in either English, French or Portuguese. Essays will be judged based on topic, content and readability. The focus should be on creating an interesting and engaging short piece.
 
Student essays should be submitted to info@pamca.org by 16th December 2013. Undergraduate and post-graduate entries will be judged separately. Winners will receive one year of membership to PAMCA. Winning essays will be featured on www.pamca.org and MalariaWorld along with the student biography. Further details are included in the attachment. Queries should be directed to info@pamca.org
 
Remember to mention MalariaWorld when you submit your essay.
 
Best regards,
 
Dr Tessa B. Knox
PAMCA Communications

Resurging Malaria Catches Cameroon Napping

November 12, 2013 - 08:34 -- Bart G.J. Knols
The article below was contributed by journalist Ntaryike Divine Jr. (Douala, Cameroon). 
 
In 2008, the government of Cameroon engaged a policy-swing designed to irreversibly roll back malaria.  The strategy entailed providing free treatment for simple malaria for under-fives and pregnant women, a countrywide gratis distribution of treated bednets, as well as increased consciousness campaigns.
 
Initially, the Ministry of Health appeared to be winning the war against the bloodthirsty mosquitoes that have hemmed Cameroon among malaria endemic territories over the years.  In fact, earlier this year, officials were upbeat about sustaining the victory.    
 
“If we make a comparison between the current situation and what we saw in 2008, we note that malaria-related morbidity has dropped.  Related mortality among under-fives has decreased from 144 to 122 per hundredthousand thanks to actions taken by the Ministry and we’re lobbying for another campaign to distribute free bednets in 2014,” boasted Dr Etienne Fondjo, permanent secretary of the Program to Fight against Malaria.

Keystone Symposia Meeting on The Science of Malaria Eradication

November 10, 2013 - 16:24 -- MESA Alliance
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Date: Sunday, 2 February 2014 - Friday, 7 February 2014
Location: Mérida (Yucatán) México
Scientific Organizers: Pedro L. Alonso, Chetan E. Chitnis and Lee Hall
Organized in collaboration with MESA – Malaria Eradication Scientific Alliance

MalariaWorld is looking for columnists (deadline 15 December)

November 7, 2013 - 21:58 -- Bart G.J. Knols

MalariaWorld is looking for authors to write columns about malaria - in the broadest sense. What we all read in scientific articles on malaria is only the tip of the iceberg when it gets to the world of malaria. Our malaria world is shaped by funding agencies, meeting outcomes, opinionated individuals and politics, but also you.

How to improve manuscript reviewing?

November 5, 2013 - 20:23 -- Bart G.J. Knols

MalariaWorld as of today has 8102 registered members. We continuously check the validity of your email address to make sure that we remain connected with you, so you and 8101 other subscribers receive the MalariaWorld newsletter every single week of the year. This November we celebrated our fourth year of providing services to you. This was also a time to once more review our progress, including the progress we are making with the MalariaWorld Journal. The journal is now in its 4th volume and it is maturing, but we identified some real difficulties, one of which I want to bring to your attention here: manuscript reviewing...

MESA opens call for proposals

November 4, 2013 - 22:06 -- MESA Alliance
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The MESA grants will support operational research on preventing the spread, or reintroduction, of malaria transmission between neighboring areas, or from hotspots/pockets of transmission. 
 
Proposals must address innovative approaches to reach zero malaria transmission, or to prevent the reintroduction of malaria, in a specific zone which has neighboring areas where transmission still occurs; e.g. within district, at subnational level, between island and mainland, or at cross-border areas.

Malaria Day in the Americas- November 6

October 21, 2013 - 19:32 -- Prabhjot Singh

In commemoration of Malaria Day in the Americas 2013

 

The Pan American Health Organization,

The Pan American Health and Education Foundation, and

The Center for Global Health at The George Washington University

 

Cordially invite you to attend the

Malaria in the Americas Forum 2013:

Haemolytic, hepatotoxic, cytotoxic, neurotoxic, cardiotoxic, genotoxic, ototoxic, embryotoxic, spleenotoxic, hemolytic, atherosclerosis, immunodepressive effects of chemical artemisinine derivatives (ACTs) at high doses.

October 19, 2013 - 19:48 -- Irene Teis

Haemolytic, hepatotoxic, cytotoxic, neurotoxic, cardiotoxic, genotoxic, ototoxic, embryotoxic, spleenotoxic, hemolytic, atherosclerosis, immunodepressive effects of chemical artemisinine derivatives (ACTs) at high doses.

Some recent research, mostly in relation with the resistance to ACT pills and/or artesunate injections, has highlighted serious secundary health effects at the doses prescribed by WHO.

Keystone symposium: The science of eradication

October 14, 2013 - 15:45 -- MESA Alliance

Date: February 2-7, 2014

Location: Mérida, Yucatán, México

Scientific Organizers: Pedro L. Alonso, Chetan E. Chitnis and Lee Hall
Organized in collaboration with MESA – Malaria Eradication Scientific Alliance

Part of the Keystone Symposia Global Health Series, travel awards supported by the Bill & Melinda Gates Foundation. Click for the Program and more information .
 

BVGH Recruits Dr. Linda Venczel as New Program Director

October 11, 2013 - 13:34 -- Ingeborg van Schayk

Dr. Linda Veronica Venczel of Seattle has been appointed BIO Ventures for Global Healths new Director of Program and Partnership Management.  Most recently Dr. Venczel was Senior Program Officer, Global Development at the Bill & Melinda Gates Foundation, Deputy Branch Chief for Polio Eradication at the Centers for Disease Control and Prevention in Atlanta, and International Advisor on Vaccines and Immunization for Bolivia at the Pan American Health Organization in Washington DC.

Malaria Eradication Scientific Alliance

October 11, 2013 - 09:38 -- MESA Alliance
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MESA (the Malaria Eradication Scientific Alliance) follows-up on the malERA agenda and provides a dedicated platform for the community in order to accelerate the translation of the science of malaria eradication for impact.
 

With the community, MESA monitors progress and takes the next steps to advance the science of malaria eradication. MESA reviews existing evidence and supports projects on research questions critical to malaria eradication. For more information, please visit www.mesamalaria.org.

Read MESA's latest posts here.

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